JP7466905B2 - 二段階相同組換え修復によるスカーレスゲノム編集 - Google Patents

二段階相同組換え修復によるスカーレスゲノム編集 Download PDF

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JP7466905B2
JP7466905B2 JP2020502409A JP2020502409A JP7466905B2 JP 7466905 B2 JP7466905 B2 JP 7466905B2 JP 2020502409 A JP2020502409 A JP 2020502409A JP 2020502409 A JP2020502409 A JP 2020502409A JP 7466905 B2 JP7466905 B2 JP 7466905B2
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cell
cells
cas9
sequence
donor polynucleotide
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JP2020532291A (ja
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和哉 池田
マシュー エイチ． ポルテウス
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Leland Stanford Junior University
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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JP2020502409A 2017-07-18 2018-07-18 二段階相同組換え修復によるスカーレスゲノム編集 Active JP7466905B2 (ja)

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WO2019018534A1 (en) 2017-07-18 2019-01-24 The Board Of Trustees Of Leland Stanford Junior University GENOME EDITION WITHOUT SCARCE THROUGH TWO-STEP APPROVED REPAIR BY HOMOLOGY
KR102487901B1 (ko) 2019-04-04 2023-01-12 리제너론 파마슈티칼스 인코포레이티드 표적화된 변형의 표적화 벡터로의 무흔적 도입을 위한 방법
CN113151339B (zh) * 2020-01-23 2022-07-01 中国科学院大连化学物理研究所 一种基因突变表达盒及其应用
JPWO2021206054A1 (enExample) * 2020-04-06 2021-10-14
US11214811B1 (en) 2020-07-31 2022-01-04 Inari Agriculture Technology, Inc. INIR6 transgenic maize
EP4172342A4 (en) * 2020-07-31 2024-10-02 Inari Agriculture Technology, Inc. REMOVABLE TRANSGENIC PLANT LOCI WITH RELATED RNA GUIDE RECOGNITION SITES
US20240011043A1 (en) 2020-07-31 2024-01-11 Inari Agriculture Technology, Inc. Generation of plants with improved transgenic loci by genome editing
WO2022026379A1 (en) * 2020-07-31 2022-02-03 Inari Agriculture Technology, Inc. Expedited breeding of transgenic crop plants by genome editing
CN118056013A (zh) * 2021-08-31 2024-05-17 纽约大学 用于逐步转换抗生素抗性标记以进行整合（mSwAP-In）的组合物和方法
JP2024533683A (ja) * 2021-09-24 2024-09-12 イムノカン バイオテック カンパニー リミテッド 大型染色体の導入方法と改変染色体およびそれを用いた生物
WO2024020596A1 (en) * 2022-07-22 2024-01-25 Villanova University Methods and compositions comprising fusion proteins for the identification of immunotherapy cells
WO2024263652A1 (en) * 2023-06-19 2024-12-26 The Regents Of The University Of California Compositions for and methods of tagging endogenously expressed proteins
IT202300019377A1 (it) * 2023-09-20 2025-03-20 Univ Degli Studi Di Pavia Linee di cellule staminali contenenti proteine endogene marcate con espressione differenziale, metodi di produzione e loro utilizzo per l’identificazione del ciclo cellulare
WO2025126797A1 (ja) * 2023-12-13 2025-06-19 国立大学法人 東京大学 高効率な長鎖核酸配列の部位特異的ノックイン法
WO2025182957A1 (ja) * 2024-02-26 2025-09-04 株式会社ニチレイフーズ 改変ｄｎａを含む細胞の作製方法、該細胞を含む生物体の作製方法、及び遺伝子産物の生産方法

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WO2019018534A1 (en) 2017-07-18 2019-01-24 The Board Of Trustees Of Leland Stanford Junior University GENOME EDITION WITHOUT SCARCE THROUGH TWO-STEP APPROVED REPAIR BY HOMOLOGY

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US20200208172A1 (en) 2020-07-02
WO2019018534A8 (en) 2020-02-20
US11692202B2 (en) 2023-07-04
US12442016B2 (en) 2025-10-14
JP2020532291A (ja) 2020-11-12
WO2019018534A1 (en) 2019-01-24
US20230348932A1 (en) 2023-11-02

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