CN112041660B - 用于移动粒子三维成像的系统、装置与方法 - Google Patents

用于移动粒子三维成像的系统、装置与方法 Download PDF

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Publication number
CN112041660B
CN112041660B CN201980026142.6A CN201980026142A CN112041660B CN 112041660 B CN112041660 B CN 112041660B CN 201980026142 A CN201980026142 A CN 201980026142A CN 112041660 B CN112041660 B CN 112041660B
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particle
light
particles
optical
plane
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CN112041660A (zh
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卢煜华
韩媛媛
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University of California San Diego UCSD
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University of California San Diego UCSD
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N13/00—Stereoscopic video systems; Multi-view video systems; Details thereof
    • H04N13/20—Image signal generators
    • H04N13/204—Image signal generators using stereoscopic image cameras
    • H04N13/254—Image signal generators using stereoscopic image cameras in combination with electromagnetic radiation sources for illuminating objects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/144—Imaging characterised by its optical setup
    • G01N2015/1445—Three-dimensional imaging, imaging in different image planes, e.g. under different angles or at different depths, e.g. by a relative motion of sample and detector, for instance by tomography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1447—Spatial selection
    • G01N2015/145—Spatial selection by pattern of light, e.g. fringe pattern

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Electromagnetism (AREA)
  • Multimedia (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201980026142.6A 2018-02-16 2019-02-19 用于移动粒子三维成像的系统、装置与方法 Active CN112041660B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862710576P 2018-02-16 2018-02-16
US62/710,576 2018-02-16
PCT/US2019/018631 WO2019161406A1 (en) 2018-02-16 2019-02-19 Systems, devices and methods for three-dimensional imaging of moving particles

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CN112041660A CN112041660A (zh) 2020-12-04
CN112041660B true CN112041660B (zh) 2024-12-13

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US (2) US11371929B2 (https=)
EP (1) EP3752815B1 (https=)
JP (1) JP7382646B2 (https=)
CN (1) CN112041660B (https=)
WO (1) WO2019161406A1 (https=)

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EP3850080B1 (en) 2018-09-14 2025-11-05 The Regents of the University of California Cell sorting device and method
WO2021041807A1 (en) * 2019-08-30 2021-03-04 The Regents Of The University Of California Systems and methods for image cytometry
CN113092056A (zh) * 2021-04-25 2021-07-09 中国空气动力研究与发展中心设备设计与测试技术研究所 一种高超声速流场三维密度场测量方法
CN113959947A (zh) * 2021-10-25 2022-01-21 山东大学 基于二维光散射的单颗粒多模态流式成像检测装置及方法
TW202319805A (zh) * 2021-11-12 2023-05-16 邑流微測股份有限公司 光學影像系統
JP7770682B2 (ja) * 2022-03-10 2025-11-17 国立大学法人 東京大学 ３次元画像撮像装置
DE102023101475A1 (de) * 2023-01-20 2024-07-25 Testo bioAnalytics GmbH Verfahren und Messkanal zur optischen Aufzeichnung von Mikropartikeln in einem Partikelstrom
WO2024243036A1 (en) * 2023-05-19 2024-11-28 Nanocellect Biomedical, Inc. Methods and systems for co-linear laser scanning
WO2025199233A1 (en) * 2024-03-19 2025-09-25 Cellularct Method and apparatus for detection and analysis of suspended particles
US20250308080A1 (en) * 2024-04-02 2025-10-02 Becton, Dickinson And Company Methods for label-free cell sorting and systems for same
WO2025236104A1 (en) * 2024-05-17 2025-11-20 Ecole Polytechnique De Montreal System and method for 3d imaging flow cytometry

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JP3838600B2 (ja) 1998-01-07 2006-10-25 富士写真フイルム株式会社 画像形成方法及び画像形成装置
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US7023546B1 (en) * 2003-10-21 2006-04-04 The United States Of America As Represented By The Secretary Of The Army Real-time imaging spectropolarimeter based on an optical modulator
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Also Published As

Publication number Publication date
WO2019161406A1 (en) 2019-08-22
EP3752815B1 (en) 2026-04-01
US20210156788A1 (en) 2021-05-27
EP3752815A1 (en) 2020-12-23
US11371929B2 (en) 2022-06-28
EP3752815A4 (en) 2021-11-03
CN112041660A (zh) 2020-12-04
JP2021514062A (ja) 2021-06-03
US20220299421A1 (en) 2022-09-22
JP7382646B2 (ja) 2023-11-17

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