JP7395517B2 - ペプチド化合物およびその治療的用途 - Google Patents

ペプチド化合物およびその治療的用途 Download PDF

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Publication number
JP7395517B2
JP7395517B2 JP2020573032A JP2020573032A JP7395517B2 JP 7395517 B2 JP7395517 B2 JP 7395517B2 JP 2020573032 A JP2020573032 A JP 2020573032A JP 2020573032 A JP2020573032 A JP 2020573032A JP 7395517 B2 JP7395517 B2 JP 7395517B2
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peptide
seq
amino acid
peptides
proline
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Japanese (ja)
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JPWO2020012478A5 (https=
JP2021531246A5 (https=
JP2021531246A (ja
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エラン オヴァディア
アヴィ ベン－シモン
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Immunity Pharma Ltd
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Immunity Pharma Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
JP2020573032A 2018-07-11 2019-07-10 ペプチド化合物およびその治療的用途 Active JP7395517B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023201767A JP7682248B2 (ja) 2018-07-11 2023-11-29 ペプチド化合物およびその治療的用途

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL260555 2018-07-11
IL26055518 2018-07-11
PCT/IL2019/050774 WO2020012478A2 (en) 2018-07-11 2019-07-10 Peptide compounds and therapeutic uses of same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023201767A Division JP7682248B2 (ja) 2018-07-11 2023-11-29 ペプチド化合物およびその治療的用途

Publications (4)

Publication Number Publication Date
JP2021531246A JP2021531246A (ja) 2021-11-18
JPWO2020012478A5 JPWO2020012478A5 (https=) 2022-07-19
JP2021531246A5 JP2021531246A5 (https=) 2022-07-19
JP7395517B2 true JP7395517B2 (ja) 2023-12-11

Family

ID=69141375

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020573032A Active JP7395517B2 (ja) 2018-07-11 2019-07-10 ペプチド化合物およびその治療的用途
JP2023201767A Active JP7682248B2 (ja) 2018-07-11 2023-11-29 ペプチド化合物およびその治療的用途

Family Applications After (1)

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JP2023201767A Active JP7682248B2 (ja) 2018-07-11 2023-11-29 ペプチド化合物およびその治療的用途

Country Status (20)

Country Link
US (2) US11912790B2 (https=)
EP (2) EP3820882B1 (https=)
JP (2) JP7395517B2 (https=)
KR (1) KR102880543B1 (https=)
CN (1) CN112351989B (https=)
AU (2) AU2019300567B2 (https=)
BR (1) BR112020024748A2 (https=)
CA (1) CA3100961A1 (https=)
CO (1) CO2021001290A2 (https=)
EA (1) EA202190249A1 (https=)
ES (1) ES3026158T3 (https=)
HR (1) HRP20250746T1 (https=)
HU (1) HUE072141T2 (https=)
IL (2) IL317252A (https=)
MX (1) MX2021000264A (https=)
PL (1) PL3820882T3 (https=)
RS (1) RS66946B1 (https=)
SG (1) SG11202012773QA (https=)
WO (1) WO2020012478A2 (https=)
ZA (1) ZA202100587B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202012773QA (en) 2018-07-11 2021-01-28 Immunity Pharma Ltd Peptide compounds and therapeutic uses of same
IL272074B2 (en) * 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and methods of treating diseases using same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040204340A1 (en) 2003-04-11 2004-10-14 Guilford Pharmaceuticals, Inc. Polyprolyl inhibitors of cyclophilin
JP2008510796A (ja) 2004-08-23 2008-04-10 イエダ リサーチ アンド デベロップメント カンパニー リミテッド ストレス応答を媒介するためのペプチド阻害剤
US20160038571A1 (en) 2014-08-06 2016-02-11 Brown University Method and compositions for treatment of calcineurin-related diseases
JP2016516734A (ja) 2013-03-18 2016-06-09 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム オートファジー誘導ペプチド類似体

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
JPS4843906B1 (https=) * 1970-08-11 1973-12-21
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
WO1997044447A2 (en) * 1996-05-03 1997-11-27 President And Fellows Of Harvard College Transcriptional activation system, activators, and uses therefor
US6861256B2 (en) * 1997-05-15 2005-03-01 The General Hospital Corporation Therapeutic and diagnostic tools for impaired glucose tolerance conditions
GB9711148D0 (en) * 1997-05-31 1997-07-23 Peptide Therapeutics Ltd Human MAFA
EP0928968A1 (en) 1998-01-12 1999-07-14 Universität Basel Screening method for apoptosis and necrosis
EP1381839A4 (en) 2001-04-03 2005-10-12 Univ Leland Stanford Junior METHOD FOR THE IMAGE OF CELL DEOD IN VIVO
JP2008528630A (ja) * 2005-02-01 2008-07-31 アテニュオン，エルエルシー 抗血管新生ｐｈｓｃｎペプチドを含む組成物
US7704953B2 (en) * 2006-02-17 2010-04-27 Mdrna, Inc. Phage displayed cell binding peptides
JP2013505230A (ja) * 2009-09-17 2013-02-14 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド 酸化ストレス関連障害を処置するためのペプチド
WO2011126882A2 (en) * 2010-03-30 2011-10-13 American Type Culture Collection Therapeutic peptides and their derivatives and therapeutic uses thereof
US20130331297A1 (en) * 2010-07-16 2013-12-12 Avantgen, Inc. Novel peptides and uses thereof
BR112013015797B1 (pt) * 2010-12-23 2021-08-31 Shell Internationale Research Maatschappij B.V. Organismo microbiano e método de produzir um derivado de acil-coa graxo
EP2715350B1 (en) * 2011-05-23 2017-09-27 Yeda Research and Development Co. Ltd. Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same
US20140271666A1 (en) * 2013-03-14 2014-09-18 Immune Pharmaceuticals Ltd. Use of anti-eotaxin antibodies for treating inflammatory bowel disease
CN104045703B (zh) * 2013-03-15 2021-04-06 深圳君圣泰生物技术有限公司 一种多肽、多肽衍生物、多肽的可药用盐及药物组合物
ES2799404T3 (es) * 2014-07-15 2020-12-17 Yissum Research And Development Company Of The Hebrew Univ Of Jerusalem Ltd Polipéptidos de CD44 aislados y usos de los mismos
CA2988388C (en) 2015-04-23 2022-11-22 Nantomics, Llc Cancer neoepitopes
WO2017011338A1 (en) 2015-07-10 2017-01-19 President And Fellows Of Harvard College Sortase-mediated coupling of immunogenic polysaccharide-protein conjugates and their use
SG11202012773QA (en) 2018-07-11 2021-01-28 Immunity Pharma Ltd Peptide compounds and therapeutic uses of same
IL272074B2 (en) 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and methods of treating diseases using same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040204340A1 (en) 2003-04-11 2004-10-14 Guilford Pharmaceuticals, Inc. Polyprolyl inhibitors of cyclophilin
JP2008510796A (ja) 2004-08-23 2008-04-10 イエダ リサーチ アンド デベロップメント カンパニー リミテッド ストレス応答を媒介するためのペプチド阻害剤
JP2016516734A (ja) 2013-03-18 2016-06-09 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム オートファジー誘導ペプチド類似体
US20160038571A1 (en) 2014-08-06 2016-02-11 Brown University Method and compositions for treatment of calcineurin-related diseases

Also Published As

Publication number Publication date
AU2019300567B2 (en) 2024-09-19
KR20210045397A (ko) 2021-04-26
RS66946B1 (sr) 2025-07-31
US20240190919A1 (en) 2024-06-13
ZA202100587B (en) 2022-07-27
WO2020012478A3 (en) 2020-02-20
WO2020012478A2 (en) 2020-01-16
IL317252A (en) 2025-01-01
EA202190249A1 (ru) 2021-05-21
PL3820882T3 (pl) 2025-08-11
US20210261615A1 (en) 2021-08-26
JP2024026217A (ja) 2024-02-28
KR102880543B1 (ko) 2025-11-04
EP3820882B1 (en) 2025-04-02
EP4566617A3 (en) 2025-10-01
JP7682248B2 (ja) 2025-05-23
HUE072141T2 (hu) 2025-10-28
SG11202012773QA (en) 2021-01-28
MX2021000264A (es) 2021-05-12
IL280101B1 (en) 2025-01-01
AU2019300567A1 (en) 2021-02-25
JP2021531246A (ja) 2021-11-18
US11912790B2 (en) 2024-02-27
CN112351989B (zh) 2024-03-26
BR112020024748A2 (pt) 2021-03-23
ES3026158T3 (en) 2025-06-10
IL280101A (en) 2021-03-01
CN112351989A (zh) 2021-02-09
HRP20250746T1 (hr) 2025-08-15
CA3100961A1 (en) 2020-01-16
AU2024278477A1 (en) 2025-01-30
EP3820882A2 (en) 2021-05-19
IL280101B2 (en) 2025-05-01
CO2021001290A2 (es) 2021-02-26
EP4566617A2 (en) 2025-06-11
EP3820882C0 (en) 2025-04-02

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