JP7483810B2 - ６－アミノピラゾロピリミジン化合物及びその医薬用途 - Google Patents

６－アミノピラゾロピリミジン化合物及びその医薬用途 Download PDF

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JP7483810B2
JP7483810B2 JP2022136673A JP2022136673A JP7483810B2 JP 7483810 B2 JP7483810 B2 JP 7483810B2 JP 2022136673 A JP2022136673 A JP 2022136673A JP 2022136673 A JP2022136673 A JP 2022136673A JP 7483810 B2 JP7483810 B2 JP 7483810B2
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alkoxy
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JP2023036007A (ja
JP2023036007A5 (enExample
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雄介 大場
馨 足達
達也 西丸
健太朗 櫻井
洋介 生越
晋平 佐藤
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Japan Tobacco Inc
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Japan Tobacco Inc
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    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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JP2022136673A 2021-08-31 2022-08-30 ６－アミノピラゾロピリミジン化合物及びその医薬用途 Active JP7483810B2 (ja)

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TW202416965A (zh) * 2022-08-29 2024-05-01 日商日本煙草產業股份有限公司 吡唑并嘧啶化合物及其醫藥用途
WO2024177126A1 (ja) * 2023-02-24 2024-08-29 日本たばこ産業株式会社 ６－アルコキシピラゾロピリミジン化合物及びその医薬用途
KR20250151389A (ko) * 2023-02-24 2025-10-21 니뽄 다바코 산교 가부시키가이샤 치환 피라졸로피리미딘 화합물 및 그의 의약 용도
KR20250170647A (ko) 2023-04-14 2025-12-05 다케다 야쿠힌 고교 가부시키가이샤 Nlrp3 억제제로서의 피라졸로피리미딘 유도체
WO2024249539A1 (en) 2023-06-02 2024-12-05 Merck Sharp & Dohme Llc 5,6 unsaturated bicyclic heterocyles useful as inhibitors of nod-like receptor protein 3
TW202535370A (zh) * 2023-12-14 2025-09-16 美商默沙東有限責任公司 作為nod樣受體蛋白3抑制劑之吲唑衍生物
WO2025128781A1 (en) * 2023-12-14 2025-06-19 Merck Sharp & Dohme Llc Azaindazole derivatives useful as inhibitors of nod-like receptor protein 3
CN120230110A (zh) * 2023-12-31 2025-07-01 杭州百新生物医药科技有限公司 吡唑并嘧啶类化合物及其医药用途
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