JP7230046B2 - 体液収集装置および収集モジュール - Google Patents
体液収集装置および収集モジュール Download PDFInfo
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Description
一実施形態では、収集モジュール14は、通路36を密閉するために収集モジュール14の入口ポート32と係合するクロージャー28を含む。クロージャー28は、入口ポート32を保護的に覆うクロージャー28は、血液サンプル12をハウジング20の通路36に導入することを可能にし、ベクトン、ディキンソンおよびカンパニーから市販されているヘモガード(Hemogard)TM(商標)キャップなどの外部シールド84を備えた貫通可能なセルフシールストッパー82(図17)を含み得る。クロージャー28はまた、ベクトン、ディキンソンアンドカンパニーから市販されているVacutainer(登録商標)採血管のような真空を含む採血管であり得る外部ハウジング16に固定する。
Claims (19)
- サンプルを受け取るようになっている収集モジュールであって、
入口ポートおよび出口ポートを有し、前記入口ポートおよび前記出口ポートが流体連通しているハウジングと、
前記入口ポートと前記出口ポートの間に配置された混合チャンバーと、
前記入口ポートと前記出口ポートの間に配置されたサンプル安定剤と、を備え、
収集チャンバーが、前記混合チャンバーと前記出口ポートとの間に配置され、前記収集チャンバーは、少なくとも部分的に第1の変形可能部分および第2の変形可能部分によって規定され、前記収集チャンバーは、前記サンプルおよびその中に前記サンプル安定剤の少なくとも一部を受け入れて収容し、
前記第1の変形可能部分は、前記第2の変形可能部分と分離して対向し、前記第1の変形可能部分および前記第2の変形可能部分はそれぞれ、前記サンプルが前記収集チャンバー内に含まれる初期位置と、前記サンプルの一部が前記収集チャンバーから排出される変形位置との間で移行可能である、収集モジュール。 - 前記第1の変形可能部分および前記第2の変形可能部分が同時に圧搾されて、前記初期位置から前記変形位置に移行する、
請求項1に記載の収集モジュール。 - 前記収集チャンバーは、前記第1の変形可能部分と前記第2の変形可能部分との間に剛性壁部分をさらに備える、
請求項1に記載の収集モジュール。 - 前記混合チャンバーが、
第1の入口端と第1の出口端とを有する第1の湾曲した壁と、
第2の入口端および第2の出口端を有する第2の湾曲した壁と、を備え、
前記第1の入口端部は、前記第2の入口端部から第1の距離だけ離れており、
前記第1の出口端は、前記第2の出口端から第2の距離だけ離間され、前記第2の距離は、前記第1の距離よりも短い、
請求項1に記載の収集モジュール。 - 前記入口ポートと前記混合チャンバーとの間に配置された細孔を含む材料を備え、
前記材料は前記細孔内の乾燥した抗凝固剤粉末を含む、
請求項1に記載の収集モジュール。 - 前記サンプルが、前記材料を通過する間に、溶解し、前記乾燥抗凝固剤粉末と混合する、
請求項5に記載の収集モジュール。 - 前記材料が連続気泡フォームである、
請求項5に記載の収集モジュール。 - 前記サンプル安定剤が前記乾燥抗凝固剤粉末である、
請求項5に記載の収集モジュール。 - 前記入口ポートを覆うクロージャーをさらに含む、
請求項1に記載の収集モジュール。 - 前記出口ポートを覆い、空気がそこを通過することを可能にし、前記サンプルがそこを通過することを防止する通気プラグを有するキャップをさらに備える、
請求項1に記載の収集モジュール。 - 請求項1に記載の前記収集モジュールと、
前記収集モジュールに取り外し可能に接続可能な外部ハウジングと、を備え、
前記収集モジュールは、前記外部ハウジングに接続された状態で、前記収集モジュールは前記外部ハウジング内に配置される、
生体液収集デバイス。 - サンプルを受け取るようになっている収集モジュールであって、
前記収集モジュールは、
入口ポートおよび出口ポートを有し、前記入口ポートおよび前記出口ポートが流体連通しているハウジングと、
前記入口ポートと前記出口ポートの間に配置された混合チャンバーと、
前記入口ポートと前記混合チャンバーの間に配置されたサンプル安定剤と、
前記混合チャンバーと前記出口ポートの間に配置された収集チャンバーと、を備え、
前記収集チャンバーは、
前記サンプルを受け取る剛性壁のチャンバーと、
空気を含む変形可能な部分であって、前記剛性壁チャンバーの外部にある前記変形可能な部分と、
前記剛性壁チャンバーと前記変形可能部分の間の一方向弁と、を備え、
前記変形可能部分は、前記サンプルが前記剛性壁チャンバー内に含まれる初期位置と、前記サンプルの一部が前記剛性壁チャンバーから排出される変形位置との間で移行可能であり、
前記一方向弁は、前記サンプルが前記剛性壁チャンバーから前記変形可能部分に移動するのを防ぎ、空気が前記変形可能部分から前記剛性壁チャンバーに移動して、前記サンプルを前記剛性壁チャンバーから排出することを可能にする、
収集モジュール。 - 前記変形可能部分が袋(bladder)を含む、
請求項12に記載の収集モジュール。 - 前記混合チャンバーがその中に前記サンプルおよび前記サンプル安定剤を受け入れる、請求項12に記載の収集モジュール。
- 前記混合チャンバーは、
第1の入口端と第1の出口端とを有する第1の湾曲した壁と、
第2の入口端および第2の出口端を有する第2の湾曲した壁と、を備え、
前記第1の入口端部は、前記第2の入口端部から第1の距離だけ離れており、
前記第1の出口端は、前記第2の出口端から第2の距離だけ離間され、前記第2の距離は、前記第1の距離よりも短い、
請求項12に記載の収集モジュール。 - 前記入口ポートと前記混合チャンバーとの間に配置された細孔を含む材料と、
前記材料の前記細孔内の乾燥した抗凝固剤粉末と、を備える、
請求項12に記載の収集モジュール。 - 前記サンプルは、前記材料を通過する間に、溶解し、前記乾燥抗凝固剤粉末と混合する、
請求項16に記載の収集モジュール。 - 前記材料が連続気泡フォームである、
請求項16に記載の収集モジュール。 - 前記サンプル安定剤が前記乾燥抗凝固剤粉末である、
請求項16に記載の収集モジュール。
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Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USD889685S1 (en) | 2016-03-18 | 2020-07-07 | Meso Scale Technologies, Llc. | Reagent rack cover |
USD940893S1 (en) * | 2019-08-08 | 2022-01-11 | American Laboratory Products Company, Ltd. | Extraction device |
US10877022B1 (en) * | 2020-02-14 | 2020-12-29 | Taiwan Redeye Biomedical Inc. | Occult blood testing device |
USD965174S1 (en) * | 2020-07-17 | 2022-09-27 | Zymo Research Corporation | Specimen collection tube |
US20230277105A1 (en) * | 2022-03-07 | 2023-09-07 | Becton, Dickinson And Company | Blood Access Device with Integrated Blood Diagnostics |
WO2023172538A2 (en) * | 2022-03-08 | 2023-09-14 | Becton, Dickinson And Company | Small sample collection and dispensing device for use with luer lock access device and point-of-care diagnostics |
JP1733746S (ja) * | 2022-04-11 | 2023-01-05 | 検査器具 | |
USD1026246S1 (en) * | 2022-06-24 | 2024-05-07 | Zhejiang Orient Gene Biotech Co., LTD | Specimen collecting device |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2016518921A (ja) | 2013-04-15 | 2016-06-30 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 体液採取用の医療デバイス |
US20170059550A1 (en) | 2015-09-01 | 2017-03-02 | Becton, Dickinson And Company | Depth Filtration Device for Separating Specimen Phases |
JP2017531782A (ja) | 2015-03-10 | 2017-10-26 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 生物体液の極微標本管理装置 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3965889A (en) | 1971-11-26 | 1976-06-29 | Commissariat A L'energie Atomique | Apparatus for the sampling of blood and the separation of plasma under anaerobic conditions |
US5007892A (en) * | 1989-03-20 | 1991-04-16 | Eastman Kodak Company | Phase separation container with fixed means preventing remixing |
US6869405B2 (en) * | 2001-03-30 | 2005-03-22 | Becton, Dickinson And Company | Blunt cannula and filter assembly and method of use with point-of-care testing cartridge |
US7753892B2 (en) | 2001-11-13 | 2010-07-13 | Nypro Inc. | Anti-drawback medical valve |
US7090646B2 (en) * | 2003-09-09 | 2006-08-15 | Westmed, Inc. | Plunger-less syringe for controlling blood flow |
EP3685748A1 (en) | 2008-03-05 | 2020-07-29 | Becton, Dickinson and Company | Capillary action collection container assembly |
US8383044B2 (en) * | 2009-07-09 | 2013-02-26 | Becton, Dickinson And Company | Blood sampling device |
US9028425B2 (en) * | 2010-07-15 | 2015-05-12 | Becton, Dickinson And Company | Vented blood sampling device |
JP2014530358A (ja) * | 2011-09-25 | 2014-11-17 | セラノス, インコーポレイテッド | 多重分析のためのシステム及び方法 |
BR112015026248B1 (pt) * | 2013-04-15 | 2022-10-18 | Becton, Dickinson And Company | Dispositivo de coleta de fluido biológico e sistema de teste e separação de amostra de fluido biológico |
CA3005826C (en) * | 2013-04-15 | 2021-11-23 | Becton, Dickinson And Company | Biological fluid collection device and biological fluid separation and testing system |
US9597028B2 (en) * | 2013-04-15 | 2017-03-21 | Becton, Dickinson And Company | Biological fluid collection device and biological fluid separation and testing system |
CN113229813B (zh) * | 2015-06-19 | 2024-07-23 | 贝克顿·迪金森公司 | 生物流体收集装置 |
CN112971779A (zh) * | 2015-08-06 | 2021-06-18 | 贝克顿·迪金森公司 | 生物流体收集装置和生物流体收集系统 |
WO2017190192A1 (en) * | 2016-05-04 | 2017-11-09 | Bacala Innovations Pty Ltd | Fluid sampling device and method for using same |
US11779315B2 (en) * | 2016-07-22 | 2023-10-10 | Tetracore, Inc. | Self-contained sampling device for processing whole blood |
-
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2016518921A (ja) | 2013-04-15 | 2016-06-30 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 体液採取用の医療デバイス |
JP2017531782A (ja) | 2015-03-10 | 2017-10-26 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | 生物体液の極微標本管理装置 |
US20170059550A1 (en) | 2015-09-01 | 2017-03-02 | Becton, Dickinson And Company | Depth Filtration Device for Separating Specimen Phases |
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