JP7387179B2 - 発達障害の処置における（ｓ）－３－アミノ－４－（ジフルオロメチレニル）シクロペンタ－１－エン－１－カルボン酸および関連化合物、（１ｓ，３ｓ）－３－アミノ－４－（ジフルオロメチリデン）シクロペンタン－１－カルボン酸ならびにビガバトリンの使用 - Google Patents
発達障害の処置における（ｓ）－３－アミノ－４－（ジフルオロメチレニル）シクロペンタ－１－エン－１－カルボン酸および関連化合物、（１ｓ，３ｓ）－３－アミノ－４－（ジフルオロメチリデン）シクロペンタン－１－カルボン酸ならびにビガバトリンの使用 Download PDFInfo
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- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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| PCT/US2019/035934 WO2019236938A1 (en) | 2018-06-07 | 2019-06-07 | Use of (s)-3-amino-4-(difluoromethylenyl) cyclopent-1-ene-1-carboxylic acid and related compounds, (1s,3s)-3-amino-4-(difluoromethylidene) cyclopentane-1-carboxylic acid and vigabatrin in the treatment of developmental disorders |
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| JP2021527053A JP2021527053A (ja) | 2021-10-11 |
| JPWO2019236938A5 JPWO2019236938A5 (https=) | 2022-06-14 |
| JP2021527053A5 JP2021527053A5 (https=) | 2022-06-14 |
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| JP2020567857A Active JP7387179B2 (ja) | 2018-06-07 | 2019-06-07 | 発達障害の処置における（ｓ）－３－アミノ－４－（ジフルオロメチレニル）シクロペンタ－１－エン－１－カルボン酸および関連化合物、（１ｓ，３ｓ）－３－アミノ－４－（ジフルオロメチリデン）シクロペンタン－１－カルボン酸ならびにビガバトリンの使用 |
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| EP (1) | EP3813816B1 (https=) |
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| GB2591389A (en) | 2018-08-18 | 2021-07-28 | Ftf Pharma Private Ltd | Pharmaceuticals solution for oral dosage |
| WO2024058812A1 (en) | 2022-09-16 | 2024-03-21 | Pyros Pharmaceuticals, Inc. | Vigabatrin liquid pharmaceutical composition |
| AU2024220546A1 (en) * | 2023-02-17 | 2025-09-04 | Ovid Therapeutics Inc. | Use of (s)-3-amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic acid for gastrointestinal tract disorders and as an immunomodulatory agent |
| CN120641091A (zh) * | 2023-02-17 | 2025-09-12 | 奥维德医疗公司 | (s)-3-氨基-4-(二氟亚甲基)环戊-1-烯-1-甲酸在治疗糖尿病和前驱糖尿病中的用途 |
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| CA2790820A1 (en) | 2010-02-25 | 2011-09-01 | Northwestern University | Use (1s,3s)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid as a gaba aminotransferse inhibitor |
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| US10632088B2 (en) | 2016-10-10 | 2020-04-28 | Northwestern University | Inactivators of Toxoplasma gondii ornithine aminotransferase for treating toxoplasmosis and malaria |
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| IL279220B2 (en) | 2018-06-07 | 2023-12-01 | Ovid Therapeutics Inc | Use of (S)-3-amino-4-(difluoromethylenyl)cyclopentane-1-ene-1-carboxylic acid and related compounds, (1S, 3S)-3-amino-4-(difluoromethylidene)cyclopentane-1-carboxylic acid and vigabatrin In the treatment of developmental disorders |
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Non-Patent Citations (2)
| Title |
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| Genes，2016年，Vol.7，45 (page 1-13) |
| J. Am. Chem. Soc.，2018年01月，Vol.140，pp.2151-2164 |
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| CN112770739B (zh) | 2023-12-12 |
| IL304270A (en) | 2023-09-01 |
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| IL304270B2 (en) | 2024-10-01 |
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