JP7382646B2 - 移動する粒子の3次元撮像のためのシステム、デバイス、および方法 - Google Patents
移動する粒子の3次元撮像のためのシステム、デバイス、および方法 Download PDFInfo
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- JP7382646B2 JP7382646B2 JP2020543632A JP2020543632A JP7382646B2 JP 7382646 B2 JP7382646 B2 JP 7382646B2 JP 2020543632 A JP2020543632 A JP 2020543632A JP 2020543632 A JP2020543632 A JP 2020543632A JP 7382646 B2 JP7382646 B2 JP 7382646B2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1429—Signal processing
- G01N15/1433—Signal processing using image recognition
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
- G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
-
- H—ELECTRICITY
- H04—ELECTRIC COMMUNICATION TECHNIQUE
- H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
- H04N13/00—Stereoscopic video systems; Multi-view video systems; Details thereof
- H04N13/20—Image signal generators
- H04N13/204—Image signal generators using stereoscopic image cameras
- H04N13/254—Image signal generators using stereoscopic image cameras in combination with electromagnetic radiation sources for illuminating objects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1006—Investigating individual particles for cytology
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N2015/144—Imaging characterised by its optical setup
- G01N2015/1445—Three-dimensional imaging, imaging in different image planes, e.g. under different angles or at different depths, e.g. by a relative motion of sample and detector, for instance by tomography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
- G01N2015/1447—Spatial selection
- G01N2015/145—Spatial selection by pattern of light, e.g. fringe pattern
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- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Signal Processing (AREA)
- Electromagnetism (AREA)
- Multimedia (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862710576P | 2018-02-16 | 2018-02-16 | |
| US62/710,576 | 2018-02-16 | ||
| PCT/US2019/018631 WO2019161406A1 (en) | 2018-02-16 | 2019-02-19 | Systems, devices and methods for three-dimensional imaging of moving particles |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021514062A JP2021514062A (ja) | 2021-06-03 |
| JPWO2019161406A5 JPWO2019161406A5 (https=) | 2022-03-01 |
| JP2021514062A5 JP2021514062A5 (https=) | 2022-03-01 |
| JP7382646B2 true JP7382646B2 (ja) | 2023-11-17 |
Family
ID=67618955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020543632A Active JP7382646B2 (ja) | 2018-02-16 | 2019-02-19 | 移動する粒子の3次元撮像のためのシステム、デバイス、および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US11371929B2 (https=) |
| EP (1) | EP3752815B1 (https=) |
| JP (1) | JP7382646B2 (https=) |
| CN (1) | CN112041660B (https=) |
| WO (1) | WO2019161406A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3850080B1 (en) | 2018-09-14 | 2025-11-05 | The Regents of the University of California | Cell sorting device and method |
| WO2021041807A1 (en) * | 2019-08-30 | 2021-03-04 | The Regents Of The University Of California | Systems and methods for image cytometry |
| CN113092056A (zh) * | 2021-04-25 | 2021-07-09 | 中国空气动力研究与发展中心设备设计与测试技术研究所 | 一种高超声速流场三维密度场测量方法 |
| CN113959947A (zh) * | 2021-10-25 | 2022-01-21 | 山东大学 | 基于二维光散射的单颗粒多模态流式成像检测装置及方法 |
| TW202319805A (zh) * | 2021-11-12 | 2023-05-16 | 邑流微測股份有限公司 | 光學影像系統 |
| JP7770682B2 (ja) * | 2022-03-10 | 2025-11-17 | 国立大学法人 東京大学 | 3次元画像撮像装置 |
| DE102023101475A1 (de) * | 2023-01-20 | 2024-07-25 | Testo bioAnalytics GmbH | Verfahren und Messkanal zur optischen Aufzeichnung von Mikropartikeln in einem Partikelstrom |
| WO2024243036A1 (en) * | 2023-05-19 | 2024-11-28 | Nanocellect Biomedical, Inc. | Methods and systems for co-linear laser scanning |
| WO2025199233A1 (en) * | 2024-03-19 | 2025-09-25 | Cellularct | Method and apparatus for detection and analysis of suspended particles |
| US20250308080A1 (en) * | 2024-04-02 | 2025-10-02 | Becton, Dickinson And Company | Methods for label-free cell sorting and systems for same |
| WO2025236104A1 (en) * | 2024-05-17 | 2025-11-20 | Ecole Polytechnique De Montreal | System and method for 3d imaging flow cytometry |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020001089A1 (en) | 2000-04-18 | 2002-01-03 | Price Jeffrey H. | Multiparallel three dimensional optical microscopy system |
| JP2011512543A (ja) | 2008-02-18 | 2011-04-21 | ヴィジョンゲイト,インコーポレーテッド | 紫外放射を用いた生細胞の3次元画像化 |
| JP2012521540A (ja) | 2009-03-20 | 2012-09-13 | バイオ−ラド ラボラトリーズ インコーポレイテッド | 順次ライン走査符号化多色蛍光顕微鏡法および画像フローサイトメトリ |
| US20140071452A1 (en) | 2012-09-10 | 2014-03-13 | The Trustees Of Princeton University | Fluid channels for computational imaging in optofluidic microscopes |
| JP2014150412A (ja) | 2013-02-01 | 2014-08-21 | Hamamatsu Photonics Kk | 画像取得装置及び撮像装置 |
| US20160003729A1 (en) | 2009-03-10 | 2016-01-07 | The Regents Of The University Of California | Fluidic flow cytometry devices and particle sensing based on signal-encoding |
| CN106520535A (zh) | 2016-10-12 | 2017-03-22 | 山东大学 | 一种基于光片照明的免标记细胞检测装置及方法 |
| JP2017058352A (ja) | 2015-09-18 | 2017-03-23 | シスメックス株式会社 | 粒子撮像装置および粒子撮像方法 |
| WO2017214572A1 (en) | 2016-06-10 | 2017-12-14 | The Regents Of The University Of California | Image-based cell sorting systems and methods |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03146848A (ja) * | 1989-11-01 | 1991-06-21 | Canon Inc | アライメント機構を備える検体測定装置 |
| JP3838600B2 (ja) | 1998-01-07 | 2006-10-25 | 富士写真フイルム株式会社 | 画像形成方法及び画像形成装置 |
| US7023546B1 (en) * | 2003-10-21 | 2006-04-04 | The United States Of America As Represented By The Secretary Of The Army | Real-time imaging spectropolarimeter based on an optical modulator |
| EP1951437A2 (en) * | 2005-07-08 | 2008-08-06 | Wisconsin Alumni Research Foundation | Polyelectrolyte multilayer films at liquid-liquid interfaces and methods for providing and using same |
| US9013692B2 (en) * | 2008-06-12 | 2015-04-21 | East Carolina University | Flow cytometer apparatus for three dimensional difraction imaging and related methods |
| CN102869982B (zh) * | 2010-03-01 | 2014-04-30 | 奥林巴斯株式会社 | 光学分析装置、光学分析方法 |
| WO2016054293A1 (en) * | 2014-09-30 | 2016-04-07 | The Regents Of The University Of California | Imaging flow cytometer using spatial-temporal transformation |
| CN104502255B (zh) * | 2014-12-29 | 2017-04-05 | 中国科学院长春光学精密机械与物理研究所 | 三维成像流式细胞仪装置 |
| JP7130562B2 (ja) * | 2016-03-17 | 2022-09-05 | ベクトン・ディキンソン・アンド・カンパニー | ハイスループット蛍光フローサイトメーターを用いる細胞選別 |
| US10585028B2 (en) * | 2017-10-20 | 2020-03-10 | Charted Scientific, Inc. | Method and apparatus for optical analysis |
-
2019
- 2019-02-19 WO PCT/US2019/018631 patent/WO2019161406A1/en not_active Ceased
- 2019-02-19 US US16/970,304 patent/US11371929B2/en active Active
- 2019-02-19 JP JP2020543632A patent/JP7382646B2/ja active Active
- 2019-02-19 EP EP19753770.7A patent/EP3752815B1/en active Active
- 2019-02-19 CN CN201980026142.6A patent/CN112041660B/zh active Active
-
2022
- 2022-06-03 US US17/805,446 patent/US20220299421A1/en not_active Abandoned
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020001089A1 (en) | 2000-04-18 | 2002-01-03 | Price Jeffrey H. | Multiparallel three dimensional optical microscopy system |
| JP2011512543A (ja) | 2008-02-18 | 2011-04-21 | ヴィジョンゲイト,インコーポレーテッド | 紫外放射を用いた生細胞の3次元画像化 |
| US20160003729A1 (en) | 2009-03-10 | 2016-01-07 | The Regents Of The University Of California | Fluidic flow cytometry devices and particle sensing based on signal-encoding |
| JP2012521540A (ja) | 2009-03-20 | 2012-09-13 | バイオ−ラド ラボラトリーズ インコーポレイテッド | 順次ライン走査符号化多色蛍光顕微鏡法および画像フローサイトメトリ |
| US20140071452A1 (en) | 2012-09-10 | 2014-03-13 | The Trustees Of Princeton University | Fluid channels for computational imaging in optofluidic microscopes |
| JP2014150412A (ja) | 2013-02-01 | 2014-08-21 | Hamamatsu Photonics Kk | 画像取得装置及び撮像装置 |
| JP2017058352A (ja) | 2015-09-18 | 2017-03-23 | シスメックス株式会社 | 粒子撮像装置および粒子撮像方法 |
| WO2017214572A1 (en) | 2016-06-10 | 2017-12-14 | The Regents Of The University Of California | Image-based cell sorting systems and methods |
| CN106520535A (zh) | 2016-10-12 | 2017-03-22 | 山东大学 | 一种基于光片照明的免标记细胞检测装置及方法 |
Non-Patent Citations (1)
| Title |
|---|
| Emilio J. Gualda,Three-Dimensional Imaging Flow Cytometry Through Light-Sheet Fluorescence Microscopy,Cytometry,2017年,Part A, 91A,pp.144-151,DOI: 10.1002/cyto.a.23046 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019161406A1 (en) | 2019-08-22 |
| EP3752815B1 (en) | 2026-04-01 |
| US20210156788A1 (en) | 2021-05-27 |
| EP3752815A1 (en) | 2020-12-23 |
| US11371929B2 (en) | 2022-06-28 |
| CN112041660B (zh) | 2024-12-13 |
| EP3752815A4 (en) | 2021-11-03 |
| CN112041660A (zh) | 2020-12-04 |
| JP2021514062A (ja) | 2021-06-03 |
| US20220299421A1 (en) | 2022-09-22 |
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