JP7198184B2 - 内視鏡、蛍光測定装置およびレンズ保持筒状体 - Google Patents

内視鏡、蛍光測定装置およびレンズ保持筒状体 Download PDF

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Publication number
JP7198184B2
JP7198184B2 JP2019172575A JP2019172575A JP7198184B2 JP 7198184 B2 JP7198184 B2 JP 7198184B2 JP 2019172575 A JP2019172575 A JP 2019172575A JP 2019172575 A JP2019172575 A JP 2019172575A JP 7198184 B2 JP7198184 B2 JP 7198184B2
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fluorescence
endoscope
light
excitation light
objective lens
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JP2021048953A (ja
Inventor
孝夫 桜井
裕明 里村
則之 増田
伸 増田
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Advantest Corp
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Advantest Corp
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Priority to JP2019172575A priority Critical patent/JP7198184B2/ja
Priority to TW109116591A priority patent/TW202128073A/zh
Priority to PCT/JP2020/022800 priority patent/WO2021059611A1/ja
Priority to DE112020003560.3T priority patent/DE112020003560T5/de
Priority to CN202080061132.9A priority patent/CN114303054A/zh
Priority to KR1020227004360A priority patent/KR20220031688A/ko
Publication of JP2021048953A publication Critical patent/JP2021048953A/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/07Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00165Optical arrangements with light-conductive means, e.g. fibre optics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/063Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements for monochromatic or narrow-band illumination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0661Endoscope light sources
    • A61B1/0669Endoscope light sources at proximal end of an endoscope
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/12Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with cooling or rinsing arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/2407Optical details
    • G02B23/2423Optical details of the distal end
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes
    • G02B23/26Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes using light guides
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/0006Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00 with means to keep optical surfaces clean, e.g. by preventing or removing dirt, stains, contamination, condensation
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00Optical elements other than lenses
    • G02B5/20Filters
    • G02B5/208Filters for use with infrared or ultraviolet radiation, e.g. for separating visible light from infrared and/or ultraviolet radiation
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00Optical elements other than lenses
    • G02B5/30Polarising elements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/313Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes
    • A61B1/3132Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for introducing through surgical openings, e.g. laparoscopes for laparoscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6467Axial flow and illumination
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6471Special filters, filter wheel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6478Special lenses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6482Sample cells, cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6484Optical fibres

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Astronomy & Astrophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Endoscopes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
JP2019172575A 2019-09-24 2019-09-24 内視鏡、蛍光測定装置およびレンズ保持筒状体 Active JP7198184B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2019172575A JP7198184B2 (ja) 2019-09-24 2019-09-24 内視鏡、蛍光測定装置およびレンズ保持筒状体
TW109116591A TW202128073A (zh) 2019-09-24 2020-05-19 內視鏡、螢光測定裝置及透鏡保持筒狀體
PCT/JP2020/022800 WO2021059611A1 (ja) 2019-09-24 2020-06-10 内視鏡、蛍光測定装置およびレンズ保持筒状体
DE112020003560.3T DE112020003560T5 (de) 2019-09-24 2020-06-10 Endoskop, fluorophotometrische apparatur und linsenhaltender röhrenförmiger körper
CN202080061132.9A CN114303054A (zh) 2019-09-24 2020-06-10 内窥镜、荧光测定装置及透镜保持筒状体
KR1020227004360A KR20220031688A (ko) 2019-09-24 2020-06-10 내시경, 형광 측정 장치 및 렌즈 유지 통형상체

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Application Number Priority Date Filing Date Title
JP2019172575A JP7198184B2 (ja) 2019-09-24 2019-09-24 内視鏡、蛍光測定装置およびレンズ保持筒状体

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JP2021048953A JP2021048953A (ja) 2021-04-01
JP7198184B2 true JP7198184B2 (ja) 2022-12-28

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JP (1) JP7198184B2 (zh)
KR (1) KR20220031688A (zh)
CN (1) CN114303054A (zh)
DE (1) DE112020003560T5 (zh)
TW (1) TW202128073A (zh)
WO (1) WO2021059611A1 (zh)

Citations (7)

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Publication number Priority date Publication date Assignee Title
JP2005077436A (ja) 2003-08-29 2005-03-24 Precise Gauges Co Ltd 調芯方法及びその装置、並びに、これを用いた光学モジュールの製造方法及びその装置
JP2010142570A (ja) 2008-12-22 2010-07-01 Hoya Corp 内視鏡光学系
WO2010143402A1 (ja) 2009-06-09 2010-12-16 株式会社フジクラ 光学装置、レーザ照射装置およびレーザ治療装置
WO2012176720A1 (ja) 2011-06-20 2012-12-27 コニカミノルタアドバンストレイヤー株式会社 照明用ライトガイド保持構造及びホルダー
JP2013099458A (ja) 2011-11-09 2013-05-23 Panasonic Corp レーザ光源装置
US20140200406A1 (en) 2013-01-17 2014-07-17 David B. Bennett Anti-fogging device for endoscope
JP2016120105A (ja) 2014-12-25 2016-07-07 ソニー株式会社 照明装置、照明方法及び観察装置

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JPH05126725A (ja) * 1991-09-25 1993-05-21 Fuji Photo Film Co Ltd 走査型分析顕微鏡
JP3353910B2 (ja) 1992-04-15 2002-12-09 オリンパス光学工業株式会社 硬性内視鏡用対物光学系
JP2006000282A (ja) 2004-06-16 2006-01-05 Olympus Corp 内視鏡の曇り防止装置と内視鏡
JP2007303990A (ja) 2006-05-12 2007-11-22 Matsushita Electric Ind Co Ltd 蛍光診断装置
JP4845590B2 (ja) * 2006-05-22 2011-12-28 オリンパス株式会社 内視鏡システム
JP2009189496A (ja) 2008-02-13 2009-08-27 Olympus Corp 内視鏡装置、内視鏡の観察窓表面に付着した汚れ及び曇りを除去する内視鏡装置の制御方法。
JP5400397B2 (ja) 2009-01-07 2014-01-29 古河電気工業株式会社 バンドルファイバ及び内視鏡システム
JP6103820B2 (ja) * 2012-05-11 2017-03-29 オリンパス株式会社 内視鏡用照明光学系および内視鏡
WO2016006371A1 (ja) 2014-07-09 2016-01-14 オリンパス株式会社 内視鏡システム及び内視鏡用光源装置
KR101619318B1 (ko) 2014-07-09 2016-05-10 한국에너지기술연구원 광 바이어스 장치 및 이를 포함하는 태양전지 분광응답 측정 장치
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CN109068968B (zh) 2016-09-16 2021-02-05 奥林巴斯株式会社 内窥镜用光源装置
CN109758098B (zh) * 2019-01-31 2024-03-19 北京超维景生物科技有限公司 可变焦式腔体内窥镜探测装置及激光扫描腔体内窥镜

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005077436A (ja) 2003-08-29 2005-03-24 Precise Gauges Co Ltd 調芯方法及びその装置、並びに、これを用いた光学モジュールの製造方法及びその装置
JP2010142570A (ja) 2008-12-22 2010-07-01 Hoya Corp 内視鏡光学系
WO2010143402A1 (ja) 2009-06-09 2010-12-16 株式会社フジクラ 光学装置、レーザ照射装置およびレーザ治療装置
WO2012176720A1 (ja) 2011-06-20 2012-12-27 コニカミノルタアドバンストレイヤー株式会社 照明用ライトガイド保持構造及びホルダー
JP2013099458A (ja) 2011-11-09 2013-05-23 Panasonic Corp レーザ光源装置
US20140200406A1 (en) 2013-01-17 2014-07-17 David B. Bennett Anti-fogging device for endoscope
JP2016120105A (ja) 2014-12-25 2016-07-07 ソニー株式会社 照明装置、照明方法及び観察装置

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TW202128073A (zh) 2021-08-01
JP2021048953A (ja) 2021-04-01
DE112020003560T5 (de) 2022-05-05
KR20220031688A (ko) 2022-03-11
WO2021059611A1 (ja) 2021-04-01
CN114303054A (zh) 2022-04-08

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