ES2890975T3 - Comprimido de nicotina - Google Patents

Comprimido de nicotina Download PDF

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Publication number
ES2890975T3
ES2890975T3 ES18821992T ES18821992T ES2890975T3 ES 2890975 T3 ES2890975 T3 ES 2890975T3 ES 18821992 T ES18821992 T ES 18821992T ES 18821992 T ES18821992 T ES 18821992T ES 2890975 T3 ES2890975 T3 ES 2890975T3
Authority
ES
Spain
Prior art keywords
nicotine
tablet
seconds
oral administration
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES18821992T
Other languages
English (en)
Spanish (es)
Inventor
Bruno Provstgaard Nielsen
Kent Albin Nielsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fertin Pharma AS
Original Assignee
Fertin Pharma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=64744343&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2890975(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fertin Pharma AS filed Critical Fertin Pharma AS
Application granted granted Critical
Publication of ES2890975T3 publication Critical patent/ES2890975T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES18821992T 2017-12-08 2018-12-07 Comprimido de nicotina Active ES2890975T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201770925 2017-12-08
PCT/DK2018/050335 WO2019110072A1 (en) 2017-12-08 2018-12-07 Nicotine tablet

Publications (1)

Publication Number Publication Date
ES2890975T3 true ES2890975T3 (es) 2022-01-25

Family

ID=64744343

Family Applications (1)

Application Number Title Priority Date Filing Date
ES18821992T Active ES2890975T3 (es) 2017-12-08 2018-12-07 Comprimido de nicotina

Country Status (10)

Country Link
US (4) US11738016B2 (https=)
EP (2) EP3906916A1 (https=)
JP (1) JP7278281B2 (https=)
CN (1) CN111447921B (https=)
AU (1) AU2018378648B2 (https=)
CA (1) CA3085062C (https=)
DK (1) DK3720418T3 (https=)
ES (1) ES2890975T3 (https=)
PL (1) PL3720418T3 (https=)
WO (1) WO2019110072A1 (https=)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3085065C (en) 2017-12-08 2023-12-05 Fertin Pharma A/S Formulations providing high nicotine concentrations
WO2019110072A1 (en) 2017-12-08 2019-06-13 Fertin Pharma A/S Nicotine tablet
US12433321B2 (en) 2019-12-09 2025-10-07 Nicoventures Trading Limited Oral composition with beet material
US12439952B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Moist oral compositions
US11826462B2 (en) 2019-12-09 2023-11-28 Nicoventures Trading Limited Oral product with sustained flavor release
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
US11617744B2 (en) 2019-12-09 2023-04-04 Nico Ventures Trading Limited Moist oral compositions
US12310959B2 (en) 2019-12-09 2025-05-27 Nicoventures Trading Limited Oral compositions with reduced water content
US11969502B2 (en) 2019-12-09 2024-04-30 Nicoventures Trading Limited Oral products
US12520867B2 (en) 2019-12-09 2026-01-13 Nicoventures Trading Limited Buffered oral compositions
US11793230B2 (en) 2019-12-09 2023-10-24 Nicoventures Trading Limited Oral products with improved binding of active ingredients
US12439949B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Oral compositions with reduced water activity
CA3181912A1 (en) 2020-06-08 2021-12-16 Anthony Richard Gerardi Effervescent oral composition comprising an active ingredient
US11382861B1 (en) * 2020-12-17 2022-07-12 Nirajkumar Karneshbhai Patel Nicotine pouch
MX2023015529A (es) 2021-06-25 2024-03-05 Nicoventures Trading Ltd Productos orales y metodo de fabricacion.
JP2024530905A (ja) 2021-07-30 2024-08-27 ニコベンチャーズ トレーディング リミテッド 微結晶性セルロースを含むエアロゾル生成基材
CA3233375A1 (en) 2021-09-30 2023-04-06 Michael Zawadzki Oral product with a basic amine and an ion pairing agent
CN113827575A (zh) * 2021-11-02 2021-12-24 上海普康药业有限公司 一种利伐沙班片剂及其制备方法
CN115969898A (zh) * 2023-02-09 2023-04-18 东莞市吉纯生物技术有限公司 一种防治口腔溃疡的口含烟含片及其制备方法
EP4543417A1 (en) 2023-09-12 2025-04-30 Fertin Pharma A/S Orally disintegrating nicotine tablet for use under lip
WO2025056129A1 (en) 2023-09-12 2025-03-20 Fertin Pharma A/S Orally disintegrating nicotine tablet for use under lip
DK202430540A1 (en) 2024-09-12 2026-03-26 Fertin Pharma As Orally disintegrating nicotine tablet with reduced sweetener content
WO2026057139A1 (en) 2024-09-12 2026-03-19 Fertin Pharma A/S Fast dissolvable solid oral dosage form

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4866046A (en) 1988-05-31 1989-09-12 Top Laboratories, Inc. Low-dosage sublingual aspirin
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system
US5549906A (en) 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5810018A (en) * 1994-12-29 1998-09-22 Monte; Woodrow C. Method, composition and apparatus for reducing the incidence of cigarette smoking
CA2348452A1 (en) 1998-10-27 2000-05-04 Biovail Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
US20010016593A1 (en) 1999-04-14 2001-08-23 Wilhelmsen Paul C. Element giving rapid release of nicotine for transmucosal administration
US6248760B1 (en) 1999-04-14 2001-06-19 Paul C Wilhelmsen Tablet giving rapid release of nicotine for transmucosal administration
US6583160B2 (en) 1999-04-14 2003-06-24 Steve Smith Nicotine therapy method and oral carrier for assuaging tobacco-addiction
US6544552B2 (en) 2001-01-11 2003-04-08 Particle And Coating Technologies, Inc. Method of producing porous tablets with improved dissolution properties
AU2002237548B2 (en) * 2001-03-06 2007-04-05 Kyowa Hakko Kogyo Co., Ltd. Intraorally rapidly disintegrable tablet
NZ530439A (en) 2001-04-20 2004-11-26 Lavipharm Lab Inc Intraoral delivery of nicotine for smoking cessation
US20060057207A1 (en) 2001-11-30 2006-03-16 Pfizer Inc Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene
SE0104388D0 (sv) 2001-12-27 2001-12-27 Pharmacia Ab New formulation and use and manufacture thereof
US20150080442A1 (en) 2003-02-24 2015-03-19 Pharmaceutical Productions Inc. Transmucosal drug delivery system
EP2343045A3 (en) * 2003-02-24 2011-09-21 Pharmaceutical Productions Inc. Transmucosal drug delivery system
BRPI0412752B8 (pt) 2003-07-24 2021-05-25 Glaxosmithkline Llc composição de filme de dissolução oral
US7387788B1 (en) * 2003-10-10 2008-06-17 Antares Pharma Ipl Ag Pharmaceutical compositions of nicotine and methods of use thereof
WO2005055945A2 (en) * 2003-12-08 2005-06-23 Gel-Del Technologies, Inc. Mucoadhesive drug delivery devices and methods of making and using thereof
US20070196474A1 (en) 2004-04-30 2007-08-23 Withiam Michael C Rapidly disintegrating low friability tablets comprising calcium carbonate
ES2403167T3 (es) 2005-12-21 2013-05-14 Basf Se Polivinilpirrolidona entrelazada finamente dividida como agente desintegrador de tabletas
US20070269492A1 (en) * 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
US20070269386A1 (en) 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
CN101516426A (zh) 2006-09-27 2009-08-26 尼克诺姆股份公司 定向用途
BRPI0719428A2 (pt) 2006-12-01 2014-02-25 Cima Labs Inc Forma de dosagem transmucosal oral sólida, método para tratar dependência de nicotina em um receptor que deseja tal tratamento, sistema de distribuição de nicotina transmucosal oral, e, método de substituíção de nicotina.
US20080286340A1 (en) 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
US20080286341A1 (en) 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered coated nicotine containing products
WO2009007771A1 (en) 2007-07-06 2009-01-15 Gumlink A/S High volume compressed chewing gum tablet
CL2009001025A1 (es) * 2008-05-01 2010-09-24 Smithkline Beecham Corp Composicion de pastilla para chupar que comprende: a) un granulo patron con al menos: un agente tampon alcalino, un modificador de la disolucion y una carga, b) un principio activo de nicotina definido extragranular y al menos un agente tampon alcalino; procedimiento de preparacion; util para eliminar o reducir el uso de tabaco.
SI2177213T1 (sl) 2008-09-17 2013-03-29 Siegfried Ltd. Nikotin vsebujoč granulat
ES2592882T3 (es) 2008-10-14 2016-12-02 Mcneil Ab Forma de dosificación intra-oral de múltiples porciones y uso de la misma
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
CN107252419A (zh) 2010-12-22 2017-10-17 巴斯夫欧洲公司 快速崩解的固体包衣剂型
SE535587C2 (sv) 2011-03-29 2012-10-02 Chill Of Sweden Ab Produkt innehållande ett fritt nikotinsalt och en ej vattenlöslig påse
TW201318650A (zh) 2011-11-02 2013-05-16 Hua Yu Wuxi Pharmaceutical Co Ltd 口崩片組成物
WO2013091631A1 (en) * 2011-12-22 2013-06-27 Fertin Pharma A/S Method of releasing nicotine from chewing gum
US20130177646A1 (en) 2012-01-05 2013-07-11 Mcneil Ab Solid Nicotine-Comprising Dosage Form with Reduced Organoleptic Disturbance
US11779045B2 (en) * 2013-10-03 2023-10-10 Altria Client Services Llc Dissolvable-chewable exhausted-tobacco tablet
DK3166563T3 (da) 2014-07-08 2021-02-15 Fertin Pharma As Oralt administrationssystem omfattende to rum
US20170172995A1 (en) 2015-09-08 2017-06-22 Venkateswara Rao Repaka Pharmaceutical compositions of Nicotine and process for preparation thereof
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
WO2017117575A1 (en) 2015-12-30 2017-07-06 Next Generation Labs, LLC Nicotine replacement therapy products comprising synthetic nicotine
CA3085065C (en) 2017-12-08 2023-12-05 Fertin Pharma A/S Formulations providing high nicotine concentrations
CA3085066C (en) 2017-12-08 2024-01-09 Fertin Pharma A/S Formulations providing high nicotine concentrations
WO2019110073A1 (en) 2017-12-08 2019-06-13 Fertin Pharma A/S Solid oral nicotine formulation
WO2019110072A1 (en) 2017-12-08 2019-06-13 Fertin Pharma A/S Nicotine tablet
CA3085064C (en) 2017-12-08 2023-10-24 Fertin Pharma A/S Nicotine mouth spray

Also Published As

Publication number Publication date
PL3720418T3 (pl) 2021-12-20
US11738016B2 (en) 2023-08-29
CN111447921A (zh) 2020-07-24
US20240285610A1 (en) 2024-08-29
EP3906916A1 (en) 2021-11-10
DK3720418T3 (da) 2021-10-11
WO2019110072A1 (en) 2019-06-13
US20230346768A1 (en) 2023-11-02
CA3085062A1 (en) 2019-06-13
CN111447921B (zh) 2023-10-13
US12005058B2 (en) 2024-06-11
EP3720418B1 (en) 2021-08-04
JP2021505546A (ja) 2021-02-18
US20190175581A1 (en) 2019-06-13
EP3720418A1 (en) 2020-10-14
US20260014135A1 (en) 2026-01-15
AU2018378648A1 (en) 2020-07-23
AU2018378648B2 (en) 2021-06-03
US12433881B2 (en) 2025-10-07
CA3085062C (en) 2022-08-16
JP7278281B2 (ja) 2023-05-19

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