JP7485331B2 - リアルタイム画像誘導放射線療法のための方法 - Google Patents

リアルタイム画像誘導放射線療法のための方法 Download PDF

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JP7485331B2
JP7485331B2 JP2019565835A JP2019565835A JP7485331B2 JP 7485331 B2 JP7485331 B2 JP 7485331B2 JP 2019565835 A JP2019565835 A JP 2019565835A JP 2019565835 A JP2019565835 A JP 2019565835A JP 7485331 B2 JP7485331 B2 JP 7485331B2
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radiation
fluence
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image
matrix
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イェフゲン ボロネンコ,
ピーター ディミトリ オルコット,
デバシシュ パル,
ロステム バッサロー,
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リフレクション メディカル, インコーポレイテッド
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    • AHUMAN NECESSITIES
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    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1064Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • A61N5/1065Beam adjustment
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    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1061Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source
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    • A61N5/1068Gating the beam as a function of a physiological signal

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Optics & Photonics (AREA)
  • Pulmonology (AREA)
  • Theoretical Computer Science (AREA)
  • Radiation-Therapy Devices (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
JP2019565835A 2017-05-30 2018-05-30 リアルタイム画像誘導放射線療法のための方法 Active JP7485331B2 (ja)

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JP2023008740A JP2023041769A (ja) 2017-05-30 2023-01-24 リアルタイム画像誘導放射線療法のための方法
JP2025003926A JP2025061196A (ja) 2017-05-30 2025-01-10 リアルタイム画像誘導放射線療法のための方法

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US201762512632P 2017-05-30 2017-05-30
US62/512,632 2017-05-30
US201762537384P 2017-07-26 2017-07-26
US62/537,384 2017-07-26
PCT/US2018/035188 WO2018222751A1 (en) 2017-05-30 2018-05-30 Methods for real-time image guided radiation therapy

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Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103650095B (zh) 2011-03-31 2016-12-07 反射医疗公司 用于在发射引导的放射治疗中使用的系统和方法
US10632326B2 (en) * 2015-12-18 2020-04-28 Washington University System and method for radiation treatment optimized for non-coplanar delivery
WO2017156316A1 (en) 2016-03-09 2017-09-14 Reflexion Medical, Inc. Fluence map generation methods for radiotherapy
WO2018093849A1 (en) 2016-11-15 2018-05-24 Reflexion Medical, Inc. Methods for radiation delivery in emission-guided radiotherapy
US10702715B2 (en) 2016-11-15 2020-07-07 Reflexion Medical, Inc. Radiation therapy patient platform
CN110997063B (zh) 2017-05-30 2022-04-29 反射医疗公司 用于计算放射注量的方法的放射治疗系统
US11648418B2 (en) 2017-06-22 2023-05-16 Reflexion Medical, Inc. Systems and methods for biological adaptive radiotherapy
US10456600B2 (en) 2017-07-26 2019-10-29 Reflexion Medical, Inc. Graphical representation of radiation therapy
US10617888B2 (en) 2017-09-22 2020-04-14 Reflexion Medical, Inc. Systems and methods for shuttle mode radiation delivery
CN119701229A (zh) 2018-02-13 2025-03-28 反射医疗公司 光束站治疗计划和放射输送方法
GB2572366B (en) * 2018-03-27 2021-08-18 Elekta ltd Imager
US11027152B1 (en) 2018-08-06 2021-06-08 Integrated Sensors, Llc Ionizing-radiation beam monitoring system
US10525285B1 (en) * 2018-08-06 2020-01-07 Integrated Sensors, Llc Ionizing-radiation beam monitoring system
US10828513B2 (en) 2018-08-06 2020-11-10 Integrated Sensors, Llc Ionizing-radiation beam monitoring system
WO2020112673A1 (en) * 2018-11-30 2020-06-04 Accuray Inc. Method and apparatus for improving scatter estimation and correction in imaging
US11357467B2 (en) 2018-11-30 2022-06-14 Accuray, Inc. Multi-pass computed tomography scans for improved workflow and performance
US20220023666A1 (en) * 2018-12-10 2022-01-27 University Health Network Artificial neural network based radiotherapy safety system
US12109438B2 (en) * 2018-12-26 2024-10-08 Our United Corporation Positioning method realized by computer, and radiotherapy system
KR102648198B1 (ko) * 2019-01-14 2024-03-19 삼성디스플레이 주식회사 잔상 보상부 및 이를 포함하는 표시 장치
WO2020150505A1 (en) 2019-01-16 2020-07-23 Reflexion Medical, Inc. Methods for setup corrections in radiation therapy
US11052265B2 (en) * 2019-02-11 2021-07-06 Troy Long Fluence map optimization for field-in-field radiation therapy
US11633623B2 (en) * 2019-04-19 2023-04-25 University Of Maryland, Baltimore System and method for radiation therapy using spatial-functional mapping and dose sensitivity of branching structures and functional sub-volumes
CN114401674B (zh) * 2019-07-12 2025-03-11 反射医疗公司 放射治疗的多靶治疗计划和递送以及虚拟定位
WO2021108684A1 (en) * 2019-11-25 2021-06-03 The Regents Of The University Of California Systems and methods for dynamic control of radiation dose in radiation therapy
EP3834886B1 (en) 2019-12-11 2025-06-18 RaySearch Laboratories AB Providing a treatment plan for radiotherapy when the delivery is interrupted
GB2590454B (en) * 2019-12-18 2022-01-05 Elekta ltd A method of characterising physical properties of an attenuating element in a radiotherapy device
CN110975172B (zh) * 2019-12-18 2022-05-31 上海联影医疗科技股份有限公司 一种通量图重建方法和系统
US12274895B2 (en) 2019-12-20 2025-04-15 Elekta Ab (Publ) Adaptive dose accumulation algorithm
WO2021154746A1 (en) * 2020-01-28 2021-08-05 Reflexion Medical, Inc. Joint optimization of radionuclide and external beam radiotherapy
US11166690B2 (en) 2020-03-19 2021-11-09 Accuray, Inc. Noise and artifact reduction for image scatter correction
EP3892327B1 (en) * 2020-04-06 2024-05-08 RaySearch Laboratories AB Radiation therapy treatment planning
GB2598273B (en) * 2020-05-01 2023-03-29 Elekta ltd Patient positioning for radiotherapy treatment
CN115697481B (zh) * 2020-06-29 2025-05-13 上海联影医疗科技股份有限公司 放射治疗计划系统和方法
EP4178670A4 (en) * 2020-07-10 2024-12-25 University of Sydney DOSE-BASED OPTIMIZATION FOR MULTI-LEAF COLLIMATOR (“MLC”) TRACKING DURING RADIOTHERAPY, METHODS AND APPARATUS
CN112154483B (zh) * 2020-07-15 2025-04-04 北京肿瘤医院(北京大学肿瘤医院) 一种利用光学体表运动信号合成实时图像的方法及系统
WO2022031750A1 (en) * 2020-08-07 2022-02-10 Reflexion Medical, Inc. Multi-sensor guided radiation therapy
US11478661B2 (en) 2020-09-29 2022-10-25 Varian Medical Systems International Ag Trajectory optimization using dose estimation and conflict detection
WO2022098794A1 (en) * 2020-11-04 2022-05-12 Reflexion Medical, Inc. Methods for tumor tracking
JP2024510079A (ja) * 2021-01-26 2024-03-06 アルドス エーピーエス 放射線療法システムの線量ガイダンス及び最終照射放射線量の反復推定のためのシステム及び方法
CN112581475B (zh) * 2021-02-25 2021-05-25 四川大学华西医院 一种预测放疗计划的伽马通过率的方法
EP4298594A2 (en) * 2021-02-26 2024-01-03 RefleXion Medical Inc. Methods for automatic target identification, tracking, and safety evaluation for radiotherapy
WO2022229916A1 (en) 2021-04-29 2022-11-03 Universidade Do Minho Method and device for generating an uncertainty map for guided percutaneous procedures
WO2022229937A1 (en) 2021-04-30 2022-11-03 Universidade Do Minho Method and device for registration and tracking during a percutaneous procedure
GB2607576B (en) * 2021-06-01 2023-12-06 Elekta ltd Driving gated treatment deliveries
CN113521558B (zh) * 2021-06-02 2022-10-28 上海联影医疗科技股份有限公司 容积调强计划生成系统
US11647975B2 (en) 2021-06-04 2023-05-16 Accuray, Inc. Radiotherapy apparatus and methods for treatment and imaging using hybrid MeV-keV, multi-energy data acquisition for enhanced imaging
FR3123994B1 (fr) * 2021-06-15 2023-06-02 Commissariat Energie Atomique Procédé de mesure optique de dosimétrie et dispositif de mesure optique de dosimétrie
US11638838B2 (en) 2021-06-30 2023-05-02 Accuray Incorporated 3D imaging with simultaneous treatment and non-treatment imaging beams
US11605186B2 (en) 2021-06-30 2023-03-14 Accuray, Inc. Anchored kernel scatter estimate
US11794039B2 (en) 2021-07-13 2023-10-24 Accuray, Inc. Multimodal radiation apparatus and methods
US11854123B2 (en) 2021-07-23 2023-12-26 Accuray, Inc. Sparse background measurement and correction for improving imaging
WO2023009332A1 (en) 2021-07-30 2023-02-02 Reflexion Medical, Inc. Dose coverage margin metric for evaluating radiotherapy treatment plans
JP2024539154A (ja) 2021-10-21 2024-10-28 リフレクション メディカル, インコーポレイテッド 生物学的誘導放射線療法のためのpet撮像解析のためのシステム及び方法
US12350523B2 (en) * 2021-10-22 2025-07-08 Viewray Systems, Inc. MRI guided radiotherapy
CA3244427A1 (en) * 2021-12-27 2023-07-06 Reflexion Medical, Inc. METHODS APPLICABLE TO QUALITY ASSURANCE IN RADIATION ADMINISTRATION
US11904186B2 (en) * 2022-01-12 2024-02-20 Capital Medical University Radiotherapeutical or radiosurgical system comprising two or more rotatable high-intensity radiation sources and a ring-shaped imager, and methods thereof
US12257083B2 (en) 2022-02-07 2025-03-25 Accuray Inc. Methods for saturation correction and dynamic gain configuration and apparatuses for performing the same
US11712584B1 (en) * 2022-05-24 2023-08-01 Accuray Incorporated Prospective and retrospective on-line adaptive radiotherapy
US11679281B1 (en) * 2022-06-01 2023-06-20 Accuray Incorporated Scalable slim radiotherapy treatment delivery system topology
US12303715B2 (en) * 2022-06-30 2025-05-20 Varian Medical Systems, Inc. Methods and apparatus for automatically determining radioablation treatment risk
JP2025526460A (ja) 2022-07-28 2025-08-13 レイシオ・セラピューティクス,インコーポレーテッド 線維芽細胞活性化タンパク質標的組成物およびその使用の方法
US20240100363A1 (en) * 2022-09-28 2024-03-28 Igor Sinitsyn Devices and methods for adaptively controlling a radiotherapy apparatus
EP4344735A1 (en) * 2022-09-28 2024-04-03 Elekta, Inc. Devices and methods for adaptively controlling a radiotherapy apparatus
CN120529942A (zh) 2022-11-15 2025-08-22 反射医疗公司 用于放射疗法的自适应相关滤波器
CN115829972B (zh) * 2022-12-02 2024-04-19 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 一种放疗计划三维剂量分布与通量的同步预测方法及装置
US12383765B2 (en) * 2023-06-08 2025-08-12 Siemens Healthineers International Ag Biological equivalent dose informed flash radiation therapy
EP4403211B1 (en) * 2023-06-30 2025-06-11 Siemens Healthineers AG A method for providing adapted 4d ct data
WO2025029608A1 (en) 2023-07-28 2025-02-06 Ratio Therapeutics, Inc. Fibroblast activation protein-targeted compositions and methods of use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060159220A1 (en) 2003-07-15 2006-07-20 Heuscher Dominic J Computed tomograhpy with large gantry bore
JP2012506734A (ja) 2008-10-27 2012-03-22 トモセラピー・インコーポレーテッド 放射線療法デリバリ用の運動適応最適化システムおよび方法
US20130188856A1 (en) 2011-12-01 2013-07-25 Varian Medical Systems, Inc. Systems and methods for real-time target validation for image-guided radiation therapy
WO2016023786A1 (en) 2014-08-15 2016-02-18 Koninklijke Philips N.V. Supervised 4-d dose map deformation for adaptive radiotherapy planning

Family Cites Families (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3794840A (en) 1972-03-27 1974-02-26 Charlotte Memorial Hospital Method and apparatus for directing a radiation beam toward a tumor or the like
AU568793B2 (en) 1985-07-26 1988-01-07 National Starch & Chemical Corporation Rmoistenable hot-melt adhesive of poly(alkyloxazoline)
US5647663A (en) 1996-01-05 1997-07-15 Wisconsin Alumni Research Foundation Radiation treatment planning method and apparatus
AU5194698A (en) 1996-10-24 1998-05-15 Nomos Corporation Planning method and apparatus for radiation dosimetry
US6023494A (en) 1996-12-19 2000-02-08 General Electric Company Methods and apparatus for modifying slice thickness during a helical scan
US6393096B1 (en) 1998-05-27 2002-05-21 Nomos Corporation Planning method and apparatus for radiation dosimetry
AU757570B2 (en) 1998-08-06 2003-02-27 Wisconsin Alumni Research Foundation Method for preparing a radiation therapy plan
US6438202B1 (en) 1998-08-06 2002-08-20 Wisconsin Alumni Research Foundation Method using post-patient radiation monitor to verify entrance radiation and dose in a radiation therapy machine
US6402689B1 (en) 1998-09-30 2002-06-11 Sicel Technologies, Inc. Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors
DE60018394T2 (de) 1999-04-02 2005-12-29 Wisconsin Alumni Research Foundation, Madison Megavolt-computertomographie während der strahlentherapie
WO2001076021A2 (en) 2000-03-31 2001-10-11 University Of Maryland, Baltimore Helical electron beam generating device and method of use
AU2001294604A1 (en) 2000-09-22 2002-04-02 Numerix Llc Improved radiation therapy treatment method
US6504899B2 (en) 2000-09-25 2003-01-07 The Board Of Trustees Of The Leland Stanford Junior University Method for selecting beam orientations in intensity modulated radiation therapy
US20040122308A1 (en) 2000-10-20 2004-06-24 Wei Ding Radiation dosimetry reports and a method of producing same
US6661870B2 (en) 2001-03-09 2003-12-09 Tomotherapy Incorporated Fluence adjustment for improving delivery to voxels without reoptimization
US6459762B1 (en) 2001-03-13 2002-10-01 Ro Inventions I, Llc Method for producing a range of therapeutic radiation energy levels
US6810108B2 (en) 2001-11-02 2004-10-26 Siemens Medical Solutions Usa, Inc. System and method for positioning an electronic portal imaging device
CA2478296A1 (en) 2002-03-06 2003-09-18 Tomotherapy Incorporated Method for modification of radiotherapy treatment delivery
SE522162C2 (sv) 2002-05-06 2004-01-20 Goergen Nilsson Metod att utföra in vivo-dosimetri vid IMRT-behandling
US7289599B2 (en) 2002-10-04 2007-10-30 Varian Medical Systems Technologies, Inc. Radiation process and apparatus
US7657304B2 (en) 2002-10-05 2010-02-02 Varian Medical Systems, Inc. Imaging device for radiation treatment applications
US7945021B2 (en) 2002-12-18 2011-05-17 Varian Medical Systems, Inc. Multi-mode cone beam CT radiotherapy simulator and treatment machine with a flat panel imager
US7142634B2 (en) 2003-01-29 2006-11-28 New England Medical Center Hospitals, Inc. Radiation field detection
JP3748433B2 (ja) 2003-03-05 2006-02-22 株式会社日立製作所 ベッド位置決め装置及びその位置決め方法
WO2004105574A2 (en) 2003-05-21 2004-12-09 William Beaumont Hospital Image guided radiation therapy
US7513861B2 (en) 2003-06-18 2009-04-07 Xoft, Inc. Real time verification in radiation treatment
US7412029B2 (en) 2003-06-25 2008-08-12 Varian Medical Systems Technologies, Inc. Treatment planning, simulation, and verification system
US7412280B2 (en) 2003-07-01 2008-08-12 Ge Medical Systems Global Technology Company, Llc Systems and methods for analyzing an abnormality of an object
US7266175B1 (en) 2003-07-11 2007-09-04 Nomos Corporation Planning method for radiation therapy
US7343030B2 (en) 2003-08-05 2008-03-11 Imquant, Inc. Dynamic tumor treatment system
WO2005018742A1 (en) 2003-08-11 2005-03-03 Nomos Corporation Method and aparatus for optimization of collimator angles in intensity modulated radiation therapy treatment
AU2004266644B2 (en) 2003-08-12 2009-07-16 Vision Rt Limited Patient positioning system for radiation therapy system
CA2967536C (en) 2003-08-12 2020-08-25 Vision Rt Limited Patient positioning system for radiation therapy system
WO2005031629A1 (en) 2003-09-29 2005-04-07 Koninklijke Philips Electronics, N.V. Method and device for planning a radiation therapy
JP2007509644A (ja) 2003-10-07 2007-04-19 ノモス・コーポレーシヨン 等角放射線治療のための計画システム、方法及び装置
US7068750B2 (en) 2003-10-27 2006-06-27 General Electric Company System and method of x-ray flux management control
US20050111757A1 (en) 2003-11-26 2005-05-26 Brackett Charles C. Auto-image alignment system and method based on identified anomalies
US7492931B2 (en) 2003-11-26 2009-02-17 Ge Medical Systems Global Technology Company, Llc Image temporal change detection and display method and apparatus
WO2005072825A1 (en) 2004-01-20 2005-08-11 University Of Florida Research Foundation, Inc. Radiation therapy system using interior-point methods and convex models for intensity modulated fluence map optimization
JP5110881B2 (ja) 2004-02-20 2012-12-26 ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイティド 軟組織を同時に画像化しながら等角放射線治療を送達するためのシステム
DE102004039191B4 (de) 2004-08-12 2007-09-27 Siemens Ag Verfahren und Vorrichtung zur Ermittlung und Überwachung von Parametern einer Bestrahlungstherapie
US7302038B2 (en) 2004-09-24 2007-11-27 Wisconsin Alumni Research Foundation Correction of patient rotation errors in radiotherapy using couch translation
US7508967B2 (en) 2004-10-14 2009-03-24 Wisconsin Alumni Research Foundation Radiation treatment planning using conformal avoidance
US8260013B2 (en) 2004-11-22 2012-09-04 Koninklijke Philips Electronics N.V. Data representation for rtp
US7265356B2 (en) 2004-11-29 2007-09-04 The University Of Chicago Image-guided medical intervention apparatus and method
US7349730B2 (en) 2005-01-11 2008-03-25 Moshe Ein-Gal Radiation modulator positioner
DE102005007851A1 (de) * 2005-02-21 2006-08-24 Siemens Ag Bestrahlungsvorrichtung
US20070003010A1 (en) 2005-04-29 2007-01-04 Varian Medical Systems Technologies, Inc. Radiation systems with imaging capability
US8077936B2 (en) 2005-06-02 2011-12-13 Accuray Incorporated Treatment planning software and corresponding user interface
US7379531B2 (en) 2005-06-13 2008-05-27 Siemens Medical Solutions Health Services Corporation Beam therapy treatment user interface monitoring and recording system
US7362848B2 (en) 2005-06-27 2008-04-22 Accuray Incorporated Method for automatic anatomy-specific treatment planning protocols based on historical integration of previously accepted plans
JP2009502253A (ja) 2005-07-22 2009-01-29 トモセラピー・インコーポレーテッド 関心の移動領域に対して放射線療法を施すシステムおよび方法
AU2006272730A1 (en) 2005-07-22 2007-02-01 Tomotherapy Incorporated Method of and system for predicting dose delivery
EP1906827A4 (en) 2005-07-22 2009-10-21 Tomotherapy Inc SYSTEM AND METHOD FOR EVALUATING A DOSE ADMINISTERED BY A RADIATION THERAPY SYSTEM
US8442287B2 (en) 2005-07-22 2013-05-14 Tomotherapy Incorporated Method and system for evaluating quality assurance criteria in delivery of a treatment plan
US7611452B2 (en) 2005-09-30 2009-11-03 Accuray Incorporated Wizard and template for treatment planning
CN101365963B (zh) 2006-01-09 2012-02-01 皇家飞利浦电子股份有限公司 构建飞行时间pet图像的方法
JP5254810B2 (ja) 2006-02-28 2013-08-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ リストモードデータに基づく局所動き補償
JP2009538195A (ja) 2006-05-25 2009-11-05 ウィリアム・ボーモント・ホスピタル 立体画像誘導による適応放射線療法のための実時間オンライン及びオフライン治療線量追跡並びにフィードバックプロセス
US7693257B2 (en) 2006-06-29 2010-04-06 Accuray Incorporated Treatment delivery optimization
EP2051775A4 (en) 2006-07-27 2012-08-22 British Columbia Cancer Agency SYSTEMS AND METHODS FOR OPTIMIZING ADAPTIVE ONLINE RADIOTHERAPY
EP2064641A1 (en) 2006-08-01 2009-06-03 Koninklijke Philips Electronics N.V. Biology guided adaptive therapy planning
DE102006042572A1 (de) 2006-09-11 2008-03-27 Siemens Ag Bildgebende medizinische Einheit
DE102006044139B4 (de) 2006-09-15 2008-10-02 Siemens Ag Strahlentherapieanlage und Verfahren zur Anpassung eines Bestrahlungsfeldes für einen Bestrahlungsvorgang eines zu bestrahlenden Zielvolumens eines Patienten
JP2010517672A (ja) 2007-02-07 2010-05-27 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 数量的データ分析の運動補償及び治療
EP2121135B1 (en) 2007-03-19 2014-12-24 Koninklijke Philips N.V. Treatment optimization
CN101663069A (zh) 2007-03-30 2010-03-03 皇家飞利浦电子股份有限公司 通过随机分析描绘不确定性在放疗中改进治疗计划评价
US8363783B2 (en) 2007-06-04 2013-01-29 Oraya Therapeutics, Inc. Method and device for ocular alignment and coupling of ocular structures
DE102007039454B4 (de) 2007-08-21 2016-07-28 Siemens Healthcare Gmbh Verfahren zur Quantifizierung der Aufnahme wenigstens eines Radiotracers in einem für eine Positronen-Emissions-Tomograpie-Messung interessierenden Körperbereich eines Patienten
JP2011502010A (ja) 2007-10-25 2011-01-20 トモセラピー・インコーポレーテッド 放射線療法送達の運動適応最適化のためのシステム及び方法
US8107589B2 (en) 2007-12-21 2012-01-31 Kabushiki Kaisha Toshiba Radiotherapeutic system and radiotherapeutic dose distribution measuring method
JP5197025B2 (ja) 2008-01-09 2013-05-15 株式会社東芝 放射線治療システム、放射線治療支援装置及び放射線治療支援プログラム
US8017915B2 (en) 2008-03-14 2011-09-13 Reflexion Medical, Inc. Method and apparatus for emission guided radiation therapy
US8019042B2 (en) 2008-04-22 2011-09-13 Siemens Medical Solutions Usa, Inc. Medical imaging processing and care planning system
US7724870B2 (en) 2008-05-30 2010-05-25 Siemens Medical Solutions Usa, Inc. Digital tomosynthesis in robotic stereotactic radiosurgery
US8063376B2 (en) 2008-08-15 2011-11-22 Koninklijke Philips Electronics N.V. Large bore PET and hybrid PET/CT scanners and radiation therapy planning using same
US7817778B2 (en) * 2008-08-29 2010-10-19 Varian Medical Systems International Ag Interactive treatment plan optimization for radiation therapy
US8483803B2 (en) 2008-09-15 2013-07-09 Varian Medical Systems, Inc. Systems and methods for tracking and targeting object in a patient using imaging techniques
US10363437B2 (en) * 2008-12-11 2019-07-30 Varian Medical Systems International Ag Real time treatment parameter algorithm for moving targets
US8278633B2 (en) 2009-01-20 2012-10-02 Varian Medical Systems International Ag Gated radiation procedure using packages
EP2412405B1 (en) 2009-03-24 2015-05-20 National University Corporation Hokkaido University Radiation therapy apparatus
US9268042B2 (en) 2009-08-26 2016-02-23 Varian Medical Systems International Ag Characterizing radiotherapy beams based on image detection array data
US8090074B2 (en) 2009-10-02 2012-01-03 Varian Medical Systems International Ag Systems and methods for obtaining reconstructed images during a treatment session
US8401148B2 (en) * 2009-10-30 2013-03-19 Tomotherapy Incorporated Non-voxel-based broad-beam (NVBB) algorithm for intensity modulated radiation therapy dose calculation and plan optimization
JP5595738B2 (ja) 2010-01-05 2014-09-24 株式会社東芝 核医学診断装置
CN102068763B (zh) 2010-03-23 2013-03-27 北京大基康明医疗设备有限公司 放射处理的验证方法和放射处理装置
EP2585854B1 (en) 2010-06-22 2020-03-18 Varian Medical Systems International AG System and method for estimating and manipulating estimated radiation dose
US8816307B2 (en) 2010-07-15 2014-08-26 Varian Medical Systems International Ag Method and apparatus pertaining to use of jaws during radiation treatment
JP5714438B2 (ja) 2010-07-15 2015-05-07 株式会社東芝 放射線治療システム及びその作動方法
EP2598205B1 (en) * 2010-07-29 2016-08-31 Insightec Ltd. Motion compensation for non-invasive treatment therapies
US8605857B1 (en) 2010-12-23 2013-12-10 Math Resolutions, LLC Method and system to reconstruct treatment dose to a patient from integrated exit-transit images of radiation fields taken during treatment
DE102011000204B4 (de) 2011-01-18 2013-04-25 Gsi Helmholtzzentrum Für Schwerionenforschung Gmbh Erstellung einer Bestrahlungsplanung unter Berücksichtigung der Auswirkungen zumindest einer Unsicherheit
WO2013105994A2 (en) 2011-03-07 2013-07-18 Sloan-Kettering Institute For Cancer Research Multi-source radiation system and method for interwoven radiotherapy and imaging
BR112013023264A2 (pt) 2011-03-15 2018-07-03 Koninklijke Philips Nv sistema de planejamento de tratamento para a geração de margens de tratamento específico do paciente, método e sistema de terapia por radiação.
US9956429B2 (en) 2011-03-28 2018-05-01 Varian Medical Systems International Ag Method and system for automated evaluation of multiple portal dose images in radiation therapy
CN103650095B (zh) * 2011-03-31 2016-12-07 反射医疗公司 用于在发射引导的放射治疗中使用的系统和方法
US20120292534A1 (en) 2011-05-20 2012-11-22 Sarah Geneser Multi-phase Gating for Radiation Treatment Delivery and Imaging
MX2014001659A (es) 2011-08-16 2014-03-31 Koninkl Philips Nv Metodo para estimar el movimiento de un organo interfraccional e interfraccional para radioterapia de haces externos adaptativos.
JP5889585B2 (ja) 2011-09-15 2016-03-22 株式会社東芝 放射線治療情報生成装置
US8836697B2 (en) 2011-09-30 2014-09-16 Varian Medical Systems International Ag Real-time 3D dose visualization system
MX2014003685A (es) 2011-09-30 2015-05-11 Childrens Hosp Medical Center Metodo para optimizacion coherente y verificable de una dosis de radiacion de tomografia computarizada (tc).
CN103945901A (zh) 2011-10-14 2014-07-23 住友重机械工业株式会社 带电粒子束照射系统以及带电粒子束照射计划方法
EP2795496B1 (de) 2011-12-23 2020-08-05 Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. Navigierbare darstellung einer lösungsvielfalt von therapieplänen
EP2664359A1 (en) * 2012-05-14 2013-11-20 Koninklijke Philips N.V. Magnetic resonance guided therapy with interleaved scanning
EP2687259A1 (en) 2012-07-19 2014-01-22 Deutsches Krebsforschungszentrum Leaf module for a multi-leaf collimator and multi-leaf collimator
JP2014023741A (ja) 2012-07-27 2014-02-06 Univ Of Tokushima 強度変調放射線治療計画装置、強度変調放射線照射装置の放射線ビーム係数演算方法、強度変調放射線治療計画プログラム及びコンピュータで読み取り可能な記録媒体並びに記録した機器
FR2996008B1 (fr) 2012-09-26 2016-08-19 Univ Rennes Procede d'evaluation d'une methode de determination de la dose cumulee recue au cours d'un traitement de radiotherapie
CN103845068A (zh) 2012-11-28 2014-06-11 北京大基康明医疗设备有限公司 融合pet-ct功能的高能放射治疗系统
JP2014166245A (ja) 2013-02-28 2014-09-11 Mitsubishi Heavy Ind Ltd 治療計画装置、計画治療システム、治療計画生成方法およびプログラム
US9504850B2 (en) 2013-03-14 2016-11-29 Xcision Medical Systems Llc Methods and system for breathing-synchronized, target-tracking radiation therapy
US9839704B2 (en) 2013-05-02 2017-12-12 Duke University Prosthetic compounds for labeling internalizing biomolecules
CA2951048A1 (en) 2013-06-12 2014-12-18 University Health Network Method and system for automated quality assurance and automated treatment planning in radiation therapy
WO2015008188A1 (en) 2013-07-17 2015-01-22 Koninklijke Philips N.V. Portal imaging for brachytherapy
US10674983B2 (en) 2013-09-25 2020-06-09 Richard R. Black Patient-specific analysis of positron emission tomography data
JP6208535B2 (ja) * 2013-10-25 2017-10-04 株式会社日立製作所 放射線治療装置およびシステムおよび方法
US9265971B2 (en) 2014-02-07 2016-02-23 Varian Medical Systems, Inc. Systems, methods, and devices for real-time treatment verification using an electronic portal imaging device
WO2015168431A1 (en) 2014-04-30 2015-11-05 Stc.Unm Optimization methods for radiation therapy planning
US9604077B2 (en) 2014-06-16 2017-03-28 The Board Of Trustees Of The Leland Stanford Junior University Visualizing radiation therapy beam in real-time in the context of patient's anatomy
US9616251B2 (en) 2014-07-25 2017-04-11 Varian Medical Systems, Inc. Imaging based calibration systems, devices, and methods
US9782607B2 (en) * 2014-08-05 2017-10-10 The University Of Chicago Systems and methods for radiation treatment planning using combined imaging and treatment dose
EP2990078B1 (en) 2014-08-27 2018-07-04 Scandidos AB A position detector
US9950194B2 (en) 2014-09-09 2018-04-24 Mevion Medical Systems, Inc. Patient positioning system
EP3209202B1 (en) 2014-10-20 2024-01-24 New York University Apparatus to select radiation dosage for tumor treatment based on cellular imaging
JP2016168077A (ja) 2015-03-11 2016-09-23 三菱電機株式会社 治療計画装置
EP3308381A4 (en) 2015-06-10 2019-04-17 RefleXion Medical Inc. BINARY MULTI-LEAF COLLIMATOR DESIGN WITH HIGH BANDWIDTH
US9943705B2 (en) 2015-06-12 2018-04-17 Accuray Incorporated Verification of leaf positions for multi-leaf collimator using multiple verification systems
US10328282B2 (en) 2015-07-13 2019-06-25 Mayo Foundation For Medical Education And Research System and method for novel chance-constrained optimization in intensity-modulated proton therapy planning to account for range and patient setup uncertainties
US9841387B2 (en) 2015-07-22 2017-12-12 Test Research, Inc. Inspection method and device
US9884206B2 (en) 2015-07-23 2018-02-06 Loma Linda University Medical Center Systems and methods for intensity modulated radiation therapy
US10702708B2 (en) * 2015-09-25 2020-07-07 Varian Medical Systems, Inc. Accounting for imaging-based radiation doses
US10729920B2 (en) 2015-10-02 2020-08-04 Varian Medical Systems International Ag Systems and methods for quantifying radiation beam conformity
WO2017081768A1 (ja) 2015-11-11 2017-05-18 三菱電機株式会社 粒子線治療装置及び治療計画補正方法
GB2544767B (en) 2015-11-25 2018-02-28 Elekta ltd Managing radiotherapy systems
WO2017156316A1 (en) 2016-03-09 2017-09-14 Reflexion Medical, Inc. Fluence map generation methods for radiotherapy
CN117339120A (zh) 2016-11-15 2024-01-05 反射医疗公司 用于发射引导式高能光子传输的系统
WO2018183748A1 (en) 2017-03-30 2018-10-04 Reflexion Medical, Inc. Radiation therapy systems and methods with tumor tracking
EP3384961B1 (en) 2017-04-05 2021-10-13 RaySearch Laboratories AB System and method for modelling of dose calculation in radiotherapy treatment planning
CN110997063B (zh) 2017-05-30 2022-04-29 反射医疗公司 用于计算放射注量的方法的放射治疗系统
US11648418B2 (en) 2017-06-22 2023-05-16 Reflexion Medical, Inc. Systems and methods for biological adaptive radiotherapy
US10456600B2 (en) 2017-07-26 2019-10-29 Reflexion Medical, Inc. Graphical representation of radiation therapy
CN114401674B (zh) 2019-07-12 2025-03-11 反射医疗公司 放射治疗的多靶治疗计划和递送以及虚拟定位

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060159220A1 (en) 2003-07-15 2006-07-20 Heuscher Dominic J Computed tomograhpy with large gantry bore
JP2012506734A (ja) 2008-10-27 2012-03-22 トモセラピー・インコーポレーテッド 放射線療法デリバリ用の運動適応最適化システムおよび方法
US20130188856A1 (en) 2011-12-01 2013-07-25 Varian Medical Systems, Inc. Systems and methods for real-time target validation for image-guided radiation therapy
WO2016023786A1 (en) 2014-08-15 2016-02-18 Koninklijke Philips N.V. Supervised 4-d dose map deformation for adaptive radiotherapy planning

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