JP7496917B2 - Kras g12c阻害剤の投与レジメン - Google Patents
Kras g12c阻害剤の投与レジメン Download PDFInfo
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- JP7496917B2 JP7496917B2 JP2023108177A JP2023108177A JP7496917B2 JP 7496917 B2 JP7496917 B2 JP 7496917B2 JP 2023108177 A JP2023108177 A JP 2023108177A JP 2023108177 A JP2023108177 A JP 2023108177A JP 7496917 B2 JP7496917 B2 JP 7496917B2
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| EP4687905A1 (en) | 2023-03-30 | 2026-02-11 | Revolution Medicines, Inc. | Compositions for inducing ras gtp hydrolysis and uses thereof |
| AU2024265078A1 (en) | 2023-05-04 | 2025-12-11 | Revolution Medicines, Inc. | Combination therapy for a ras related disease or disorder |
| IL326136A (en) | 2023-08-07 | 2026-03-01 | Revolution Medicines Inc | RMC-6291 for use in the treatment of a disease or disorder associated with the RAS protein |
| US20250154171A1 (en) | 2023-10-12 | 2025-05-15 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| US20250375445A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
Citations (3)
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| WO2021222333A1 (en) | 2020-04-30 | 2021-11-04 | Genentech, Inc. | Kras specific antibodies and uses thereof |
| JP2022508469A (ja) | 2019-12-11 | 2022-01-19 | イーライ リリー アンド カンパニー | Kras g12c阻害剤 |
| WO2022060836A1 (en) | 2020-09-15 | 2022-03-24 | Revolution Medicines, Inc. | Indole derivatives as ras inhibitors in the treatment of cancer |
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| MY141867A (en) | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
| US7141568B2 (en) | 2003-07-09 | 2006-11-28 | Pfizer Italia S.R.L. | Pyrrolo[3,4-c]pyrazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them |
| CL2007003244A1 (es) | 2006-11-16 | 2008-04-04 | Millennium Pharm Inc | Compuestos derivados de pirimido[5,4-d][2]benzazepina; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento del cancer. |
| US20230285498A1 (en) * | 2020-08-07 | 2023-09-14 | City Of Hope | Treatments for cancers having kras mutations |
| EP4486345A1 (en) * | 2022-03-04 | 2025-01-08 | Eli Lilly and Company | Method of treatment including kras g12c inhibitors and shp2 inhibitors |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2022508469A (ja) | 2019-12-11 | 2022-01-19 | イーライ リリー アンド カンパニー | Kras g12c阻害剤 |
| WO2021222333A1 (en) | 2020-04-30 | 2021-11-04 | Genentech, Inc. | Kras specific antibodies and uses thereof |
| WO2022060836A1 (en) | 2020-09-15 | 2022-03-24 | Revolution Medicines, Inc. | Indole derivatives as ras inhibitors in the treatment of cancer |
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| MA71325A (fr) | 2025-04-30 |
| CN119907671A (zh) | 2025-04-29 |
| US20240108618A1 (en) | 2024-04-04 |
| CA3260047A1 (en) | 2024-01-04 |
| AU2023297941A1 (en) | 2025-01-16 |
| MX2025000105A (es) | 2025-02-10 |
| JP2024007504A (ja) | 2024-01-18 |
| KR20250027777A (ko) | 2025-02-27 |
| WO2024006424A1 (en) | 2024-01-04 |
| JP2024112968A (ja) | 2024-08-21 |
| IL317823A (en) | 2025-02-01 |
| TW202421145A (zh) | 2024-06-01 |
| EP4547251A1 (en) | 2025-05-07 |
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