JP7336455B2 - 用量カウント機構を有する薬剤送達装置 - Google Patents
用量カウント機構を有する薬剤送達装置 Download PDFInfo
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
- A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31526—Dosing by means of stepwise axial movements, e.g. ratchet mechanisms or detents
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
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- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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- A61M2005/2006—Having specific accessories
- A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2093—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically including concentration setting means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
- A61M2005/3126—Specific display means related to dosing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31568—Means keeping track of the total dose administered, e.g. since the cartridge was inserted
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
Claims (8)
- 所定の回数の用量排出動作を行う薬剤送達装置(10)であって、前記薬剤送達装置(10)が、
-軸に沿って延在し、用量排出機構を収容するハウジング(11)と、
-前記用量排出機構と動作可能に連結され、かつ各用量排出動作の間に、前記ハウジング(11)に対する既定の運動を受けて、用量を排出することを可能にするように構成された往復要素(14)であって、前記既定の運動が、第1の位置から第2の位置への第1の軸方向の変位、続いて前記第2の位置から前記第1の位置への第2の軸方向の変位を含む、往復要素(14)と、
-前記ハウジング(11)に対して前記第1の軸方向に移動可能なカウンター要素(16)と、
-前記第1の軸方向の運動を阻止し、かつ前記カウンター要素(16)に対する前記往復要素(14)の前記第2の軸方向の運動を可能にするように構成された第1の一方向性ラチェット機構と、
-前記第1の軸方向の運動を可能にし、かつ前記ハウジング(11)に対する前記カウンター要素(16)の前記第2の軸方向の運動を阻止するように構成された第2の一方向性ラチェット機構と、を備える、薬剤送達装置(10)。 - 前記ハウジング(11)に対して軸方向および回転方向に固定された基部部材(15)をさらに備え、前記第1の一方向性ラチェット機構が、前記往復要素(14)および前記カウンター要素(16)のうちの一方の上にある第1の軸方向の待歯(14t)と、前記往復要素(14)および前記カウンター要素(16)のうちのもう一方の上にある歯止め部材(16h)と、を備え、前記第2の一方向性ラチェット機構が、前記カウンター要素(16)および前記基部部材(15)のうちの一方の上にある第2の軸方向の待歯(15t)と、前記カウンター要素(16)および前記基部部材(15)のうちのもう一方の上にある歯止め部材(16f)と、を含む、請求項1に記載の薬剤送達装置。
- 前記カウンター要素(16)が、前記所定の回数の用量排出動作に対応するいくつかの工程の中で、使用前位置から内容量終了位置まで前記ハウジング(11)に対する前記第1の軸方向の運動を受け、かつ前記内容量終了位置に到達することに応答して、前記基部部材(15)との軸方向の相互係止係合に入り、それによって、前記ハウジング(11)に対する前記第1の軸方向のさらなる運動を阻止するように構成されている、請求項1または2に記載の薬剤送達装置。
- 前記ハウジング(11)の軸方向延在部に配置された薬剤貯蔵部ホルダー(30)をさらに備え、前記用量排出機構が、前記往復要素(14)を付勢力に対して前記第1の軸方向に変位させるように、前記薬剤貯蔵部ホルダー(30)の遠位端部分から動作可能な起動構造(7、12、13)を備える、請求項1~3のいずれか一項に記載の薬剤送達装置。
- 前記薬剤貯蔵部ホルダー(30)が、前記遠位端部分で針モジュール(40)を受容し、かつ前記針モジュール(40)の軸方向に移動可能な部分と前記起動構造(7、12、13)との動作可能な連結を提供するように構成された受容手段(31、32)を備える、請求項4に記載の薬剤送達装置。
- 前記針モジュール(40)の前記軸方向に移動可能な部分が、皮膚挿入可能な前方針(43)を選択的に被覆したり、露出させるように適合された針シールド(45)であり、受容した針モジュール(40)の前記針シールド(45)が、前記皮膚挿入可能な前方針(43)の露出に応答して、前記往復要素(14)を前記第1の軸方向に変位させるように構成されている、請求項5に記載の薬剤送達装置。
- 前記ハウジング(11)に対する装填部材(20)の遠位の運動に応答して、前記薬剤送達装置から送達される用量を調製するように構成された用量調製構造(5、13、15、17、20)と、前記薬剤貯蔵部ホルダー(30)のための保護キャップ(60)と、をさらに備え、前記保護キャップ(60)が、前記薬剤貯蔵部ホルダー(30)を被覆しているときに、前記用量調製構造(5、13、15、17、20)と動作可能に連結され、かつカートリッジホルダー(30)から取り外されることに応答して、前記ハウジング(11)に対して遠位に前記装填部材(20)を移動させるように構成されている、請求項4~6のいずれか一項に記載の薬剤送達装置。
- 前記用量排出機構が、ねじりばね部材(5)によって動力供給され、前記用量調製構造(5、13、15、17、20)が、前記ねじりばね部材(5)を緊張させるためのばね緊張機構を備え、かつ前記ハウジング(11)に対する前記装填部材(20)の遠位の運動を、前記ハウジング(11)に対するばね緊張部材(17)の回転に変換するように構成されており、前記カウンター要素(16)が、前記ハウジング(11)に対して回転方向に固定され、かつ前記内容量終了位置に到達することに応答して、前記ばね緊張部材(17)との回転方向の相互係止係合に入り、それによって、前記ハウジング(11)に対する前記装填部材(20)の遠位の運動を阻止するように構成されている、請求項7に記載の薬剤送達装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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EP18163689.5 | 2018-03-23 | ||
EP18163689 | 2018-03-23 | ||
PCT/EP2019/057261 WO2019180214A1 (en) | 2018-03-23 | 2019-03-22 | Drug delivery device with dose counting mechanism |
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JP2021518195A JP2021518195A (ja) | 2021-08-02 |
JP7336455B2 true JP7336455B2 (ja) | 2023-08-31 |
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US (1) | US20210023310A1 (ja) |
EP (1) | EP3768355A1 (ja) |
JP (1) | JP7336455B2 (ja) |
CN (1) | CN111936184A (ja) |
WO (1) | WO2019180214A1 (ja) |
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US11554226B2 (en) | 2019-05-17 | 2023-01-17 | Norton (Waterford) Limited | Drug delivery device with electronics |
WO2021007154A1 (en) | 2019-07-05 | 2021-01-14 | Norton (Waterford) Limited | Drug delivery device with electronics and power management |
JP2024510093A (ja) * | 2021-02-18 | 2024-03-06 | ノボ・ノルデイスク・エー/エス | 所定の固定用量を送達するための薬剤送達装置 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005514120A (ja) | 2002-01-10 | 2005-05-19 | オウエン マンフォード リミティド | 医療用注射装置に関する改良 |
JP2015511847A (ja) | 2012-03-02 | 2015-04-23 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 固定用量薬剤送達デバイス |
JP2015521511A (ja) | 2012-06-29 | 2015-07-30 | ノボ・ノルデイスク・エー/エス | ばね駆動注射装置のためのシールドロック |
WO2016201586A1 (en) | 2015-06-17 | 2016-12-22 | Techpharma Licensing Ag | Dose setting and dose limiting mechanism for an injection device and method for programming the dose limitation |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW453884B (en) | 1999-09-16 | 2001-09-11 | Novo Nordisk As | Dose setting limiter |
US6899699B2 (en) * | 2001-01-05 | 2005-05-31 | Novo Nordisk A/S | Automatic injection device with reset feature |
MX2015012901A (es) * | 2013-03-14 | 2016-04-04 | Norton Healthcare Ltd | Mecanismo de dispensacion para un dispositivo medico. |
JP6366680B2 (ja) * | 2013-04-10 | 2018-08-01 | サノフイ | 薬物送達デバイスの駆動機構 |
JP6397490B2 (ja) * | 2013-06-14 | 2018-09-26 | ノボ・ノルデイスク・エー/エス | 2層ばねを有する薬剤送出装置 |
CN105517605A (zh) * | 2013-09-16 | 2016-04-20 | 诺和诺德股份有限公司 | 用于选择性的按固定剂量给药或按可变剂量给药的注射设备 |
US20160317751A1 (en) * | 2013-12-20 | 2016-11-03 | Novo Nordisk A/S | Mechanical Dose Expelled Indicator |
JP6622223B2 (ja) * | 2014-05-28 | 2019-12-18 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 薬物送達デバイス用の用量設定機構、および薬物送達デバイス |
JP2017535360A (ja) * | 2014-11-24 | 2017-11-30 | サノフイ | 可変用量薬物送達デバイスに薬剤の最大用量を設定するための機構 |
US10688246B2 (en) * | 2014-12-10 | 2020-06-23 | Sanofi | Space saving drug injection device |
JP6644793B2 (ja) * | 2014-12-22 | 2020-02-12 | ノボ・ノルデイスク・エー/エス | ばね駆動式薬剤送達装置 |
US20170340836A1 (en) * | 2014-12-29 | 2017-11-30 | Novo Nordisk A/S | A Multi-State Ratchet Mechanism for Drug Injection Devices |
US20170296753A1 (en) * | 2016-04-18 | 2017-10-19 | Accunit, Llc | Handheld medical substance dispensing system, apparatus and methods |
EP3576819B1 (en) * | 2017-02-03 | 2023-08-16 | Norton Healthcare Limited | Assembly for a medication delivery device and medication delivery device |
CA3069818A1 (en) * | 2017-07-21 | 2019-01-24 | Becton Dickinson France | Assisted injection device for injecting a composition contained in a medical container |
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2019
- 2019-03-22 EP EP19711386.3A patent/EP3768355A1/en active Pending
- 2019-03-22 WO PCT/EP2019/057261 patent/WO2019180214A1/en active Application Filing
- 2019-03-22 CN CN201980021577.1A patent/CN111936184A/zh active Pending
- 2019-03-22 US US16/981,328 patent/US20210023310A1/en active Pending
- 2019-03-22 JP JP2020550069A patent/JP7336455B2/ja active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005514120A (ja) | 2002-01-10 | 2005-05-19 | オウエン マンフォード リミティド | 医療用注射装置に関する改良 |
JP2015511847A (ja) | 2012-03-02 | 2015-04-23 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 固定用量薬剤送達デバイス |
JP2015521511A (ja) | 2012-06-29 | 2015-07-30 | ノボ・ノルデイスク・エー/エス | ばね駆動注射装置のためのシールドロック |
WO2016201586A1 (en) | 2015-06-17 | 2016-12-22 | Techpharma Licensing Ag | Dose setting and dose limiting mechanism for an injection device and method for programming the dose limitation |
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CN111936184A (zh) | 2020-11-13 |
JP2021518195A (ja) | 2021-08-02 |
WO2019180214A1 (en) | 2019-09-26 |
EP3768355A1 (en) | 2021-01-27 |
US20210023310A1 (en) | 2021-01-28 |
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