JP7212943B2 - がん遺伝子の転写調節領域 - Google Patents

がん遺伝子の転写調節領域 Download PDF

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JP7212943B2
JP7212943B2 JP2019525586A JP2019525586A JP7212943B2 JP 7212943 B2 JP7212943 B2 JP 7212943B2 JP 2019525586 A JP2019525586 A JP 2019525586A JP 2019525586 A JP2019525586 A JP 2019525586A JP 7212943 B2 JP7212943 B2 JP 7212943B2
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sequence
binding
dna
substance
runx3
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JPWO2018230731A1 (ja
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公成 伊藤
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Nagasaki University
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Nagasaki University
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/18—Water

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019525586A 2017-06-16 2018-06-15 がん遺伝子の転写調節領域 Active JP7212943B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2017119159 2017-06-16
JP2017119159 2017-06-16
PCT/JP2018/023028 WO2018230731A1 (fr) 2017-06-16 2018-06-15 Région de commande de transcription d'oncogène

Publications (2)

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JPWO2018230731A1 JPWO2018230731A1 (ja) 2020-04-16
JP7212943B2 true JP7212943B2 (ja) 2023-01-26

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JP2019525586A Active JP7212943B2 (ja) 2017-06-16 2018-06-15 がん遺伝子の転写調節領域

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JP (1) JP7212943B2 (fr)
WO (1) WO2018230731A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6727680B2 (ja) * 2018-03-26 2020-07-22 国立大学法人神戸大学 細胞の有する二本鎖ｄｎａの標的部位を改変する方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JACOBS, Paejonette T. et al.，Runx Transcription Factors Repress Human and Murine c-Myc Expression in a DNA-Binding and C-Terminally Dependent Manner，PLoS ONE，2013年，Vol.8(7):e69083，pp.1-16，doi:10.1371/journal.pone.0069083, ISSN:1932-6203, 特に図１、２
LEE, Cecilia Wei Lin et al.，Role of RUNX3 in Bone Morphogenetic Protein Signaling in Colorectal Cancer，Cancer Research，2010年，Vol.70(10)，pp.4243-4252，ISSN:0008-5472, 特にアブストラクト、図４
MORITA, Ken et al.，Genetic regulation of the RUNX transcription factor family has antitumor effects，The Journal of Clinical Investigation，2017年05月22日，Vol.127(7)，pp.2815-2828，ISSN:0021-9738, 特にアブストラクト、図４、５、サプリメンタル図１７
SHIN, Min Hwa et al.，A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells，PLoS Genet.，2016年，Vol.12(2):e1005884，pp.1-25，doi:10.1371/journal.pgen.1005884, ISSN:1553-7390, 特にアブストラクト、図１～９

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JPWO2018230731A1 (ja) 2020-04-16
WO2018230731A1 (fr) 2018-12-20

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