JP7146286B2 - 多発性硬化症の進行を検出する、サブタイプ分類する、および/または評価するための、診断用バイオマーカー - Google Patents

多発性硬化症の進行を検出する、サブタイプ分類する、および/または評価するための、診断用バイオマーカー Download PDF

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JP7146286B2
JP7146286B2 JP2019562415A JP2019562415A JP7146286B2 JP 7146286 B2 JP7146286 B2 JP 7146286B2 JP 2019562415 A JP2019562415 A JP 2019562415A JP 2019562415 A JP2019562415 A JP 2019562415A JP 7146286 B2 JP7146286 B2 JP 7146286B2
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ロバート ジー. ナーゲル
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ローワン・ユニバーシティ
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552Glass or silica
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/285Demyelinating diseases; Multipel sclerosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
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  • Hematology (AREA)
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  • General Physics & Mathematics (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
JP2019562415A 2017-05-10 2018-05-10 多発性硬化症の進行を検出する、サブタイプ分類する、および/または評価するための、診断用バイオマーカー Active JP7146286B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762504130P 2017-05-10 2017-05-10
US62/504,130 2017-05-10
PCT/US2018/032130 WO2018209126A1 (en) 2017-05-10 2018-05-10 Diagnostic biomarkers for detecting, subtyping, and/or assessing progression of multiple sclerosis

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JP2020519895A JP2020519895A (ja) 2020-07-02
JP2020519895A5 JP2020519895A5 (https=) 2021-07-26
JP7146286B2 true JP7146286B2 (ja) 2022-10-04

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US (3) US20210003570A1 (https=)
EP (1) EP3622291A4 (https=)
JP (1) JP7146286B2 (https=)
CA (1) CA3062763A1 (https=)
WO (1) WO2018209126A1 (https=)

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CN110186962B (zh) * 2019-05-10 2021-06-25 天津大学 一种用于电容层析成像的不完整测量数据成像方法
BR112023001788A2 (pt) * 2020-08-03 2023-02-23 Prevail Therapeutics Inc Vetores aav que codificam parkina e usos da mesma

Citations (1)

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Publication number Priority date Publication date Assignee Title
JP2013528799A (ja) 2010-05-13 2013-07-11 ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー 神経変性疾患の検知および診断のための診断用自己抗体プロファイル

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WO2018209126A1 (en) 2018-11-15
US20220390447A1 (en) 2022-12-08
US12174187B2 (en) 2024-12-24
US20220390448A1 (en) 2022-12-08
EP3622291A1 (en) 2020-03-18
JP2020519895A (ja) 2020-07-02
CA3062763A1 (en) 2018-11-15
US20210003570A1 (en) 2021-01-07
EP3622291A4 (en) 2021-04-21

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