JP7198197B2 - 睡眠障害の治療及び予防 - Google Patents

睡眠障害の治療及び予防 Download PDF

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Publication number
JP7198197B2
JP7198197B2 JP2019503994A JP2019503994A JP7198197B2 JP 7198197 B2 JP7198197 B2 JP 7198197B2 JP 2019503994 A JP2019503994 A JP 2019503994A JP 2019503994 A JP2019503994 A JP 2019503994A JP 7198197 B2 JP7198197 B2 JP 7198197B2
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compound
sleep
formula
pharmaceutically acceptable
acceptable salt
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JP2019523269A (ja
Inventor
シー． ハリス，スティーブン
ピー． カピル，ラム
ジェイ． カイル，ドナルド
ホワイトサイド，ガース
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Purdue Pharma LP
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Purdue Pharma LP
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Acoustics & Sound (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP2019503994A 2016-07-26 2017-07-25 睡眠障害の治療及び予防 Active JP7198197B2 (ja)

Priority Applications (1)

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JP2021072166A JP7291172B2 (ja) 2016-07-26 2021-04-21 睡眠障害の治療及び予防

Applications Claiming Priority (5)

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US201662366960P 2016-07-26 2016-07-26
US62/366,960 2016-07-26
US201762536097P 2017-07-24 2017-07-24
US62/536,097 2017-07-24
PCT/IB2017/054506 WO2018020418A1 (en) 2016-07-26 2017-07-25 Treatment and prevention of sleep disorders

Related Child Applications (1)

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JP2021072166A Division JP7291172B2 (ja) 2016-07-26 2021-04-21 睡眠障害の治療及び予防

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JP2019523269A JP2019523269A (ja) 2019-08-22
JP7198197B2 true JP7198197B2 (ja) 2022-12-28

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JP2019503994A Active JP7198197B2 (ja) 2016-07-26 2017-07-25 睡眠障害の治療及び予防
JP2021072166A Active JP7291172B2 (ja) 2016-07-26 2021-04-21 睡眠障害の治療及び予防

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Country Link
US (4) US10974081B2 (https=)
EP (1) EP3490563A1 (https=)
JP (2) JP7198197B2 (https=)
KR (2) KR102210209B1 (https=)
CN (1) CN109689058B (https=)
AU (2) AU2017304898B2 (https=)
BR (1) BR112019001457A2 (https=)
CA (1) CA3031388C (https=)
CL (1) CL2019000190A1 (https=)
EC (1) ECSP19014247A (https=)
IL (1) IL264294B (https=)
JO (1) JOP20190008A1 (https=)
MX (1) MX388469B (https=)
NZ (1) NZ750817A (https=)
PH (1) PH12019500177A1 (https=)
SG (1) SG11201900486WA (https=)
TN (1) TN2019000019A1 (https=)
TW (1) TWI661827B (https=)
WO (1) WO2018020418A1 (https=)
ZA (1) ZA201901055B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190008A1 (ar) 2016-07-26 2019-01-24 Purdue Pharma Lp علاج ومنع اضطرابات النوم
JP7108041B2 (ja) * 2018-01-24 2022-07-27 パーデュー、ファーマ、リミテッド、パートナーシップ 睡眠障害の治療及び予防
CA3097445A1 (en) * 2018-04-16 2019-10-24 Technologies Hop-Child, Inc. Systems and methods for the determination of arousal states, calibrated communication signals and monitoring arousal states
KR102198846B1 (ko) * 2018-06-29 2021-01-05 다인기술 주식회사 배뇨에 관한 설문을 수행하는 방법, 시스템 및 비일시성의 컴퓨터 판독 가능 기록 매체
US11547350B2 (en) 2018-12-26 2023-01-10 Industrial Technology Research Institute Personalized parameter learning method, sleep-aid device and non-transitory computer readable medium
CN111359074B (zh) * 2018-12-26 2022-08-02 财团法人工业技术研究院 个人化参数学习方法、睡眠辅助装置及存储介质
CN113301957A (zh) * 2019-01-31 2021-08-24 普渡制药公司 取代的喹喔啉型桥接哌啶化合物的多晶型形式
BR112022004576A2 (pt) * 2019-09-13 2022-06-14 Takeda Pharmaceuticals Co Métodos para diminuir ou tratar sonolência excessiva, tratar narcolepsia tipo 2 ou hipersonia idiopática, tratar distúrbio de trabalho de turno, aumentar latência de sono em manutenção de teste de insônia, melhorar classificação de escaça de sonolência de karolinska, diminuir ou melhorar sonolência subjetiva, aumentar insônia ou diminuir sonolência excessiva, melhorar classificação de escala de sonolência epworth, tratar narcolepsia tipo 2, diminuir ou tratar sonolência diurna excessiva, e, composição farmacêutica
CN114159568B (zh) * 2020-09-11 2025-08-01 北京原基华毅生物科技有限公司 Sik抑制剂在制备用于预防和/或治疗睡眠障碍的药物中的应用
MX2023013514A (es) 2021-05-21 2024-04-02 Purdue Pharma Lp Metodos para tratar la cistitis intersticial/sindrome de dolor en la vejiga.
TWI804037B (zh) 2021-11-02 2023-06-01 長庚醫療財團法人高雄長庚紀念醫院 生酮飲食之評估系統及其運作方法
KR20250026332A (ko) * 2022-06-24 2025-02-25 퍼듀 퍼머 엘피 과민성 방광 증후군의 치료 또는 예방 방법
WO2025085818A1 (en) 2023-10-19 2025-04-24 Purdue Pharma L.P. Sunobinop for use in method of treating alcohol use disorder

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006025267A1 (ja) 2004-08-31 2006-03-09 Mitsubishi Pharma Corporation Per2タンパク質レベルの低下を作用機序とする睡眠障害治療薬
JP4056977B2 (ja) 2002-03-29 2008-03-05 田辺三菱製薬株式会社 睡眠障害治療薬
JP2011528707A (ja) 2008-07-21 2011-11-24 パーデュー、ファーマ、リミテッド、パートナーシップ 置換キノキサリンタイプ架橋ピペリジン化合物とその使用
WO2014102592A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Oxime/substituted quinoxaline-type piperidine compounds and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en) 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5733566A (en) 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
US5698155A (en) 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5591767A (en) 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
ES2247604T3 (es) 1995-06-12 2006-03-01 G.D. SEARLE & CO. Composiciones que comprenden un inhibidor de ciclooxigenasa-2 y un inhibidor de 5-lipoxigenasa.
US6572891B1 (en) 1999-10-23 2003-06-03 Alkaloid Ad Sublingual oral dosage form
JP4739217B2 (ja) 2003-05-07 2011-08-03 サムヤン コーポレイション 速く溶ける錠剤を製造するための高可塑性顆粒
AR045939A1 (es) 2003-09-25 2005-11-16 Solvay Pharm Bv Derivados de bencimidazolona y quinazolinona como agonistas de los receptores orl 1 humanos
US7355045B2 (en) 2004-01-05 2008-04-08 Applera Corporation Isotopically enriched N-substituted piperazine acetic acids and methods for the preparation thereof
WO2008033024A2 (en) 2006-09-15 2008-03-20 Echo Pharmaceuticals B.V. Dosage unit for sublingual, buccal or oral administration of water-insoluble pharmaceutically active substances
MY150602A (en) * 2007-08-31 2014-01-30 Purdue Pharma Lp Subtituted-quinoxaline-type piperidine compounds and the uses thereof
TWI441658B (zh) 2008-03-11 2014-06-21 Takeda Pharmaceutical 口腔崩解固體製劑
AU2012324015A1 (en) 2011-12-01 2013-06-20 Purdue Pharma L.P. Azetidine-substituted quinoxaline-type piperidine compounds and uses thererof
US10118927B2 (en) * 2012-12-27 2018-11-06 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
JOP20190008A1 (ar) 2016-07-26 2019-01-24 Purdue Pharma Lp علاج ومنع اضطرابات النوم

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4056977B2 (ja) 2002-03-29 2008-03-05 田辺三菱製薬株式会社 睡眠障害治療薬
WO2006025267A1 (ja) 2004-08-31 2006-03-09 Mitsubishi Pharma Corporation Per2タンパク質レベルの低下を作用機序とする睡眠障害治療薬
JP2011528707A (ja) 2008-07-21 2011-11-24 パーデュー、ファーマ、リミテッド、パートナーシップ 置換キノキサリンタイプ架橋ピペリジン化合物とその使用
WO2014102592A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Oxime/substituted quinoxaline-type piperidine compounds and uses thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
（社）日本化学会編集「光学異性体の分離〔季刊 化学総説Ｎｏ．６〕」，１９９９年６月１０日 ３刷，（株）学会出版センター，ｐ．２１２－２１８
Ｂｒｉｔｉｓｈ Ｊｏｕｒｎａｌ ｏｆ Ｐｈａｒｍａｃｏｌｏｇｙ，２００５年，Ｖｏｌ．１４６，ｐ．３３－４０
津田嘉典ら著「薬品化学（改訂第４版）」，１９８７年３月２５日 第４版１刷，（株）南江堂，ｐ．２５７－２５９

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PH12019500177A1 (en) 2019-10-14
CA3031388A1 (en) 2018-02-01
AU2017304898A1 (en) 2019-03-07
KR102210209B1 (ko) 2021-02-01
TW201817423A (zh) 2018-05-16
MX388469B (es) 2025-03-20
CL2019000190A1 (es) 2019-06-07
KR102531366B1 (ko) 2023-05-12
ZA201901055B (en) 2019-12-18
CN109689058A (zh) 2019-04-26
SG11201900486WA (en) 2019-02-27
WO2018020418A1 (en) 2018-02-01
AU2017304898B2 (en) 2020-08-20
US20190282836A1 (en) 2019-09-19
ECSP19014247A (es) 2019-05-31
US10974081B2 (en) 2021-04-13
NZ750817A (en) 2020-07-31
US11738023B2 (en) 2023-08-29
US20240058333A1 (en) 2024-02-22
AU2020273332B2 (en) 2022-11-24
CA3031388C (en) 2023-02-14
US20210330994A1 (en) 2021-10-28
TN2019000019A1 (en) 2020-07-15
KR20210013319A (ko) 2021-02-03
JP7291172B2 (ja) 2023-06-14
JP2021120379A (ja) 2021-08-19
AU2020273332A1 (en) 2020-12-17
US12370191B2 (en) 2025-07-29
MX2019001036A (es) 2019-06-10
IL264294A (en) 2019-02-28
BR112019001457A2 (pt) 2019-05-07
IL264294B (en) 2022-06-01
TWI661827B (zh) 2019-06-11
US20260007660A1 (en) 2026-01-08
CN109689058B (zh) 2022-03-22
JP2019523269A (ja) 2019-08-22
KR20190029682A (ko) 2019-03-20
EP3490563A1 (en) 2019-06-05
JOP20190008A1 (ar) 2019-01-24

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