JP7417010B1 - 癌免疫増強用のｖｉｐｒ２アンタゴニストペプチド - Google Patents
癌免疫増強用のｖｉｐｒ２アンタゴニストペプチド Download PDFInfo
- Publication number
- JP7417010B1 JP7417010B1 JP2023542946A JP2023542946A JP7417010B1 JP 7417010 B1 JP7417010 B1 JP 7417010B1 JP 2023542946 A JP2023542946 A JP 2023542946A JP 2023542946 A JP2023542946 A JP 2023542946A JP 7417010 B1 JP7417010 B1 JP 7417010B1
- Authority
- JP
- Japan
- Prior art keywords
- vipr2
- cells
- peptide
- tumor
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022057810 | 2022-03-31 | ||
| JP2022057810 | 2022-03-31 | ||
| PCT/JP2023/013061 WO2023190812A1 (ja) | 2022-03-31 | 2023-03-30 | 癌免疫増強用のｖｉｐｒ２アンタゴニストペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPWO2023190812A1 JPWO2023190812A1 (https=) | 2023-10-05 |
| JP7417010B1 true JP7417010B1 (ja) | 2024-01-17 |
| JPWO2023190812A5 JPWO2023190812A5 (https=) | 2024-03-08 |
Family
ID=88202732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023542946A Active JP7417010B1 (ja) | 2022-03-31 | 2023-03-30 | 癌免疫増強用のｖｉｐｒ２アンタゴニストペプチド |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP7417010B1 (https=) |
| WO (1) | WO2023190812A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4137502A4 (en) * | 2020-03-30 | 2024-02-28 | Ichimaru Pharcos Co., Ltd. | Vipr2 antagonist peptide |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021200259A1 (ja) * | 2020-03-30 | 2021-10-07 | 一丸ファルコス株式会社 | Ｖｉｐｒ２アンタゴニストペプチド |
-
2023
- 2023-03-30 JP JP2023542946A patent/JP7417010B1/ja active Active
- 2023-03-30 WO PCT/JP2023/013061 patent/WO2023190812A1/ja not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021200259A1 (ja) * | 2020-03-30 | 2021-10-07 | 一丸ファルコス株式会社 | Ｖｉｐｒ２アンタゴニストペプチド |
Non-Patent Citations (8)
| Title |
|---|
| FNU, T.P. et al.，Inhibition of Vasoactive Intestinal Peptide Signaling with More Potent Inhibitors Augments T-Cell Ac，Blood，2021年11月，Vol.136 Suppl.1，p.1868-1870 |
| FNU, T.P. ET AL.: "Inhibition of Vasoactive Intestinal Peptide Signaling with More Potent Inhibitors Augments T-Cell Ac", BLOOD, vol. Vol.136 Suppl.1, JPN6023023504, November 2021 (2021-11-01), pages 1868 - 1870, ISSN: 0005159866 * |
| KITTIKULSUTH, W. et al.，Vasoactive intestinal peptide blockade suppresses tumor growth by regulating macrophage polarization，Sci. Rep.，2023年01月17日，Vol.13，Article number: 927 |
| KITTIKULSUTH, W. ET AL.: "Vasoactive intestinal peptide blockade suppresses tumor growth by regulating macrophage polarization", SCI. REP., vol. 13, JPN6023023505, 17 January 2023 (2023-01-17), pages 927, ISSN: 0005159868 * |
| MAR, C. et al.，VIP impairs acquisition of the macrophage proinflammatory polarization profile.，J. Leukoc. Biol.，2016年12月，Vol.100 No.6，p.1385-1393 |
| MAR, C. ET AL.: "VIP impairs acquisition of the macrophage proinflammatory polarization profile.", J. LEUKOC. BIOL., vol. 100, no. 6, JPN7023002201, December 2016 (2016-12-01), pages 1385 - 1393, XP093098052, ISSN: 0005159867, DOI: 10.1189/jlb.3A0116-032RR * |
| RAVINDRANATHAN, S. et al.，643 Vasoactive intestinal peptide as a novel immune checkpoint molecule in activated T cells.，J. Immunother. Cancer，2021年11月，Vol.9 Suppl.2，p.A672 |
| RAVINDRANATHAN, S. ET AL.: "643 Vasoactive intestinal peptide as a novel immune checkpoint molecule in activated T cells.", J. IMMUNOTHER. CANCER, vol. Vol.9 Suppl.2, JPN6023023503, November 2021 (2021-11-01), pages 672, ISSN: 0005159865 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2023190812A1 (https=) | 2023-10-05 |
| WO2023190812A9 (ja) | 2023-11-23 |
| WO2023190812A1 (ja) | 2023-10-05 |
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