JP7411281B2 - 呼気関連アプリケーションを使用した結核およびその他の疾患の診断 - Google Patents

呼気関連アプリケーションを使用した結核およびその他の疾患の診断 Download PDF

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JP7411281B2
JP7411281B2 JP2022512715A JP2022512715A JP7411281B2 JP 7411281 B2 JP7411281 B2 JP 7411281B2 JP 2022512715 A JP2022512715 A JP 2022512715A JP 2022512715 A JP2022512715 A JP 2022512715A JP 7411281 B2 JP7411281 B2 JP 7411281B2
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ブライデン、ウェイン、エイ．
コール、チャールズ、ジェイ．
ウッド、ロビン
チェン、ダペン
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ゼテオ テック、 インク．
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7206—Mass spectrometers interfaced to gas chromatograph
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0833—Measuring rate of oxygen consumption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/091—Measuring volume of inspired or expired gases, e.g. to determine lung capacity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
    • G01N1/2205—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling with filters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B2010/0083—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements for taking gas samples
    • A61B2010/0087—Breath samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/029—Humidity sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/087—Measuring breath flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/025—Gas chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/12—Pulmonary diseases

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2022512715A 2019-08-26 2020-08-26 呼気関連アプリケーションを使用した結核およびその他の疾患の診断 Active JP7411281B2 (ja)

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JP2023212642A JP7640129B2 (ja) 2019-08-26 2023-12-18 呼気エアロゾル粒子を含む凝縮液体サンプルを収集するためのシステム

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US201962891954P 2019-08-26 2019-08-26
US62/891,954 2019-08-26
US202063069120P 2020-08-23 2020-08-23
US63/069,120 2020-08-23
PCT/US2020/048040 WO2021041571A1 (en) 2019-08-26 2020-08-26 Diagnosis of tuberculosis and other diseases using exhaled breath

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JP2023212642A Division JP7640129B2 (ja) 2019-08-26 2023-12-18 呼気エアロゾル粒子を含む凝縮液体サンプルを収集するためのシステム

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JP2022545289A5 JP2022545289A5 (https=) 2023-06-30
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JP2023212642A Active JP7640129B2 (ja) 2019-08-26 2023-12-18 呼気エアロゾル粒子を含む凝縮液体サンプルを収集するためのシステム

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US (3) US20220322963A1 (https=)
EP (1) EP4021294A4 (https=)
JP (2) JP7411281B2 (https=)
KR (2) KR102543496B1 (https=)
CN (2) CN117883121A (https=)
WO (1) WO2021041571A1 (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117883121A (zh) 2019-08-26 2024-04-16 泽特奥科技公司 利用呼出气诊断结核病和其他疾病
CN114585903B (zh) 2019-09-23 2023-08-04 泽特奥科技公司 快速自主检测气溶胶粒子的系统和方法
US12074018B2 (en) 2019-09-23 2024-08-27 Zeteo Tech, Inc. Systems and methods of rapid and autonomous detection of aerosol particles
US12442726B2 (en) 2020-04-19 2025-10-14 John J. Daniels Mask-based testing system for detecting biomarkers in exhaled breath condensate, aerosols and gases
US12369816B2 (en) 2020-04-19 2025-07-29 John J. Daniels Mask-based diagnostic system using exhaled breath condensate
US12533047B2 (en) 2020-04-19 2026-01-27 John J. Daniels Mask-based diagnostic system using exhaled breath condensate
US12031982B2 (en) * 2020-04-19 2024-07-09 John J. Daniels Using exhaled breath condensate for testing for a biomarker of COVID-19
CN115715417A (zh) * 2020-06-17 2023-02-24 里沃恩株式会社 系统、信息处理装置及程序
US20220155280A1 (en) * 2020-11-16 2022-05-19 Koninklijke Fabriek Inventum B.V. Systems and methods for collecting a biological sample from a passenger cabin
KR102652313B1 (ko) * 2021-03-05 2024-03-29 재단법인 아산사회복지재단 호기 응축물 시료를 이용한 세균 메타게놈 분석 방법
US20220386893A1 (en) * 2021-03-31 2022-12-08 Zeteo Tech Inc. Capturing truncated proteoforms in exhaled breath for diagnosis and treatment of diseases
EP4312749A4 (en) * 2021-03-31 2025-07-09 Zeteo Tech Inc DIAGNOSIS OF RESPIRATORY DISEASES BY CAPTURE OF AEROSOLIZED BIOMATERIAL PARTICLES USING FIXED BED SYSTEMS AND METHODS
ES2906212B2 (es) * 2021-04-22 2023-06-22 Univ Valencia Politecnica Biosensor y virusometro de deteccion de patogenos en aire y en muestras liquidas
WO2022248936A2 (en) * 2021-05-28 2022-12-01 Exhalation Technology Ltd Device and method for detecting a component of exhaled breath condensate
GB202110582D0 (en) * 2021-07-22 2021-09-08 Owlstone Med Ltd Breath sampling device
US11897495B2 (en) 2021-08-05 2024-02-13 Hyundai Mobis Co., Ltd. Drunk driving prevention system and method therefor
KR20250067957A (ko) * 2021-10-12 2025-05-15 제테오 테크, 인코포레이티드 호기 호흡을 이용한 결핵 및 기타 질병의 진단
US20240423497A1 (en) * 2021-11-02 2024-12-26 Pexa Ab A device and method for determining a respiratory system infection from exhaled breath
WO2023086823A1 (en) * 2021-11-09 2023-05-19 Quintron Instrument Company, Inc. Apparatus and methods for viral and bacterial breath collection
CN114533037B (zh) * 2022-02-23 2022-11-22 安徽省立医院(中国科学技术大学附属第一医院) 一种基于儿童呼吸气体的疾病检测系统及方法
SE547329C2 (en) * 2022-06-03 2025-07-01 Munkplast Ab Method and system for preparing a breath sample for analysis
JP2025528164A (ja) * 2022-08-11 2025-08-26 ゼテオ テック、 インク． 疾患の診断および治療のための呼気中の切断プロテオフォームの捕捉
CN115350556A (zh) * 2022-08-16 2022-11-18 苏州思萃同位素技术研究所有限公司 Co2呼气试验中呼出co2的处置及回收方法和装置
CN115326972A (zh) * 2022-08-18 2022-11-11 浙江大学 冷凝收集非侵入式测定人体呼出气中糖类的分析装置及方法
CN115326986A (zh) * 2022-08-29 2022-11-11 浙江大学 一种测定人体呼出气中有机酸和阴离子的分析装置及方法
US20240264145A1 (en) * 2023-02-07 2024-08-08 Aleck Alexopoulos Device, method, and system for the rapid detection of the tuberculosis mycobacterium dispersed in air
US20250366717A1 (en) * 2024-05-31 2025-12-04 David Michaeli Non-contact rapid diagnosis of illness by laser, infra red, terahertz and/or uv spectroscopy and analysis of water mixture envelope

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001318069A (ja) 2000-05-10 2001-11-16 Matsushita Electric Ind Co Ltd 呼気ガス分析装置
JP2008501976A (ja) 2004-06-07 2008-01-24 ザ シャーロット‐メクレンバーグ ホスピタル オーソリティ 呼気凝縮液中のリポ多糖体を利用するグラム陰性菌性肺炎の診断
JP2018534955A (ja) 2015-09-15 2018-11-29 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 新生児医療を向上させる方法及び装置
WO2019011750A1 (en) 2017-07-10 2019-01-17 Pexa Ab NEW SYSTEM FOR COLLECTING EXPIRED PARTICLES

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5848608U (ja) 1981-09-24 1983-04-01 極東開発工業株式会社 塵芥圧縮押込装置
JPH09126958A (ja) * 1995-10-30 1997-05-16 Suzuki Motor Corp 呼気採取装置
JPH10227725A (ja) * 1997-02-12 1998-08-25 Suzuki Motor Corp 呼気分析装置
US6062392A (en) 1998-11-13 2000-05-16 Mesosystems Technology, Inc. Micromachined virtual impactor
US6267016B1 (en) 1999-03-10 2001-07-31 Mesosystems Technology, Inc. Impact particulate collector using a rotary impeller for collecting particulates and moving a fluid
US7118537B2 (en) * 2001-04-30 2006-10-10 Respiratory Research, Inc. Method and device for collecting and analyzing exhaled breath
US7364553B2 (en) * 2002-12-20 2008-04-29 Amidex, Inc. Breath aerosol management and collection system
US20050085740A1 (en) * 2003-04-01 2005-04-21 Davis Cristina E. Non-invasive breath analysis using field asymmetric ion mobility spectrometry
AU2004294342A1 (en) * 2003-12-01 2005-06-16 Sierra Medical Technology, Inc. A respiratory monitoring, diagnostic and therapeutic system
US8627821B2 (en) * 2005-01-10 2014-01-14 Pulmatrix, Inc. Method and device for decreasing contamination
JP4564406B2 (ja) 2005-05-25 2010-10-20 株式会社日立製作所 呼気捕集フィルタ、呼気収集装置、呼気分析システムおよび呼気分析方法
US7779840B2 (en) * 2006-06-21 2010-08-24 General Electric Company Ventilator breath condensate sampler and method of collecting a breath condensate sample
CA2701352A1 (en) * 2007-10-02 2009-04-09 Ann-Charlotte Almstrand Collection and measurement of exhaled particles
EP2060919A1 (en) 2007-11-13 2009-05-20 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO MALDI matrix and MALDI method
JP5289837B2 (ja) * 2008-06-30 2013-09-11 日本光電工業株式会社 生体由来ガス成分分析装置及び疾病判定支援装置
JP5848608B2 (ja) * 2008-12-01 2016-01-27 トリコーンテク コーポレーションＴｒｉｃｏｒｎＴｅｃｈ Ｃｏｒｐｏｒａｔｉｏｎ 喘息、結核及び肺癌の診断及び疾患管理のための呼気分析システム及び方法
EA023922B1 (ru) 2009-09-09 2016-07-29 Сенса Буэс Аб Обнаружение лекарственного средства в выдыхаемом воздухе
US9417232B2 (en) 2009-10-02 2016-08-16 Bi Mobile Breath, Inc. Sobriety monitoring system
EP2591331A4 (en) * 2010-07-06 2017-06-07 Deton Corp. System for airborne bacterial sample collection and analysis
US8747325B2 (en) 2010-07-16 2014-06-10 Fundacao De Amparo A Pesquisa Do Estado De Sao Paulo (Fapesp) Non-invasive method for diagnosing the severity of heart failure by extracting and analyzing acetone concentrations in captured exhaled breath
US20120172677A1 (en) * 2010-12-30 2012-07-05 Logan Robert J Systems and methods for monitoring and processing biometric data
US11547322B2 (en) * 2012-02-08 2023-01-10 Lundin Stefan Device and method for non-invasive analysis of particles during medical ventilation
EP3667317A1 (en) 2012-03-08 2020-06-17 Sensa Bues AB A portable sampling device and method for detection of biomarkers in exhaled breath
US9164080B2 (en) * 2012-06-11 2015-10-20 Ohio State Innovation Foundation System and method for sensing NO
JP2016512431A (ja) * 2013-03-12 2016-04-28 デトン コーポレイション 呼吸サンプルの収集および分析のためのシステム
US10307080B2 (en) * 2014-03-07 2019-06-04 Spirosure, Inc. Respiratory monitor
ES2734380T3 (es) 2014-06-27 2019-12-05 Pulse Health Llc Cartucho de análisis y método de uso del mismo
KR20160009740A (ko) * 2014-07-16 2016-01-27 연세대학교 산학협력단 말디톱 질량분석기에 이용가능한 시료 플레이트 및 상기 시료 플레이트의 제조방법, 그리고 상기 시료 플레이트를 이용한 질량분석 방법
US10598668B2 (en) 2015-08-24 2020-03-24 Zeteo Tech, Inc. Coating of aerosol particles using an acoustic coater
EP3143930A1 (en) * 2015-09-21 2017-03-22 Université de Liège Method for the diagnosis of airway disease inflammatory subtype
US10226201B2 (en) * 2015-10-29 2019-03-12 Invoy Holdings, Llc Flow regulation device for breath analysis and related method
US11116422B2 (en) * 2015-12-21 2021-09-14 Koninklijke Philips N.V. Sample cells for respired gas sampling and methods of manufacturing same
KR20180137516A (ko) 2016-04-15 2018-12-27 예일 유니버시티 기체 환경에서 유기 화합물을 모니터링하기 위한 시스템, 기기 및 방법
US10502665B2 (en) * 2016-04-18 2019-12-10 University Of Maryland, College Park Aerosol collection system and method
CN109310368A (zh) 2016-04-25 2019-02-05 奥斯通医疗有限公司 用于捕获呼吸样本的系统和设备
US10960002B2 (en) * 2016-05-13 2021-03-30 The Brigham And Women's Hospital, Inc. Volatile metabolite profiles for the diagnosis and treatment of Mucorales fungi
AU2017353360B2 (en) * 2016-11-07 2023-01-19 AusMed Global Limited Non-invasive photonic sensing for monitoring diabetes
MX2020010523A (es) * 2017-02-27 2021-02-09 Third Pole Inc Sistemas y metodos para generar oxido nitrico.
GB201704367D0 (en) 2017-03-20 2017-05-03 Exhalation Tech Ltd A breath condensate analyser
JP6967198B2 (ja) 2017-05-18 2021-11-17 東海光学株式会社 呼気ミスト捕集装置、呼気ミスト分析システム、呼気ミスト捕集方法及び呼気ミスト分析方法
GB201801153D0 (en) * 2018-01-24 2018-03-07 Owlstone Med Ltd Apparatus and method for obtaining a breath sample
US20200147333A1 (en) * 2018-11-09 2020-05-14 Hound Labs, Inc. Breath sample systems for use with ventilators
US11678829B2 (en) 2019-04-17 2023-06-20 Masimo Corporation Physiological monitoring device attachment assembly
WO2021061247A2 (en) 2019-06-29 2021-04-01 Zeteo Tech, Inc. Methods and systems for detecting aerosol particles without using complex organic maldi matrices
CN117883121A (zh) 2019-08-26 2024-04-16 泽特奥科技公司 利用呼出气诊断结核病和其他疾病
CN114585903B (zh) 2019-09-23 2023-08-04 泽特奥科技公司 快速自主检测气溶胶粒子的系统和方法
KR102630689B1 (ko) 2020-04-03 2024-01-29 제테오 테크, 인코포레이티드 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단
US12364411B2 (en) * 2020-04-03 2025-07-22 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols
US20210318208A1 (en) 2020-04-09 2021-10-14 Hygieia Sciences LLC Method of Detection of Diseases Related to Coronavirus Infection by Breath Analysis
US12533047B2 (en) * 2020-04-19 2026-01-27 John J. Daniels Mask-based diagnostic system using exhaled breath condensate
US20240074673A1 (en) * 2021-03-31 2024-03-07 Zeteo Tech, Inc. Capturing truncated proteoforms in exhaled breath for diagnosis of tuberculosis
US20220386893A1 (en) * 2021-03-31 2022-12-08 Zeteo Tech Inc. Capturing truncated proteoforms in exhaled breath for diagnosis and treatment of diseases
EP4312749A4 (en) * 2021-03-31 2025-07-09 Zeteo Tech Inc DIAGNOSIS OF RESPIRATORY DISEASES BY CAPTURE OF AEROSOLIZED BIOMATERIAL PARTICLES USING FIXED BED SYSTEMS AND METHODS
SE546321C2 (en) 2021-04-08 2024-10-01 Pinsalus Ab System for breath analysis comprising a breath sampling apparatus and a sample preparation apparatus
WO2022251882A1 (en) 2021-05-28 2022-12-01 Entech Instruments Inc. System and method of gas sampling for trace-level analysis of chemical compounds

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001318069A (ja) 2000-05-10 2001-11-16 Matsushita Electric Ind Co Ltd 呼気ガス分析装置
JP2008501976A (ja) 2004-06-07 2008-01-24 ザ シャーロット‐メクレンバーグ ホスピタル オーソリティ 呼気凝縮液中のリポ多糖体を利用するグラム陰性菌性肺炎の診断
JP2018534955A (ja) 2015-09-15 2018-11-29 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 新生児医療を向上させる方法及び装置
WO2019011750A1 (en) 2017-07-10 2019-01-17 Pexa Ab NEW SYSTEM FOR COLLECTING EXPIRED PARTICLES
JP2020534511A (ja) 2017-07-10 2020-11-26 ペクサ アーベーＰｅｘａ Ａｂ 呼気粒子を捕集する新規システム

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