JP7206570B2 - 分析装置 - Google Patents

分析装置 Download PDF

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Publication number
JP7206570B2
JP7206570B2 JP2020536620A JP2020536620A JP7206570B2 JP 7206570 B2 JP7206570 B2 JP 7206570B2 JP 2020536620 A JP2020536620 A JP 2020536620A JP 2020536620 A JP2020536620 A JP 2020536620A JP 7206570 B2 JP7206570 B2 JP 7206570B2
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light
sample
photodetector
excitation
light source
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Japanese (ja)
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JP2021514051A (ja
JPWO2019159109A5 (https=
JP2021514051A5 (https=
Inventor
デビッド ブッカー，
マイケル ヘイル，
ラジ シリクリシュナン，
マーク メイヤーニック，
シャオペイ ファン，
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プロサイズディーエックス インコーポレーテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1734—Sequential different kinds of measurements; Combining two or more methods
    • G01N2021/1736—Sequential different kinds of measurements; Combining two or more methods with two or more light sources
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1738—Optionally different kinds of measurements; Method being valid for different kinds of measurement
    • G01N2021/174—Optionally different kinds of measurements; Method being valid for different kinds of measurement either absorption-reflection or emission-fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6471—Special filters, filter wheel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2020536620A 2018-02-15 2019-02-14 分析装置 Active JP7206570B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862631165P 2018-02-15 2018-02-15
US62/631,165 2018-02-15
PCT/IB2019/051213 WO2019159109A1 (en) 2018-02-15 2019-02-14 Analyzer

Publications (4)

Publication Number Publication Date
JP2021514051A JP2021514051A (ja) 2021-06-03
JPWO2019159109A5 JPWO2019159109A5 (https=) 2022-02-18
JP2021514051A5 JP2021514051A5 (https=) 2022-02-18
JP7206570B2 true JP7206570B2 (ja) 2023-01-18

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JP2020536620A Active JP7206570B2 (ja) 2018-02-15 2019-02-14 分析装置

Country Status (5)

Country Link
US (1) US11119043B2 (https=)
EP (1) EP3752819B1 (https=)
JP (1) JP7206570B2 (https=)
ES (1) ES2956109T3 (https=)
WO (1) WO2019159109A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3990894A1 (en) 2019-06-28 2022-05-04 ProciseDx Inc. Methods for accommodating for sample matrix effects in light measurement assays
JP7712365B2 (ja) * 2021-07-20 2025-07-23 株式会社日立ハイテク 分析方法および分析装置
JP2025506770A (ja) * 2022-02-23 2025-03-13 メソ スケール テクノロジーズ エルエルシー 光学センサベースのシステムのダイナミックレンジを増加させるための方法及びデバイス
CN114923885B (zh) * 2022-04-13 2025-05-16 奥谱天成（厦门）光电有限公司 一种原位超微量、荧光、浊度多功能液滴测量平台
WO2025089022A1 (ja) * 2023-10-25 2025-05-01 株式会社日立ハイテク 自動分析装置

Citations (7)

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CN102519881A (zh) 2011-12-29 2012-06-27 北京国科华仪科技有限公司 适用于吸收光检测和荧光检测的光学检测系统
JP2013512450A (ja) 2009-11-30 2013-04-11 バイオ−ラッド ラボラトリーズ，インコーポレイティド ビーズリーダ
JP2014081391A (ja) 2004-11-04 2014-05-08 Applied Biosystems Llc 熱補償型発光ダイオードを備える、光学走査システム
JP2015017940A (ja) 2013-07-12 2015-01-29 株式会社ニコン 検出方法、検出装置、バイオチップのスクリーニング方法、スクリーニング装置及びバイオチップ
JP2016510412A (ja) 2013-02-15 2016-04-07 ファウベーエム ゲゼルシャフト ミット ベシュレンクテルハフツング 濃度を決定するための方法及び装置
JP2017536550A (ja) 2014-11-25 2017-12-07 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 吸光度測定装置への蛍光検出機能の統合
US20200086312A1 (en) 2008-09-23 2020-03-19 Bio-Rad Laboratories, Inc. Detection method for a target nucleic acid

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US5077480B1 (en) * 1988-08-22 1996-07-02 United Sciences Inc Transmissometer having solid state light source
JPH04138343A (ja) * 1990-09-28 1992-05-12 Shimadzu Corp 分光螢光光度計
US6515113B2 (en) 1999-02-18 2003-02-04 The Regents Of The University Of California Phthalamide lanthanide complexes for use as luminescent markers
WO2000048991A1 (en) 1999-02-18 2000-08-24 The Regents Of The University Of California Salicylamide-lanthanide complexes for use as luminescent markers
US7283230B2 (en) * 1999-09-24 2007-10-16 Cao Group, Inc Semiconductor forensic light kit
WO2001055701A1 (en) * 2000-01-31 2001-08-02 Board Of Regents, The University Of Texas System System and method for the analysis of bodily fluids
US20060041385A1 (en) * 2004-08-18 2006-02-23 Bauer Kenneth D Method of quantitating proteins and genes in cells using a combination of immunohistochemistry and in situ hybridization
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EP2203735A4 (en) * 2007-10-29 2012-03-21 Ca Nat Research Council METHOD AND DEVICE FOR DETECTING PARTICULARLY BONDED FLUOROPHORS IMPEDED BY PARTICULAR CASES
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BR112013010096B1 (pt) * 2010-11-01 2020-03-10 3M Innovative Properties Company Método de detecção de uma atividade biológica
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Publication number Priority date Publication date Assignee Title
JP2014081391A (ja) 2004-11-04 2014-05-08 Applied Biosystems Llc 熱補償型発光ダイオードを備える、光学走査システム
US20200086312A1 (en) 2008-09-23 2020-03-19 Bio-Rad Laboratories, Inc. Detection method for a target nucleic acid
JP2013512450A (ja) 2009-11-30 2013-04-11 バイオ−ラッド ラボラトリーズ，インコーポレイティド ビーズリーダ
CN102519881A (zh) 2011-12-29 2012-06-27 北京国科华仪科技有限公司 适用于吸收光检测和荧光检测的光学检测系统
JP2016510412A (ja) 2013-02-15 2016-04-07 ファウベーエム ゲゼルシャフト ミット ベシュレンクテルハフツング 濃度を決定するための方法及び装置
JP2015017940A (ja) 2013-07-12 2015-01-29 株式会社ニコン 検出方法、検出装置、バイオチップのスクリーニング方法、スクリーニング装置及びバイオチップ
JP2017536550A (ja) 2014-11-25 2017-12-07 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 吸光度測定装置への蛍光検出機能の統合

Also Published As

Publication number Publication date
EP3752819A1 (en) 2020-12-23
EP3752819B1 (en) 2023-08-09
EP3752819C0 (en) 2023-08-09
JP2021514051A (ja) 2021-06-03
WO2019159109A1 (en) 2019-08-22
US20200225158A1 (en) 2020-07-16
US11119043B2 (en) 2021-09-14
ES2956109T3 (es) 2023-12-13

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