JP7278281B2 - ニコチン錠 - Google Patents

ニコチン錠 Download PDF

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Publication number
JP7278281B2
JP7278281B2 JP2020529346A JP2020529346A JP7278281B2 JP 7278281 B2 JP7278281 B2 JP 7278281B2 JP 2020529346 A JP2020529346 A JP 2020529346A JP 2020529346 A JP2020529346 A JP 2020529346A JP 7278281 B2 JP7278281 B2 JP 7278281B2
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JP
Japan
Prior art keywords
nicotine
tablet
orally disintegrating
seconds
oral administration
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Active
Application number
JP2020529346A
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English (en)
Japanese (ja)
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JP2021505546A5 (https=
JP2021505546A (ja
Inventor
プロフストゴール ニールセン、ブルーノ
アルビン ニールセン、ケント
Original Assignee
フェルティン ファルマ アー／エス
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=64744343&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP7278281(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by フェルティン ファルマ アー／エス filed Critical フェルティン ファルマ アー／エス
Publication of JP2021505546A publication Critical patent/JP2021505546A/ja
Publication of JP2021505546A5 publication Critical patent/JP2021505546A5/ja
Application granted granted Critical
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2020529346A 2017-12-08 2018-12-07 ニコチン錠 Active JP7278281B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201770925 2017-12-08
DKPA201770925 2017-12-08
PCT/DK2018/050335 WO2019110072A1 (en) 2017-12-08 2018-12-07 Nicotine tablet

Publications (3)

Publication Number Publication Date
JP2021505546A JP2021505546A (ja) 2021-02-18
JP2021505546A5 JP2021505546A5 (https=) 2022-01-04
JP7278281B2 true JP7278281B2 (ja) 2023-05-19

Family

ID=64744343

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020529346A Active JP7278281B2 (ja) 2017-12-08 2018-12-07 ニコチン錠

Country Status (10)

Country Link
US (4) US11738016B2 (https=)
EP (2) EP3906916A1 (https=)
JP (1) JP7278281B2 (https=)
CN (1) CN111447921B (https=)
AU (1) AU2018378648B2 (https=)
CA (1) CA3085062C (https=)
DK (1) DK3720418T3 (https=)
ES (1) ES2890975T3 (https=)
PL (1) PL3720418T3 (https=)
WO (1) WO2019110072A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3085065C (en) 2017-12-08 2023-12-05 Fertin Pharma A/S Formulations providing high nicotine concentrations
WO2019110072A1 (en) 2017-12-08 2019-06-13 Fertin Pharma A/S Nicotine tablet
US12433321B2 (en) 2019-12-09 2025-10-07 Nicoventures Trading Limited Oral composition with beet material
US12439952B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Moist oral compositions
US11826462B2 (en) 2019-12-09 2023-11-28 Nicoventures Trading Limited Oral product with sustained flavor release
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
US11617744B2 (en) 2019-12-09 2023-04-04 Nico Ventures Trading Limited Moist oral compositions
US12310959B2 (en) 2019-12-09 2025-05-27 Nicoventures Trading Limited Oral compositions with reduced water content
US11969502B2 (en) 2019-12-09 2024-04-30 Nicoventures Trading Limited Oral products
US12520867B2 (en) 2019-12-09 2026-01-13 Nicoventures Trading Limited Buffered oral compositions
US11793230B2 (en) 2019-12-09 2023-10-24 Nicoventures Trading Limited Oral products with improved binding of active ingredients
US12439949B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Oral compositions with reduced water activity
CA3181912A1 (en) 2020-06-08 2021-12-16 Anthony Richard Gerardi Effervescent oral composition comprising an active ingredient
US11382861B1 (en) * 2020-12-17 2022-07-12 Nirajkumar Karneshbhai Patel Nicotine pouch
MX2023015529A (es) 2021-06-25 2024-03-05 Nicoventures Trading Ltd Productos orales y metodo de fabricacion.
JP2024530905A (ja) 2021-07-30 2024-08-27 ニコベンチャーズ トレーディング リミテッド 微結晶性セルロースを含むエアロゾル生成基材
CA3233375A1 (en) 2021-09-30 2023-04-06 Michael Zawadzki Oral product with a basic amine and an ion pairing agent
CN113827575A (zh) * 2021-11-02 2021-12-24 上海普康药业有限公司 一种利伐沙班片剂及其制备方法
CN115969898A (zh) * 2023-02-09 2023-04-18 东莞市吉纯生物技术有限公司 一种防治口腔溃疡的口含烟含片及其制备方法
EP4543417A1 (en) 2023-09-12 2025-04-30 Fertin Pharma A/S Orally disintegrating nicotine tablet for use under lip
WO2025056129A1 (en) 2023-09-12 2025-03-20 Fertin Pharma A/S Orally disintegrating nicotine tablet for use under lip
DK202430540A1 (en) 2024-09-12 2026-03-26 Fertin Pharma As Orally disintegrating nicotine tablet with reduced sweetener content
WO2026057139A1 (en) 2024-09-12 2026-03-19 Fertin Pharma A/S Fast dissolvable solid oral dosage form

Citations (8)

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WO2009007771A1 (en) 2007-07-06 2009-01-15 Gumlink A/S High volume compressed chewing gum tablet
JP2010526876A (ja) 2007-05-16 2010-08-05 マクニール アーベー アミノ酸によって緩衝化されたコーティング経口ニコチン製剤
JP2011519862A (ja) 2008-05-01 2011-07-14 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー ニコチンロゼンジ組成物
JP2012505878A (ja) 2008-10-14 2012-03-08 マクニール アーベー 複数部分口内剤形及びその使用
JP2014503539A (ja) 2010-12-22 2014-02-13 ビーエーエスエフ ソシエタス・ヨーロピア 速崩性の固体被覆剤形
US20140328973A1 (en) 2011-12-22 2014-11-06 Bruno Provstgaard Nielsen Method of releasing nicotine from chewing gum
JP2015503581A (ja) 2012-01-05 2015-02-02 マクニール・アーベーＭｃＮｅｉｌＡＢ 感覚刺激性撹乱の低減された固体ニコチン含有剤形

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WO2019110073A1 (en) 2017-12-08 2019-06-13 Fertin Pharma A/S Solid oral nicotine formulation
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Publication number Priority date Publication date Assignee Title
JP2006518761A (ja) 2003-02-24 2006-08-17 ファーマシューティカル プロダクションズ， インコーポレイテッド 経粘膜薬物送達システム
JP2010526876A (ja) 2007-05-16 2010-08-05 マクニール アーベー アミノ酸によって緩衝化されたコーティング経口ニコチン製剤
WO2009007771A1 (en) 2007-07-06 2009-01-15 Gumlink A/S High volume compressed chewing gum tablet
JP2011519862A (ja) 2008-05-01 2011-07-14 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー ニコチンロゼンジ組成物
US20130289079A1 (en) 2008-05-01 2013-10-31 GlaxoSmithKline, LLC Nicotine Lozenge Composition
JP2012505878A (ja) 2008-10-14 2012-03-08 マクニール アーベー 複数部分口内剤形及びその使用
JP2014503539A (ja) 2010-12-22 2014-02-13 ビーエーエスエフ ソシエタス・ヨーロピア 速崩性の固体被覆剤形
US20140328973A1 (en) 2011-12-22 2014-11-06 Bruno Provstgaard Nielsen Method of releasing nicotine from chewing gum
JP2015503581A (ja) 2012-01-05 2015-02-02 マクニール・アーベーＭｃＮｅｉｌＡＢ 感覚刺激性撹乱の低減された固体ニコチン含有剤形

Also Published As

Publication number Publication date
PL3720418T3 (pl) 2021-12-20
US11738016B2 (en) 2023-08-29
CN111447921A (zh) 2020-07-24
US20240285610A1 (en) 2024-08-29
EP3906916A1 (en) 2021-11-10
DK3720418T3 (da) 2021-10-11
ES2890975T3 (es) 2022-01-25
WO2019110072A1 (en) 2019-06-13
US20230346768A1 (en) 2023-11-02
CA3085062A1 (en) 2019-06-13
CN111447921B (zh) 2023-10-13
US12005058B2 (en) 2024-06-11
EP3720418B1 (en) 2021-08-04
JP2021505546A (ja) 2021-02-18
US20190175581A1 (en) 2019-06-13
EP3720418A1 (en) 2020-10-14
US20260014135A1 (en) 2026-01-15
AU2018378648A1 (en) 2020-07-23
AU2018378648B2 (en) 2021-06-03
US12433881B2 (en) 2025-10-07
CA3085062C (en) 2022-08-16

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