JP4509115B2 - 放射線治療を計画するための方法及び装置 - Google Patents
放射線治療を計画するための方法及び装置 Download PDFInfo
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- JP4509115B2 JP4509115B2 JP2006527527A JP2006527527A JP4509115B2 JP 4509115 B2 JP4509115 B2 JP 4509115B2 JP 2006527527 A JP2006527527 A JP 2006527527A JP 2006527527 A JP2006527527 A JP 2006527527A JP 4509115 B2 JP4509115 B2 JP 4509115B2
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- 238000001959 radiotherapy Methods 0.000 title claims abstract description 36
- 238000000034 method Methods 0.000 title claims abstract description 32
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- 230000005855 radiation Effects 0.000 claims abstract description 19
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- 231100001261 hazardous Toxicity 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/50—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
- A61N2005/1055—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using magnetic resonance imaging [MRI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
- A61N2005/1061—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
- A61N5/1065—Beam adjustment
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Primary Health Care (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Urology & Nephrology (AREA)
- Data Mining & Analysis (AREA)
- Databases & Information Systems (AREA)
- Radiation-Therapy Devices (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Description
E=Eext+αEint
を最小化することにより達成される。Eextは、外部エネルギーを表し、これは、事前に検出した表面パッチに向けて前記メッシュを動かす。Eintは内部エネルギーを表し、内部エネルギーはメッシュの柔軟性を制限する。αは各項の相対的な影響に重みを供給する。
での画像勾配に垂直な平面により引き寄せられることができる。
は、表面メッシュを使用することにより決められる境界における所定の変位である。有限要素法による体積メッシュに関する上記公式の打ち切り(discretization)は、等式の線形系となる。所定の変位は、結果生じる体積変形を強いるための境界条件として前記線形系に含まれることができる。本発明の態様によれば、これら境界条件は表面1と表面2との間にあるポイントの相関性に対応する。
Claims (4)
- −第1及び第2の画像を記憶するためのメモリ、及び
−プロセッサ、
を有する放射線治療計画装置において、前記プロセッサは、
−前記第1の画像に基づいて標的体積に対する線量分布を決めるステップ、
−前記第1の画像における前記標的体積の対象となる物体に第1の表面メッシュを当てるステップ、
−前記第1の表面メッシュを前記第1の画像における前記対象となる物体の表面に対し第1の適合を行い、第2の表面メッシュを生じさせるステップ、
−前記第2の画像における前記対象となる物体に前記第2の表面メッシュを当てるステップ、
−前記第2の表面メッシュを前記第2の画像における前記対象となる物体の表面に対し第2の適合を行い、第3の表面メッシュを生じさせるステップ、
−前記第2の表面メッシュと前記第3の表面メッシュとの差を得るステップ、
−前記第2の表面メッシュに基づいて前記対象となる物体の体積モデルを生成するステップ、
−前記差に基づいて前記体積モデルを変形させ、変形した体積モデルを生じさせるステップ、及び
−前記変形した体積モデルに基づいて、前記線量分布を調節するステップ、
を実行するのに適し、前記第1及び第2の画像は放射線治療処理の異なる時点で撮られている装置。 - 前記差は前記体積モデルの変形に対する境界条件として用いられ、生物化学モデルが前記体積モデルの変形において考慮される請求項1に記載の放射線治療計画装置。
- 前記第1及び第2の画像はCT画像である請求項1に記載の放射線治療計画装置。
- 放射線治療計画装置用のコンピュータプログラムであり、前記放射線治療計画装置のプロセッサは、前記コンピュータプログラムが前記プロセッサにおいて実行される場合、
−第1の画像に基づいて標的体積に対する線量分布を決めるステップ、
−前記第1の画像における前記標的体積の対象となる物体に第1の表面メッシュを当てるステップ、
−前記第1の表面メッシュを前記第1の画像における前記対象となる物体の表面に対し第1の適合を行い、第2の表面メッシュを生じさせるステップ、
−前記第2の画像における前記対象となる物体に前記第2の表面メッシュを当てるステップ、
−前記第2の表面メッシュを前記第2の画像における前記対象となる物体の表面に対し第2の適合を行い、第3の表面メッシュを生じさせるステップ、
−前記第2の表面メッシュと前記第3の表面メッシュとの差を得るステップ、
−前記第2の表面メッシュに基づいて前記対象となる物体の体積モデルを生成するステップ、
−前記差に基づいて前記体積モデルを変形させ、変形した体積モデルを生じさせるステップ、及び
−前記変形した体積モデルに基づいて、前記線量分布を調節するステップ
を行い、前記第1及び第2の画像は放射線治療処理の異なる時点で撮られているコンピュータプログラム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50697203P | 2003-09-29 | 2003-09-29 | |
US58483304P | 2004-06-30 | 2004-06-30 | |
PCT/IB2004/051739 WO2005031629A1 (en) | 2003-09-29 | 2004-09-10 | Method and device for planning a radiation therapy |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2007507249A JP2007507249A (ja) | 2007-03-29 |
JP2007507249A5 JP2007507249A5 (ja) | 2007-11-08 |
JP4509115B2 true JP4509115B2 (ja) | 2010-07-21 |
Family
ID=34396330
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006527527A Expired - Fee Related JP4509115B2 (ja) | 2003-09-29 | 2004-09-10 | 放射線治療を計画するための方法及び装置 |
Country Status (6)
Country | Link |
---|---|
US (1) | US7708682B2 (ja) |
EP (1) | EP1671252B1 (ja) |
JP (1) | JP4509115B2 (ja) |
AT (1) | ATE408198T1 (ja) |
DE (1) | DE602004016540D1 (ja) |
WO (1) | WO2005031629A1 (ja) |
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- 2004-09-10 JP JP2006527527A patent/JP4509115B2/ja not_active Expired - Fee Related
- 2004-09-10 WO PCT/IB2004/051739 patent/WO2005031629A1/en active IP Right Grant
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ATE408198T1 (de) | 2008-09-15 |
US7708682B2 (en) | 2010-05-04 |
EP1671252A1 (en) | 2006-06-21 |
US20070049785A1 (en) | 2007-03-01 |
DE602004016540D1 (de) | 2008-10-23 |
WO2005031629A1 (en) | 2005-04-07 |
JP2007507249A (ja) | 2007-03-29 |
EP1671252B1 (en) | 2008-09-10 |
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