JP7198757B2 - ミオスタチン活性化の阻害により代謝疾患を処置するための方法 - Google Patents

ミオスタチン活性化の阻害により代謝疾患を処置するための方法 Download PDF

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JP7198757B2
JP7198757B2 JP2019536836A JP2019536836A JP7198757B2 JP 7198757 B2 JP7198757 B2 JP 7198757B2 JP 2019536836 A JP2019536836 A JP 2019536836A JP 2019536836 A JP2019536836 A JP 2019536836A JP 7198757 B2 JP7198757 B2 JP 7198757B2
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antigen
myostatin
antibody
muscle
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JP2020514295A (ja
JP2020514295A5 (cg-RX-API-DMAC10.html
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アドリアナ ドノヴァン
ミッシェル ストラウブ
ステファン ワウェルシック
ユン チョン
ミカ ウェブスター
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Scholar Rock Inc
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JP2019536836A 2017-01-06 2018-01-05 ミオスタチン活性化の阻害により代謝疾患を処置するための方法 Active JP7198757B2 (ja)

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JP2022175995A JP2023012515A (ja) 2017-01-06 2022-11-02 ミオスタチン活性化の阻害により代謝疾患を処置するための方法
JP2024189463A JP2025020230A (ja) 2017-01-06 2024-10-29 ミオスタチン活性化の阻害により代謝疾患を処置するための方法

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US201762443455P 2017-01-06 2017-01-06
US62/443,455 2017-01-06
EP17150586 2017-01-06
EP17150586.0 2017-01-06
US201762530311P 2017-07-10 2017-07-10
US62/530,311 2017-07-10
US201762608069P 2017-12-20 2017-12-20
US62/608,069 2017-12-20
PCT/US2018/012686 WO2018129395A1 (en) 2017-01-06 2018-01-05 Methods for treating metabolic diseases by inhibiting myostatin activation

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WO2016073853A1 (en) 2014-11-06 2016-05-12 Scholar Rock, Inc. Anti-pro/latent-myostatin antibodies and uses thereof
EA038146B1 (ru) 2015-09-15 2021-07-13 Сколар Рок, Инк. Антитела к про-/латентному миостатину и их применения
CN115814077A (zh) 2016-01-08 2023-03-21 供石公司 抗-原肌生长抑制素/潜伏肌生长抑制素抗体及其使用方法
DK4358995T3 (da) * 2021-06-23 2026-02-02 Scholar Rock Inc Myostatin-vej-hæmmer i kombination med en glp-1-vej-aktivator til brug ved behandling af metaboliske forstyrrelser
CN120677175A (zh) 2022-12-22 2025-09-19 供石公司 肌生成抑制蛋白活化的选择性和强效抑制剂
WO2025243299A1 (en) * 2024-05-20 2025-11-27 Technion Research & Development Foundation Limited Nutrient-based formulations usable in treating muscle atrophy
TW202617762A (zh) * 2024-07-04 2026-05-01 大陸商江蘇恆瑞醫藥股份有限公司 特異性結合潛伏肌生長抑制素的抗原結合分子及其醫藥用途

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