JP7450269B2 - 灌流可能なバイオリアクタ - Google Patents

灌流可能なバイオリアクタ Download PDF

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Publication number
JP7450269B2
JP7450269B2 JP2020564794A JP2020564794A JP7450269B2 JP 7450269 B2 JP7450269 B2 JP 7450269B2 JP 2020564794 A JP2020564794 A JP 2020564794A JP 2020564794 A JP2020564794 A JP 2020564794A JP 7450269 B2 JP7450269 B2 JP 7450269B2
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medium
bioreactor
collection chamber
liquid
chamber
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JP2021513363A (ja
JPWO2019157356A5 (https=
JP2021513363A5 (https=
Inventor
グレゴリー ソーヤー，ウォレス
ローレン マーシャル，サマンサ
オー． マギー，エリック
マギー，アレクサンダー
メーター，カイリー ヴァン
アテナ ピテニス，アンジェラ
マヌエル ウルエナ，ジュアン
エル． フード，デレク
ドハティ，マイケル
ジョビン，クリスチャン
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ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2521/00—Culture process characterised by the use of hydrostatic pressure, flow or shear forces

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2020564794A 2018-02-08 2019-02-08 灌流可能なバイオリアクタ Active JP7450269B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862628011P 2018-02-08 2018-02-08
US62/628,011 2018-02-08
US201862756732P 2018-11-07 2018-11-07
US62/756,732 2018-11-07
PCT/US2019/017316 WO2019157356A1 (en) 2018-02-08 2019-02-08 Perfusion enabled bioreactors

Publications (4)

Publication Number Publication Date
JP2021513363A JP2021513363A (ja) 2021-05-27
JPWO2019157356A5 JPWO2019157356A5 (https=) 2022-02-04
JP2021513363A5 JP2021513363A5 (https=) 2022-02-04
JP7450269B2 true JP7450269B2 (ja) 2024-03-15

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JP2020564794A Active JP7450269B2 (ja) 2018-02-08 2019-02-08 灌流可能なバイオリアクタ

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EP (1) EP3749335B1 (https=)
JP (1) JP7450269B2 (https=)
CN (1) CN112041422A (https=)
WO (1) WO2019157356A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020074698A (ja) * 2018-11-06 2020-05-21 国立大学法人 東京大学 灌流培養システム及び培養方法
NL2025320B1 (en) * 2020-04-09 2021-10-25 Univ Twente Fluidic device, cell culturing system and method of testing a compound
US20230272327A1 (en) * 2020-07-02 2023-08-31 University Of Florida Research Foundation, Inc. Perfusion-enabled bioreactor
US20240368518A1 (en) * 2021-05-30 2024-11-07 University Of Florida Research Foundation, Inc. Devices, systems, and methods relating to pressurized perfusion-enabled bio-reactors
PL249320B1 (pl) * 2023-01-23 2026-03-23 Politechnika Warszawska Urządzenie do automatycznego precyzyjnego powtarzalnego dozowania odczynników
CN117625394B (zh) * 2023-12-01 2024-12-06 东莞合安机电有限公司 一种荔枝菌菌种培养液、制备方法及培养方法
CN118086053B (zh) * 2024-04-29 2024-07-09 四川迪亚生物科技集团有限公司 一种自灌流培养板及使用方法
CN119425839A (zh) * 2024-11-15 2025-02-14 广州洁特生物过滤股份有限公司 一种负压超滤离心管装置

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Publication number Priority date Publication date Assignee Title
JP2007537759A (ja) 2004-05-19 2007-12-27 マサチューセッツ・インスティテュート・オブ・テクノロジー 灌流三次元細胞／組織疾患モデル
JP2008513013A (ja) 2004-09-16 2008-05-01 ベクトン・ディキンソン・アンド・カンパニー 細胞培養用の潅流バイオリアクタ
WO2016182969A1 (en) 2015-05-08 2016-11-17 University Of Florida Research Foundation, Inc. Growth media for three-dimensional cell culture

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US3940A (en) 1845-03-12 Improvement in piano-fortes
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US2533635A (en) 1947-09-26 1950-12-12 Monsanto Chemicals Printing textile fabrics with a dye paste comprising a styrene-maleic anhydride copolymer cross-linked with divinyl benzene
US3940351A (en) 1974-07-02 1976-02-24 The B. F. Goodrich Company Polymerization of carboxylic acid monomers and alkyl acrylate esters in chlorofluoroethane
US4062817A (en) 1977-04-04 1977-12-13 The B.F. Goodrich Company Water absorbent polymers comprising unsaturated carboxylic acid, acrylic ester containing alkyl group 10-30 carbon atoms, and another acrylic ester containing alkyl group 2-8 carbon atoms
US5034488A (en) 1990-01-11 1991-07-23 Gaf Chemicals Corporation Slurry polymerization of crosslinked maleic anhydride-alkyl vinyl ether copolymers in a solvent system comprising a carboxylic acid ester and a saturated hydrocarbon
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CN203048951U (zh) * 2013-01-24 2013-07-10 中山大学 嵌入式多细胞共培养装置
CN103194390B (zh) * 2013-04-19 2014-08-06 南方医科大学南方医院 双环路振荡灌注式生物反应系统
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Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
JP2007537759A (ja) 2004-05-19 2007-12-27 マサチューセッツ・インスティテュート・オブ・テクノロジー 灌流三次元細胞／組織疾患モデル
JP2008513013A (ja) 2004-09-16 2008-05-01 ベクトン・ディキンソン・アンド・カンパニー 細胞培養用の潅流バイオリアクタ
WO2016182969A1 (en) 2015-05-08 2016-11-17 University Of Florida Research Foundation, Inc. Growth media for three-dimensional cell culture

Non-Patent Citations (1)

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Also Published As

Publication number Publication date
EP3749335A4 (en) 2021-11-03
EP3749335A1 (en) 2020-12-16
JP2021513363A (ja) 2021-05-27
CN112041422A (zh) 2020-12-04
EP3749335B1 (en) 2025-09-24
WO2019157356A1 (en) 2019-08-15

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