JP7282793B2 - ゼロ・デッドボリューム・フィッティングアッセンブリー - Google Patents
ゼロ・デッドボリューム・フィッティングアッセンブリー Download PDFInfo
- Publication number
- JP7282793B2 JP7282793B2 JP2020544855A JP2020544855A JP7282793B2 JP 7282793 B2 JP7282793 B2 JP 7282793B2 JP 2020544855 A JP2020544855 A JP 2020544855A JP 2020544855 A JP2020544855 A JP 2020544855A JP 7282793 B2 JP7282793 B2 JP 7282793B2
- Authority
- JP
- Japan
- Prior art keywords
- primary seal
- ferrule
- dead volume
- zero dead
- volume fitting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000013011 mating Effects 0.000 claims description 4
- 230000000717 retained effect Effects 0.000 claims 1
- 239000011347 resin Substances 0.000 description 5
- 229920005989 resin Polymers 0.000 description 5
- 230000006835 compression Effects 0.000 description 4
- 238000007906 compression Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 239000004696 Poly ether ether ketone Substances 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 229920000840 ethylene tetrafluoroethylene copolymer Polymers 0.000 description 2
- 229920002530 polyetherether ketone Polymers 0.000 description 2
- -1 polytetrafluoroethylene Polymers 0.000 description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000004812 Fluorinated ethylene propylene Substances 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- JUPQTSLXMOCDHR-UHFFFAOYSA-N benzene-1,4-diol;bis(4-fluorophenyl)methanone Chemical compound OC1=CC=C(O)C=C1.C1=CC(F)=CC=C1C(=O)C1=CC=C(F)C=C1 JUPQTSLXMOCDHR-UHFFFAOYSA-N 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 description 1
- 239000005350 fused silica glass Substances 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229920009441 perflouroethylene propylene Polymers 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- BFKJFAAPBSQJPD-UHFFFAOYSA-N tetrafluoroethene Chemical group FC(F)=C(F)F BFKJFAAPBSQJPD-UHFFFAOYSA-N 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Images
Classifications
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L19/00—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts
- F16L19/02—Pipe ends provided with collars or flanges, integral with the pipe or not, pressed together by a screwed member
- F16L19/0212—Pipe ends provided with collars or flanges, integral with the pipe or not, pressed together by a screwed member using specially adapted sealing means
- F16L19/0218—Pipe ends provided with collars or flanges, integral with the pipe or not, pressed together by a screwed member using specially adapted sealing means comprising only sealing rings
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L19/00—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts
- F16L19/02—Pipe ends provided with collars or flanges, integral with the pipe or not, pressed together by a screwed member
- F16L19/0231—Pipe ends provided with collars or flanges, integral with the pipe or not, pressed together by a screwed member with specially adapted means for positioning the threaded member behind the collar
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L19/00—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts
- F16L19/06—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts in which radial clamping is obtained by wedging action on non-deformed pipe ends
- F16L19/065—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts in which radial clamping is obtained by wedging action on non-deformed pipe ends the wedging action being effected by means of a ring
- F16L19/0653—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts in which radial clamping is obtained by wedging action on non-deformed pipe ends the wedging action being effected by means of a ring the ring being rotatably connected to one of the connecting parts
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L19/00—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts
- F16L19/06—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts in which radial clamping is obtained by wedging action on non-deformed pipe ends
- F16L19/07—Joints in which sealing surfaces are pressed together by means of a member, e.g. a swivel nut, screwed on, or into, one of the joint parts in which radial clamping is obtained by wedging action on non-deformed pipe ends adapted for use in socket or sleeve connections
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6004—Construction of the column end pieces
- G01N30/6026—Fluid seals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
- G01N30/6034—Construction of the column joining multiple columns
- G01N30/6039—Construction of the column joining multiple columns in series
Landscapes
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Gasket Seals (AREA)
- Joints With Pressure Members (AREA)
- Valve Housings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862635196P | 2018-02-26 | 2018-02-26 | |
| US62/635,196 | 2018-02-26 | ||
| PCT/US2019/019544 WO2019165415A1 (en) | 2018-02-26 | 2019-02-26 | Zero dead volume fitting assembly |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021515152A JP2021515152A (ja) | 2021-06-17 |
| JP2021515152A5 JP2021515152A5 (enExample) | 2021-09-09 |
| JP7282793B2 true JP7282793B2 (ja) | 2023-05-29 |
Family
ID=67685698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544855A Active JP7282793B2 (ja) | 2018-02-26 | 2019-02-26 | ゼロ・デッドボリューム・フィッティングアッセンブリー |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US11041581B2 (enExample) |
| EP (1) | EP3759480B1 (enExample) |
| JP (1) | JP7282793B2 (enExample) |
| WO (1) | WO2019165415A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5868977B2 (ja) * | 2010-08-10 | 2016-02-24 | アイデックス ヘルス アンド サイエンス エルエルシー | 液体クロマトグラフィシステム用の生体適合性管 |
| EP3301338B1 (en) * | 2011-06-20 | 2019-07-31 | Waters Technologies Corporation | Low carryover high pressure fluidic fitting |
| EP3961208B1 (en) * | 2020-08-28 | 2025-08-06 | F. Hoffmann-La Roche AG | Sample injector |
| CN113399008B (zh) * | 2021-06-23 | 2025-04-11 | 厦门色谱分析仪器有限公司 | 通用型微纳流管道常压无死体积接口 |
| US12470010B2 (en) * | 2021-08-23 | 2025-11-11 | Te Connectivity Solutions Gmbh Et Al. | Housing having different dielectric constants |
| CN115256262A (zh) * | 2022-07-26 | 2022-11-01 | 中国电子科技集团公司第十一研究所 | 定位工具及组件的装配方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100224543A1 (en) | 2009-03-05 | 2010-09-09 | Ellis Scott J | Connection assembly for ultra high pressure liquid chromatography |
| US20120061955A1 (en) | 2009-05-22 | 2012-03-15 | Hermann Hochgraeber | Plug unit and connection system for connecting capillary tubes, especially for high-performance liquid chromatography |
| US20120319400A1 (en) | 2008-06-02 | 2012-12-20 | Optimize Technologies, Inc. | Fitting assembly |
| US20150300542A1 (en) | 2014-04-16 | 2015-10-22 | Idex Health & Science Llc | High Pressure Fluidic Connection Assemblies |
| US20180058612A1 (en) | 2010-07-16 | 2018-03-01 | Idex Health & Science Llc | Biocompatible Tubing for Liquid Chromatography Systems |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4776618A (en) * | 1987-08-14 | 1988-10-11 | Marathon Oil Company | High pressure coupling |
| US6056331A (en) | 1996-09-12 | 2000-05-02 | The Regents Of The University Of California | Zero dead volume tube to surface seal |
| US6494500B1 (en) * | 1999-05-12 | 2002-12-17 | Geoff Todosiev | Universal high pressure liquid connector |
| US7316777B2 (en) | 2005-01-28 | 2008-01-08 | Valco Instruments Co., Inc. | Compression fitting nut with interlocked ferrule |
| US9322811B2 (en) | 2012-11-12 | 2016-04-26 | Dionex Corporation | Zero dead volume robust fluidic connection system |
| US9822772B2 (en) | 2013-01-16 | 2017-11-21 | Valco Instruments Company, L.P. | Pump and injector for liquid chromatography |
| EP2946188B1 (en) | 2013-01-16 | 2019-08-21 | Valco Instruments Company, L.P. | Pump and injector for liquid chromatography |
| US9539524B2 (en) | 2013-01-16 | 2017-01-10 | Valco Instruments Company, L.P. | Pump and injector for liquid chromatography |
| DE102014100430B4 (de) * | 2014-01-15 | 2015-08-06 | Dionex Softron Gmbh | Adaptergehäuse und eine das Adaptergehäuse umfassende Verbindungseinrichtung |
| EP3828455A1 (en) | 2014-10-23 | 2021-06-02 | Idex Health & Science LLC | Face-sealing fluidic connection system |
| US10174871B2 (en) | 2016-03-04 | 2019-01-08 | Valco Instruments Company, L.P. | Zero dead volume fitting assembly |
-
2018
- 2018-07-30 US US16/048,681 patent/US11041581B2/en active Active
-
2019
- 2019-02-26 EP EP19757689.5A patent/EP3759480B1/en active Active
- 2019-02-26 WO PCT/US2019/019544 patent/WO2019165415A1/en not_active Ceased
- 2019-02-26 JP JP2020544855A patent/JP7282793B2/ja active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120319400A1 (en) | 2008-06-02 | 2012-12-20 | Optimize Technologies, Inc. | Fitting assembly |
| US20100224543A1 (en) | 2009-03-05 | 2010-09-09 | Ellis Scott J | Connection assembly for ultra high pressure liquid chromatography |
| JP2012519818A (ja) | 2009-03-05 | 2012-08-30 | アイデックス ヘルス アンド サイエンス エルエルシー | 超高圧液体クロマトグラフィーのための連結構成要素 |
| US20120061955A1 (en) | 2009-05-22 | 2012-03-15 | Hermann Hochgraeber | Plug unit and connection system for connecting capillary tubes, especially for high-performance liquid chromatography |
| US20180058612A1 (en) | 2010-07-16 | 2018-03-01 | Idex Health & Science Llc | Biocompatible Tubing for Liquid Chromatography Systems |
| US20150300542A1 (en) | 2014-04-16 | 2015-10-22 | Idex Health & Science Llc | High Pressure Fluidic Connection Assemblies |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3759480A4 (en) | 2021-11-24 |
| JP2021515152A (ja) | 2021-06-17 |
| US20190264844A1 (en) | 2019-08-29 |
| WO2019165415A1 (en) | 2019-08-29 |
| EP3759480B1 (en) | 2022-08-24 |
| EP3759480A1 (en) | 2021-01-06 |
| US11041581B2 (en) | 2021-06-22 |
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