JP7123058B2 - 皮膚疾患の処置のための併用療法 - Google Patents

皮膚疾患の処置のための併用療法 Download PDF

Info

Publication number
JP7123058B2
JP7123058B2 JP2019537351A JP2019537351A JP7123058B2 JP 7123058 B2 JP7123058 B2 JP 7123058B2 JP 2019537351 A JP2019537351 A JP 2019537351A JP 2019537351 A JP2019537351 A JP 2019537351A JP 7123058 B2 JP7123058 B2 JP 7123058B2
Authority
JP
Japan
Prior art keywords
substituted
unsubstituted
composition
administration
diindolylmethane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019537351A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020506169A (ja
JP2020506169A5 (enExample
Inventor
スカイフ,マイケル,シー.
Original Assignee
スキンテック ライフ サイエンス リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by スキンテック ライフ サイエンス リミテッド filed Critical スキンテック ライフ サイエンス リミテッド
Publication of JP2020506169A publication Critical patent/JP2020506169A/ja
Publication of JP2020506169A5 publication Critical patent/JP2020506169A5/ja
Priority to JP2022127265A priority Critical patent/JP7481402B2/ja
Application granted granted Critical
Publication of JP7123058B2 publication Critical patent/JP7123058B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203Retinoic acids ; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019537351A 2017-01-20 2018-01-19 皮膚疾患の処置のための併用療法 Active JP7123058B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022127265A JP7481402B2 (ja) 2017-01-20 2022-08-09 皮膚疾患の処置のための併用療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762448808P 2017-01-20 2017-01-20
US62/448,808 2017-01-20
PCT/IB2018/000109 WO2018134683A1 (en) 2017-01-20 2018-01-19 Combination therapy for treatment of skin diseases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022127265A Division JP7481402B2 (ja) 2017-01-20 2022-08-09 皮膚疾患の処置のための併用療法

Publications (3)

Publication Number Publication Date
JP2020506169A JP2020506169A (ja) 2020-02-27
JP2020506169A5 JP2020506169A5 (enExample) 2021-03-04
JP7123058B2 true JP7123058B2 (ja) 2022-08-22

Family

ID=61731720

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019537351A Active JP7123058B2 (ja) 2017-01-20 2018-01-19 皮膚疾患の処置のための併用療法
JP2022127265A Active JP7481402B2 (ja) 2017-01-20 2022-08-09 皮膚疾患の処置のための併用療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022127265A Active JP7481402B2 (ja) 2017-01-20 2022-08-09 皮膚疾患の処置のための併用療法

Country Status (8)

Country Link
US (2) US11241467B2 (enExample)
EP (1) EP3570889A1 (enExample)
JP (2) JP7123058B2 (enExample)
CN (2) CN116036290A (enExample)
AU (1) AU2018209393B2 (enExample)
BR (1) BR112019014942A2 (enExample)
CA (1) CA3050208A1 (enExample)
WO (1) WO2018134683A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018051183A1 (en) * 2016-09-15 2018-03-22 Skintech Life Science Limited Sublingual or buccal administration of dim for treatment of skin diseases
AU2018209393B2 (en) 2017-01-20 2024-02-15 Skintech Life Science Limited Combination therapy for treatment of skin diseases
WO2025097063A1 (en) * 2023-11-01 2025-05-08 Skintech Life Science Limited Topical dim compositions and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014508793A (ja) 2011-03-25 2014-04-10 アイアイエーエー リミテッド ジインドリルメタン及びレチノイドを含む皮膚症状を治療するための組成物
WO2014177123A1 (de) 2013-04-30 2014-11-06 Melnik Bodo C Akne-medikament und verfahren zu seiner herstellung

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665367A (en) * 1996-09-27 1997-09-09 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin care compositions containing naringenin and/or quercetin and a retinoid
US6599913B1 (en) * 2001-06-29 2003-07-29 Schering Corporation Treating allergic and inflammatory conditions
US6767563B2 (en) * 2001-10-30 2004-07-27 Michael D. Farley Immune functions
US20030166583A1 (en) * 2002-02-22 2003-09-04 Oliver Yoa-Pu Hu Dermal cytochrome P450 1A inhibitors and enhancers
WO2008057253A2 (en) * 2006-10-27 2008-05-15 Bioresponse, L.L.C. Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles
FR2908604B1 (fr) * 2006-11-16 2013-06-28 Physcience Complement alimentaire pour la prevention ou la lutte contre la chute des cheveux, l'acne, l'hirsutisme et la secretion sudorale apocrine excessive.
RU2419426C1 (ru) * 2010-04-26 2011-05-27 Всеволод Иванович Киселев Лекарственное средство на основе дииндолилметана (dim) с повышенной биодоступностью и его использование в лечении гиперпластических и воспалительных заболеваний человека
MX2013011835A (es) * 2011-04-12 2013-11-01 Nestec Sa Composiciones nutricionales que incluyen acidos grasos de cadena ramificada para la curacion de heridas.
US20160051536A1 (en) * 2013-04-08 2016-02-25 Virginia Commonwealth University Compositions to alleviate presystemic metabolism of opioids
GB2528482A (en) * 2014-07-23 2016-01-27 Skintech Life Science Ltd Pharmaceutical agent
WO2018051183A1 (en) * 2016-09-15 2018-03-22 Skintech Life Science Limited Sublingual or buccal administration of dim for treatment of skin diseases
AU2018209393B2 (en) 2017-01-20 2024-02-15 Skintech Life Science Limited Combination therapy for treatment of skin diseases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014508793A (ja) 2011-03-25 2014-04-10 アイアイエーエー リミテッド ジインドリルメタン及びレチノイドを含む皮膚症状を治療するための組成物
WO2014177123A1 (de) 2013-04-30 2014-11-06 Melnik Bodo C Akne-medikament und verfahren zu seiner herstellung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS,1985年,Vol.240, No.1,pp.345-357

Also Published As

Publication number Publication date
AU2018209393A1 (en) 2019-08-08
CA3050208A1 (en) 2018-07-26
JP7481402B2 (ja) 2024-05-10
US20220193167A1 (en) 2022-06-23
US11241467B2 (en) 2022-02-08
RU2019124938A (ru) 2021-02-20
US20200138884A1 (en) 2020-05-07
BR112019014942A2 (pt) 2020-04-14
AU2018209393B2 (en) 2024-02-15
WO2018134683A1 (en) 2018-07-26
JP2022169626A (ja) 2022-11-09
RU2019124938A3 (enExample) 2021-05-27
JP2020506169A (ja) 2020-02-27
EP3570889A1 (en) 2019-11-27
CN116036290A (zh) 2023-05-02
CN110446505A (zh) 2019-11-12

Similar Documents

Publication Publication Date Title
JP7481402B2 (ja) 皮膚疾患の処置のための併用療法
TW201615221A (zh) 炎症用藥臨床新應用
US20240390326A1 (en) Sublingual or buccal administration of dim for treatment of skin diseases
WO2025113347A1 (zh) 包含维甲酸的药物组合物在制备治疗肝细胞癌伴腹腔转移的药物中的用途
RU2775974C2 (ru) Комбинированная терапия для лечения кожных заболеваний
JP6283054B2 (ja) 生体内のメイラード反応抑制剤またはAGEs生成抑制剤
HK40011827A (en) Combination therapy for treatment of skin diseases
JP2009539941A (ja) Slv308およびl−dopaを含んでなる組み合わせ製剤
FR2823211A1 (fr) Composition a base d'un polyphosphate de s-adenosyl-l-methionine et utilisations d'un tel polyphosphate
JP2010077102A (ja) 高齢者向け機能食品および医薬組成物
JP2012193174A (ja) トラネキサム酸を含有する生体内のメイラード反応抑制剤組成物
CN110996937A (zh) 包含dgla的药物组合物及其用途
TWI735658B (zh) 用於減少代謝症候群之組合物及其應用
HK40008900A (en) Sublingual or buccal administration of dim for treatment of skin diseases
WO2024173775A1 (en) Dietary supplement for managing stress-induced inflammatory skin disorders
EP4665168A1 (en) Dietary supplement for managing stress-induced inflammatory skin disorders
JP6027752B2 (ja) AGEs生成抑制剤
TW201028177A (en) Hydrogel composition for the treatment of dermatological disorders

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20191113

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210119

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20210119

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20211220

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220322

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20220713

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20220809

R150 Certificate of patent or registration of utility model

Ref document number: 7123058

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150