JP7290288B2 - 免疫不全及び自己免疫疾患を治療するための、造血幹細胞でｆｏｘｐ３を発現するレンチウイルスベクター - Google Patents

免疫不全及び自己免疫疾患を治療するための、造血幹細胞でｆｏｘｐ３を発現するレンチウイルスベクター Download PDF

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JP7290288B2
JP7290288B2 JP2020511428A JP2020511428A JP7290288B2 JP 7290288 B2 JP7290288 B2 JP 7290288B2 JP 2020511428 A JP2020511428 A JP 2020511428A JP 2020511428 A JP2020511428 A JP 2020511428A JP 7290288 B2 JP7290288 B2 JP 7290288B2
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foxp3
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expression
panel
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ドナルド・ビー・コーン
マリア・グラツィア・ロンカローロ
ロジャー・ピー・ホリス
ケイトリン・イー・マシウク
ローザ・バチェッタ
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University of California, San Diego
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JP2020511428A 2017-08-22 2018-08-22 免疫不全及び自己免疫疾患を治療するための、造血幹細胞でｆｏｘｐ３を発現するレンチウイルスベクター Active JP7290288B2 (ja)

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US201762548891P 2017-08-22 2017-08-22
US62/548,891 2017-08-22
PCT/US2018/047586 WO2019040655A1 (en) 2017-08-22 2018-08-22 LENTIVIRAL VECTORS EXPRESSING FOXP3 IN HEMATOPOIETIC STEM CELLS TO TREAT IMMUNITY DEFICIENCIES AND AUTOIMMUNE DISEASES

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JP2020533969A JP2020533969A (ja) 2020-11-26
JP2020533969A5 JP2020533969A5 (enExample) 2021-09-30
JP7290288B2 true JP7290288B2 (ja) 2023-06-13

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US (2) US12060566B2 (enExample)
EP (1) EP3672617A4 (enExample)
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Families Citing this family (12)

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Publication number Priority date Publication date Assignee Title
CA3042179A1 (en) 2016-10-31 2018-05-03 Seattle Children's Hospital (dba Seattle Children's Research Institute) Method for treating autoimmune disease using cd4 t-cells with engineered stabilization of expression of endogenous foxp3 gene
WO2019040655A1 (en) * 2017-08-22 2019-02-28 The Regents Of The University Of California LENTIVIRAL VECTORS EXPRESSING FOXP3 IN HEMATOPOIETIC STEM CELLS TO TREAT IMMUNITY DEFICIENCIES AND AUTOIMMUNE DISEASES
JP7575949B2 (ja) * 2018-04-27 2024-10-31 シアトル チルドレンズ ホスピタル ディー／ビー／エイ シアトル チルドレンズ リサーチ インスティテュート 遺伝子編集ｔ細胞におけるヒトｆｏｘｐ３の発現
SG11202007878UA (en) 2018-04-27 2020-09-29 Seattle Childrens Hospital Dba Seattle Childrens Res Inst Expression of foxp3 in edited cd34+ cells
WO2020216807A1 (en) * 2019-04-23 2020-10-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of inducing or restoring immune tolerance
EP3980035A4 (en) * 2019-06-07 2023-08-23 The Board Of Trustees Of The Leland Stanford Junior University GENETICALLY MODIFIED CD4+ T LYMPHOCYTES FOR USE IN TREG-BASED IMMUNOTHERAPY
WO2021028359A1 (en) * 2019-08-09 2021-02-18 Sangamo Therapeutics France Controlled expression of chimeric antigen receptors in t cells
EP4410965A4 (en) * 2021-09-27 2025-09-24 Univ Kyoto T LYMPHOCYTE PRODUCTION PROCESS
JPWO2023149555A1 (enExample) * 2022-02-04 2023-08-10
EP4497822A4 (en) * 2022-03-23 2026-03-18 Univ Kyoto PROCESS FOR THE PRODUCTION OF REGULATORY T LYMPHOCYTES
CN120112629A (zh) * 2022-09-26 2025-06-06 国立大学法人京都大学 T细胞产生方法
CN122382014A (zh) * 2026-06-17 2026-07-14 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 抗鸡Foxp3单克隆抗体、分泌该单克隆抗体的杂交瘤细胞株及其应用

Citations (1)

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JP2004208548A (ja) 2002-12-27 2004-07-29 Institute Of Physical & Chemical Research 免疫反応の抗原特異的抑制

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US7507542B2 (en) 2001-05-08 2009-03-24 Ucb Sa Method for regulating immune function using the FOXP3 protein
US8158596B2 (en) * 2007-05-11 2012-04-17 The Regents Of The University Of Michigan Materials and methods for FOXP3 tumor suppression
US20140065110A1 (en) 2012-08-31 2014-03-06 The Regents Of The University Of California Genetically modified msc and therapeutic methods
US9663564B2 (en) 2013-03-15 2017-05-30 The Regents Of The University Of California Vectors and methods to treat ischemia
WO2014121840A1 (en) * 2013-02-07 2014-08-14 Medizinische Hochschule Hannover Induced dendritic cells and uses thereof
GB201318347D0 (en) * 2013-10-16 2013-11-27 Ucl Business Plc Retroviral vectors
US11911415B2 (en) 2015-06-09 2024-02-27 Editas Medicine, Inc. CRISPR/Cas-related methods and compositions for improving transplantation
WO2019040655A1 (en) 2017-08-22 2019-02-28 The Regents Of The University Of California LENTIVIRAL VECTORS EXPRESSING FOXP3 IN HEMATOPOIETIC STEM CELLS TO TREAT IMMUNITY DEFICIENCIES AND AUTOIMMUNE DISEASES

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
JP2004208548A (ja) 2002-12-27 2004-07-29 Institute Of Physical & Chemical Research 免疫反応の抗原特異的抑制

Non-Patent Citations (3)

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J. Exp. Med.，2007年，Vol. 204, No. 7，pp.1543-1551
Nat. Immunol.，2008年，Vol. 9, No. 2，pp.194-202
Nature，2010年，Vol. 463，pp.808-812

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US20200347404A1 (en) 2020-11-05
JP2020533969A (ja) 2020-11-26
US20240336935A1 (en) 2024-10-10
WO2019040655A1 (en) 2019-02-28
KR20200054210A (ko) 2020-05-19
EP3672617A4 (en) 2021-06-23
US12060566B2 (en) 2024-08-13
KR102780121B1 (ko) 2025-03-12
EP3672617A1 (en) 2020-07-01

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