JP7166280B2 - 発作を抑制する組成物及び方法 - Google Patents

発作を抑制する組成物及び方法 Download PDF

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Publication number
JP7166280B2
JP7166280B2 JP2019554495A JP2019554495A JP7166280B2 JP 7166280 B2 JP7166280 B2 JP 7166280B2 JP 2019554495 A JP2019554495 A JP 2019554495A JP 2019554495 A JP2019554495 A JP 2019554495A JP 7166280 B2 JP7166280 B2 JP 7166280B2
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composition
mice
bacteria
parabacteroides
seizure
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Japanese (ja)
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JP2020502281A5 (cg-RX-API-DMAC7.html
JP2020502281A (ja
Inventor
シャオ,エレイン
ヤノ,ジェシカ
ヴォン,ヘレン
オルソン,クリスティーン
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University of California San Diego UCSD
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University of California San Diego UCSD
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30Dietetic or nutritional methods, e.g. for losing weight
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0216Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • A61K2035/115Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Dairy Products (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2019554495A 2016-12-20 2017-12-20 発作を抑制する組成物及び方法 Active JP7166280B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662436711P 2016-12-20 2016-12-20
US62/436,711 2016-12-20
US201762447992P 2017-01-19 2017-01-19
US62/447,992 2017-01-19
PCT/US2017/067548 WO2018119048A1 (en) 2016-12-20 2017-12-20 Compositions and methods for inhibiting seizures

Publications (3)

Publication Number Publication Date
JP2020502281A JP2020502281A (ja) 2020-01-23
JP2020502281A5 JP2020502281A5 (cg-RX-API-DMAC7.html) 2021-02-04
JP7166280B2 true JP7166280B2 (ja) 2022-11-07

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ID=62627881

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019554495A Active JP7166280B2 (ja) 2016-12-20 2017-12-20 発作を抑制する組成物及び方法

Country Status (7)

Country Link
US (3) US11129858B2 (cg-RX-API-DMAC7.html)
EP (1) EP3558329B1 (cg-RX-API-DMAC7.html)
JP (1) JP7166280B2 (cg-RX-API-DMAC7.html)
CN (2) CN119033822A (cg-RX-API-DMAC7.html)
AU (1) AU2017382197B2 (cg-RX-API-DMAC7.html)
CA (1) CA3047397A1 (cg-RX-API-DMAC7.html)
WO (1) WO2018119048A1 (cg-RX-API-DMAC7.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3558329B1 (en) 2016-12-20 2024-01-31 The Regents of The University of California Compositions and methods for inhibiting seizures
SG11201912105PA (en) * 2017-06-14 2020-01-30 4D Pharma Res Ltd Compositions comprising bacterial strains
WO2020058979A2 (en) * 2018-09-20 2020-03-26 Yeda Research And Development Co. Ltd. Methods of treating amyotrophic lateral sclerosis
WO2020069280A1 (en) * 2018-09-27 2020-04-02 Crestovo Holdings Llc Compositions and methods for treating epilepsy and related disorders
KR102340392B1 (ko) * 2018-10-08 2021-12-17 한국생명공학연구원 우울증의 예방 또는 치료 효과를 가지는 장내 미생물 및 이의 용도
CN110227085A (zh) * 2019-07-16 2019-09-13 江苏省中医院 Akkermansia Muciniphila在制备抗抑郁药物或者保健品中的应用
US20230248782A1 (en) * 2020-06-12 2023-08-10 Morinaga Milk Industry Co., Ltd. Mitochondrial Function-Improving Composition
CN113367328B (zh) * 2021-06-11 2023-02-21 无锡市人民医院 一种调节肠道菌群和能量代谢的多阶段生酮饮食配方
WO2023001368A1 (en) * 2021-07-20 2023-01-26 Université Catholique de Louvain Prevention and/or treatment of reward dysregulation disorders
WO2023001934A1 (en) * 2021-07-20 2023-01-26 Université Catholique de Louvain Prevention and/or treatment of reward dysregulation disorders

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016503418A (ja) 2012-11-19 2016-02-04 ウニベルシテ カソリーク デ ルーベン 代謝障害を処置するアッカーマンシアの使用
US20160143961A1 (en) 2014-11-25 2016-05-26 Epiva Biosciences, Inc. Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6461607B1 (en) 1998-08-24 2002-10-08 Ganeden Biotech, Inc. Probiotic, lactic acid-producing bacteria and uses thereof
CA2940226A1 (en) * 2013-02-22 2014-08-28 The Regents Of The University Of California Compositions and methods for promoting growth of beneficial microbes to treat or prevent disease or prolong life
KR101445243B1 (ko) * 2014-03-28 2014-09-29 서울대학교산학협력단 장내 세균의 군집과 기능의 변화를 이용한 대사성 및 염증성 질환의 조기진단
EP3297727A1 (en) * 2015-05-21 2018-03-28 Yeda Research and Development Co. Ltd Bacterial populations for promoting health
CN114470009A (zh) 2015-05-22 2022-05-13 亚利桑那大学董事会 用于治疗自闭症谱系障碍及相关症状的方法
EP3558329B1 (en) 2016-12-20 2024-01-31 The Regents of The University of California Compositions and methods for inhibiting seizures
US20220184084A1 (en) 2019-03-18 2022-06-16 The Regents Of The University Of California Compositions and methods for treating cushing's disease

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016503418A (ja) 2012-11-19 2016-02-04 ウニベルシテ カソリーク デ ルーベン 代謝障害を処置するアッカーマンシアの使用
US20160143961A1 (en) 2014-11-25 2016-05-26 Epiva Biosciences, Inc. Probiotic and prebiotic compositions, and methods of use thereof for treatment and prevention of graft versus host disease

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Can. J. Infect. Dis. Med. Microbiol., (2016.11), 2016, Article.9032809
J. Mol. Endocrinal., (2017(Epub:2016.12.07)), 58, [1], p.1-14
Mol. Autism, (2016.09), 7, [1], Article.37

Also Published As

Publication number Publication date
EP3558329A1 (en) 2019-10-30
EP3558329C0 (en) 2024-01-31
EP3558329A4 (en) 2020-07-22
CN119033822A (zh) 2024-11-29
WO2018119048A1 (en) 2018-06-28
AU2017382197B2 (en) 2022-12-01
CN110325196A (zh) 2019-10-11
US20200384037A1 (en) 2020-12-10
US20240238350A1 (en) 2024-07-18
CA3047397A1 (en) 2018-06-28
US11883441B2 (en) 2024-01-30
AU2017382197A1 (en) 2019-07-04
EP3558329B1 (en) 2024-01-31
US20220184144A1 (en) 2022-06-16
CN110325196B (zh) 2024-08-27
JP2020502281A (ja) 2020-01-23
US12364717B2 (en) 2025-07-22
US11129858B2 (en) 2021-09-28

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