JP7291217B2 - 足場非依存性細胞およびその使用 - Google Patents

足場非依存性細胞およびその使用 Download PDF

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JP7291217B2
JP7291217B2 JP2021525327A JP2021525327A JP7291217B2 JP 7291217 B2 JP7291217 B2 JP 7291217B2 JP 2021525327 A JP2021525327 A JP 2021525327A JP 2021525327 A JP2021525327 A JP 2021525327A JP 7291217 B2 JP7291217 B2 JP 7291217B2
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cells
anchorage
connective tissue
independent
cell
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JP2022509054A (ja
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ナーミアス，ヤーコブ
コヘン，メラブ
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イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム・リミテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0656—Adult fibroblasts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L13/00—Meat products; Meat meal; Preparation or treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • C12N2509/10—Mechanical dissociation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2021525327A 2018-11-08 2019-11-07 足場非依存性細胞およびその使用 Active JP7291217B2 (ja)

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JP2023014671A JP2023055867A (ja) 2018-11-08 2023-02-02 足場非依存性細胞およびその使用

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US201862757275P 2018-11-08 2018-11-08
US62/757,275 2018-11-08
PCT/IL2019/051219 WO2020095305A1 (en) 2018-11-08 2019-11-07 Anchorage-independent cells and use thereof

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JP2022509054A JP2022509054A (ja) 2022-01-20
JP2022509054A5 JP2022509054A5 (https=) 2022-02-09
JP7291217B2 true JP7291217B2 (ja) 2023-06-14

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US (1) US20210395690A1 (https=)
EP (1) EP3877508A1 (https=)
JP (2) JP7291217B2 (https=)
KR (4) KR102871263B1 (https=)
CN (1) CN113227356A (https=)
AU (1) AU2019377278C9 (https=)
IL (3) IL298567B2 (https=)
WO (1) WO2020095305A1 (https=)

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US20220195392A1 (en) * 2019-04-23 2022-06-23 The Regents Of The University Of California Methods and compositions for cell culture on heterogeneous scaffolds
WO2021148960A1 (en) * 2020-01-21 2021-07-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Utilization of fgf activators in culture media
JP2023539149A (ja) * 2020-08-21 2023-09-13 メルク パテント ゲーエムベーハー 食用中空繊維において増殖した筋肉細胞を用いて生成された可食組織様構造
JP2022072917A (ja) * 2020-10-30 2022-05-17 株式会社ダイセル 培養食肉複合体、及びその製造方法
AU2022222783A1 (en) * 2021-02-22 2023-09-07 Vitrolabs Inc Immortalized cell line for engineered synthetic leather
US20240191198A1 (en) * 2021-04-13 2024-06-13 Bluenalu, Inc. Cell-cultured food products and related cells, compositions, methods and systems
AU2022369299A1 (en) 2021-10-19 2024-03-14 Eat Scifi Inc. Plant base/animal cell hybrid meat substitute
WO2024048588A1 (ja) * 2022-08-31 2024-03-07 インテグリカルチャー株式会社 細胞培養システム、培養肉、及び培養上清

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JP2006246715A (ja) 2005-03-08 2006-09-21 Osaka Bioscience Institute 足場非依存的増殖能を指標とした癌遺伝子及びその機能阻害物質の探索方法
JP2017536853A (ja) 2014-12-04 2017-12-14 カソリック・クァンドン・ユニヴァーシティ・テクノロジー・ホールディングス・カンパニー・リミテッド エネルギーを利用した多能性細胞誘導装置及び方法
WO2018011805A2 (en) 2016-07-11 2018-01-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Systems and methods for growing cells in vitro

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JP2017536853A (ja) 2014-12-04 2017-12-14 カソリック・クァンドン・ユニヴァーシティ・テクノロジー・ホールディングス・カンパニー・リミテッド エネルギーを利用した多能性細胞誘導装置及び方法
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KR20240004541A (ko) 2024-01-11
KR20230091997A (ko) 2023-06-23
AU2019377278C9 (en) 2025-08-14
IL298567A (en) 2023-01-01
IL282976B1 (en) 2023-01-01
EP3877508A1 (en) 2021-09-15
JP2022509054A (ja) 2022-01-20
IL298567B1 (en) 2023-06-01
KR102605256B1 (ko) 2023-11-24
KR20210091226A (ko) 2021-07-21
AU2019377278A1 (en) 2021-06-03
KR102871263B1 (ko) 2025-10-16
IL298567B2 (en) 2023-10-01
WO2020095305A1 (en) 2020-05-14
IL302532A (en) 2023-07-01
AU2019377278C1 (en) 2025-07-24
IL282976B2 (en) 2023-05-01
IL282976A (en) 2021-06-30
JP2023055867A (ja) 2023-04-18
KR20250162599A (ko) 2025-11-18
CN113227356A (zh) 2021-08-06
US20210395690A1 (en) 2021-12-23
BR112021008808A2 (pt) 2021-09-08
AU2019377278B2 (en) 2022-11-17

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