JP7455801B2 - ピストン位置の検出に基づいて制御されるピペットピストン運動を用いた、パルス状ピペッティングのための分注装置 - Google Patents

ピストン位置の検出に基づいて制御されるピペットピストン運動を用いた、パルス状ピペッティングのための分注装置 Download PDF

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JP7455801B2
JP7455801B2 JP2021500610A JP2021500610A JP7455801B2 JP 7455801 B2 JP7455801 B2 JP 7455801B2 JP 2021500610 A JP2021500610 A JP 2021500610A JP 2021500610 A JP2021500610 A JP 2021500610A JP 7455801 B2 JP7455801 B2 JP 7455801B2
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pipette
piston
dispensing
liquid
volume
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JP2021524376A (ja
JP2021524376A5 (https=
JPWO2020011787A5 (https=
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ハンスペーター・ローマー
レト・エッティンガー
フリードリーン・ギゼル
ユルク・ラスト
ヨナス・ヒルティ
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ハミルトン・ボナドゥーツ・アーゲー
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0227Details of motor drive means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0237Details of electronic control, e.g. relating to user interface
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0241Drop counters; Drop formers
    • B01L3/0268Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011Control of the position or alignment of the transfer device
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016Control of the volume dispensed or introduced
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14Process control and prevention of errors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0663Whole sensors
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1034Transferring microquantities of liquid

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Human Computer Interaction (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
JP2021500610A 2018-07-11 2019-07-09 ピストン位置の検出に基づいて制御されるピペットピストン運動を用いた、パルス状ピペッティングのための分注装置 Active JP7455801B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102018211497.8 2018-07-11
DE102018211497.8A DE102018211497A1 (de) 2018-07-11 2018-07-11 Pipettiervorrichtung zur impulsartigen Pipettierung mit einer basierend auf einer Erfassung des Arbeitsgasdrucks geregelten Pipettierkolbenbewegung
PCT/EP2019/068417 WO2020011787A1 (de) 2018-07-11 2019-07-09 Pipettiervorrichtung zur impulsartigen pipettierung mit einer basierend auf einer erfassung der kolbenposition geregelten pipettierkolbenbewegung

Publications (4)

Publication Number Publication Date
JP2021524376A JP2021524376A (ja) 2021-09-13
JP2021524376A5 JP2021524376A5 (https=) 2022-07-19
JPWO2020011787A5 JPWO2020011787A5 (https=) 2022-07-19
JP7455801B2 true JP7455801B2 (ja) 2024-03-26

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JP2021500610A Active JP7455801B2 (ja) 2018-07-11 2019-07-09 ピストン位置の検出に基づいて制御されるピペットピストン運動を用いた、パルス状ピペッティングのための分注装置

Country Status (6)

Country Link
US (1) US11911757B2 (https=)
EP (1) EP3820614B1 (https=)
JP (1) JP7455801B2 (https=)
CN (1) CN112423886B (https=)
DE (1) DE102018211497A1 (https=)
WO (1) WO2020011787A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11124406B1 (en) * 2014-07-13 2021-09-21 Sestra Systems, Inc. System and method for piston detection in a metering mechanism for use with beverage dispensing system
DE102018125196A1 (de) * 2018-10-11 2020-04-16 Hamilton Bonaduz Ag Vorrichtung und Verfahren zur Qualitätsbestimmung einer impulsartigen Flüssigkeitsdispensation nach dem Air-Displacement-Prinzip
DE102019126731A1 (de) * 2019-10-02 2021-04-08 Hamilton Bonaduz Ag Vorrichtung und Verfahren zum exakten flüssigkeitsklassen-unabhängigen Pipettieren
DE102020104422A1 (de) * 2020-02-19 2021-08-19 Hamilton Bonaduz Ag Verfahren zur Zuordnung einer Pipettierspitze zu einer Pipettierspitzenklasse aufgrund ihres pneumatischen Verhaltens
JP7357787B2 (ja) * 2020-05-29 2023-10-06 株式会社日立ハイテク 自動分析装置の制御方法
US11559823B2 (en) * 2020-09-18 2023-01-24 Asmpt Singapore Pte. Ltd. Volumetric measurement and regulation device incorporated in a time-pressure dispenser
CN116832891A (zh) * 2023-08-10 2023-10-03 上海镁伽智能科技有限公司 用于移液装置的变距方法、变距控制装置及移液设备

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006132984A (ja) 2004-11-02 2006-05-25 Sumitomo Heavy Ind Ltd 放射性液体の分注方法及び分注装置
JP2008197037A (ja) 2007-02-15 2008-08-28 Yaskawa Electric Corp 分注装置およびそのコントローラと分注方法
WO2013094373A1 (ja) 2011-12-22 2013-06-27 三洋電機株式会社 分注装置
WO2017017084A1 (de) 2015-07-30 2017-02-02 Hamilton Bonaduz Ag Pipettiervorrichtung zur pipettierung kleiner flüssigkeitsvolumina
WO2018108825A1 (de) 2016-12-15 2018-06-21 Hamilton Bonaduz Ag Pipettiervorrichtung zur verbesserten impulsartigen flüssigkeitspipettierung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3750460B2 (ja) 2000-02-18 2006-03-01 日立工機株式会社 分注装置及び分注方法
JP2012510065A (ja) * 2008-11-28 2012-04-26 ハミルトン・ボナドゥーツ・アーゲー 極小の測定体積の測定に適した測定デバイス、及び測定方法
DE102010000690A1 (de) * 2010-01-05 2011-07-07 Hamilton Bonaduz Ag Dosiervorrichtung und Dosierverfahren
DE102012214677A1 (de) * 2012-08-17 2014-02-20 Hamilton Bonaduz Ag Pipette mit elektromotorisch angetriebenem Kolben und Magnetfeldabschirmung
DE102017201114A1 (de) * 2017-01-24 2018-07-26 Hamilton Bonaduz Ag Pipettiervorrichtung zur impulsartigen Pipettierung mit einer basierend auf einer Erfassung des Arbeitsgasdrucks geregelten Pipettierkolbenbewegung
EP3434373A1 (de) * 2017-07-27 2019-01-30 Eppendorf AG Pipettiervorrichtung mit funktionsprüfung und verfahren zur funktionsprüfung einer pipettiervorrichtung

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006132984A (ja) 2004-11-02 2006-05-25 Sumitomo Heavy Ind Ltd 放射性液体の分注方法及び分注装置
JP2008197037A (ja) 2007-02-15 2008-08-28 Yaskawa Electric Corp 分注装置およびそのコントローラと分注方法
WO2013094373A1 (ja) 2011-12-22 2013-06-27 三洋電機株式会社 分注装置
WO2017017084A1 (de) 2015-07-30 2017-02-02 Hamilton Bonaduz Ag Pipettiervorrichtung zur pipettierung kleiner flüssigkeitsvolumina
JP2018523120A (ja) 2015-07-30 2018-08-16 ハミルトン・ボナドゥーツ・アーゲー 少量の液体を分注するための分注装置
WO2018108825A1 (de) 2016-12-15 2018-06-21 Hamilton Bonaduz Ag Pipettiervorrichtung zur verbesserten impulsartigen flüssigkeitspipettierung
JP2020514015A (ja) 2016-12-15 2020-05-21 ハミルトン・ボナドゥーツ・アーゲー 改善されたパルス状液体ピペッティングのためのピペット装置

Also Published As

Publication number Publication date
EP3820614B1 (de) 2024-11-13
EP3820614A1 (de) 2021-05-19
JP2021524376A (ja) 2021-09-13
CN112423886B (zh) 2023-03-07
CN112423886A (zh) 2021-02-26
US20210154659A1 (en) 2021-05-27
WO2020011787A1 (de) 2020-01-16
US11911757B2 (en) 2024-02-27
DE102018211497A1 (de) 2020-01-16

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