JP7354161B2 - 向上した埋め込み後強度保持率を有する高強度縫合糸用の易吸収性コポリマー組成物 - Google Patents

向上した埋め込み後強度保持率を有する高強度縫合糸用の易吸収性コポリマー組成物 Download PDF

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JP7354161B2
JP7354161B2 JP2020573015A JP2020573015A JP7354161B2 JP 7354161 B2 JP7354161 B2 JP 7354161B2 JP 2020573015 A JP2020573015 A JP 2020573015A JP 2020573015 A JP2020573015 A JP 2020573015A JP 7354161 B2 JP7354161 B2 JP 7354161B2
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mole percent
glycolide
lactide
absorbable
polymerized
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JP2021529597A5 (https=
JP2021529597A (ja
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ジャミオルコフスキー・デニス・ディ
ディフェリス・クリストファー
アンジェリック・ササ
ケリー・ブライアン・エム
ウィスヌデル・マーク
スタイガー・ダニエル
チェン・カオユアン・ギャビン
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Ethicon Inc
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Ethicon Inc
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/06—Needles ; Sutures; Needle-suture combinations; Holders or packages for needles or suture materials
    • A61B17/06166—Sutures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A61L17/10—At least partially resorbable materials containing macromolecular materials
    • A61L17/12—Homopolymers or copolymers of glycolic acid or lactic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/06—At least partially resorbable materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/14—Post-treatment to improve physical properties
    • A61L17/145—Coating
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/64—Polyesters containing both carboxylic ester groups and carbonate groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C08G63/823—Preparation processes characterised by the catalyst used for the preparation of polylactones or polylactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C08G63/85—Germanium, tin, lead, arsenic, antimony, bismuth, titanium, zirconium, hafnium, vanadium, niobium, tantalum, or compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/106—Halogens or compounds thereof, e.g. iodine, chlorite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/442—Colorants, dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/452—Lubricants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Artificial Filaments (AREA)
JP2020573015A 2018-06-28 2019-06-19 向上した埋め込み後強度保持率を有する高強度縫合糸用の易吸収性コポリマー組成物 Active JP7354161B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/021,322 2018-06-28
US16/021,322 US11058792B2 (en) 2018-06-28 2018-06-28 Readily absorbable copolymer compositions for high strength sutures having enhanced strength retention post-implantation
PCT/IB2019/055179 WO2020003064A2 (en) 2018-06-28 2019-06-19 Readily absorbable copolymer compositions for high strength sutures having enhanced strength retention post-implantation

Publications (3)

Publication Number Publication Date
JP2021529597A JP2021529597A (ja) 2021-11-04
JP2021529597A5 JP2021529597A5 (https=) 2022-06-22
JP7354161B2 true JP7354161B2 (ja) 2023-10-02

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JP2020573015A Active JP7354161B2 (ja) 2018-06-28 2019-06-19 向上した埋め込み後強度保持率を有する高強度縫合糸用の易吸収性コポリマー組成物

Country Status (9)

Country Link
US (2) US11058792B2 (https=)
EP (1) EP3814098A4 (https=)
JP (1) JP7354161B2 (https=)
KR (1) KR102701355B1 (https=)
CN (1) CN112469550B (https=)
AU (1) AU2019293360B2 (https=)
BR (1) BR112020025759B1 (https=)
MX (1) MX2020013797A (https=)
WO (1) WO2020003064A2 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11136696B2 (en) * 2018-11-08 2021-10-05 Ethicon, Inc. Extrusion process for manufacturing of absorbable suture fibers

Citations (3)

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Publication number Priority date Publication date Assignee Title
US20040185250A1 (en) 2003-02-07 2004-09-23 John Amy T. Triclosan containing absorbable sutures with extended antimicrobial properties
JP2017504675A (ja) 2013-11-27 2017-02-09 エシコン・エルエルシーEthicon, LLC 高精度で制御可能な吸収速度を有する吸収性ポリマーブレンド組成物、加工方法、及び該組成物により提供される寸法的に安定な医療装置
JP2017505832A (ja) 2013-12-18 2017-02-23 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃ． 単官能性及び二官能性重合開始剤から調製されたコポリマーに基づく吸収性ポリマーブレンド組成物、加工方法、並びにそれらによる医療デバイス

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US3836297A (en) * 1970-11-05 1974-09-17 Armstrong Cork Co Marbleizing apparatus
US3839297A (en) 1971-11-22 1974-10-01 Ethicon Inc Use of stannous octoate catalyst in the manufacture of l(-)lactide-glycolide copolymer sutures
US4243775A (en) 1978-11-13 1981-01-06 American Cyanamid Company Synthetic polyester surgical articles
US5007923A (en) * 1990-01-31 1991-04-16 Ethicon, Inc. Crystalline copolyesters of amorphous (lactide/glycolide) and p-dioxanone
US5133739A (en) 1990-02-06 1992-07-28 Ethicon, Inc. Segmented copolymers of ε-caprolactone and glycolide
US5236444A (en) 1992-10-27 1993-08-17 United States Surgical Corporation Absorbable polymers and surgical articles made therefrom
DE19641335A1 (de) 1996-10-08 1998-04-09 Inst Textil & Faserforschung Triblockterpolymer, seine Verwendung für chirurgisches Nahtmaterial und Verfahren zur Herstellung
US6007565A (en) * 1997-09-05 1999-12-28 United States Surgical Absorbable block copolymers and surgical articles fabricated therefrom
DE69834375T2 (de) 1997-10-10 2007-03-15 Ethicon, Inc. Geflochtenes Nahtmaterial mit verbesserter Knotenfestigkeit
US6183499B1 (en) * 1998-09-11 2001-02-06 Ethicon, Inc. Surgical filament construction
US6848152B2 (en) 2001-08-31 2005-02-01 Quill Medical, Inc. Method of forming barbs on a suture and apparatus for performing same
KR100453130B1 (ko) 2001-11-21 2004-10-15 한국과학기술연구원 구조적 배열이 일정한 생분해성 락타이드(글리콜라이드또는 락타이드/글리콜라이드)/ε-카프로락톤 멀티블록공중합체 및 이의 제조 방법
US6476180B1 (en) 2001-11-30 2002-11-05 E. I. Du Pont De Nemours And Company Process for producing an oriented shaped article
US6831149B2 (en) 2002-06-28 2004-12-14 Ethicon, Inc. Polymerization process using mono-and di-functional initiators to prepare fast crystallizing polylactone copolymers
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Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040185250A1 (en) 2003-02-07 2004-09-23 John Amy T. Triclosan containing absorbable sutures with extended antimicrobial properties
JP2017504675A (ja) 2013-11-27 2017-02-09 エシコン・エルエルシーEthicon, LLC 高精度で制御可能な吸収速度を有する吸収性ポリマーブレンド組成物、加工方法、及び該組成物により提供される寸法的に安定な医療装置
JP2017505832A (ja) 2013-12-18 2017-02-23 エシコン・インコーポレイテッドＥｔｈｉｃｏｎ， Ｉｎｃ． 単官能性及び二官能性重合開始剤から調製されたコポリマーに基づく吸収性ポリマーブレンド組成物、加工方法、並びにそれらによる医療デバイス

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Title
International Journal of Polymeric Materials and Polymeric Biomaterials，2016年，Vol.65, No.6，pp.277-284，http://dx.doi.org/10.1080/00914037.2015.1119683

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Publication number Publication date
AU2019293360B2 (en) 2024-06-20
WO2020003064A2 (en) 2020-01-02
MX2020013797A (es) 2021-05-27
BR112020025759B1 (pt) 2024-03-05
EP3814098A2 (en) 2021-05-05
AU2019293360A1 (en) 2020-12-17
KR20210024626A (ko) 2021-03-05
CN112469550A (zh) 2021-03-09
US20210322624A1 (en) 2021-10-21
KR102701355B1 (ko) 2024-09-05
BR112020025759A2 (pt) 2021-03-16
EP3814098A4 (en) 2022-03-16
US20200000958A1 (en) 2020-01-02
JP2021529597A (ja) 2021-11-04
US11058792B2 (en) 2021-07-13
CN112469550B (zh) 2023-01-31
WO2020003064A3 (en) 2020-06-04
US11596709B2 (en) 2023-03-07

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