AU2018209393B2 - Combination therapy for treatment of skin diseases - Google Patents

Combination therapy for treatment of skin diseases Download PDF

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Publication number
AU2018209393B2
AU2018209393B2 AU2018209393A AU2018209393A AU2018209393B2 AU 2018209393 B2 AU2018209393 B2 AU 2018209393B2 AU 2018209393 A AU2018209393 A AU 2018209393A AU 2018209393 A AU2018209393 A AU 2018209393A AU 2018209393 B2 AU2018209393 B2 AU 2018209393B2
Authority
AU
Australia
Prior art keywords
substituted
composition
unsubstituted diindolylmethane
administration
diindolylmethane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2018209393A
Other languages
English (en)
Other versions
AU2018209393A1 (en
Inventor
Michael C. Scaife
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Skintech Life Science Ltd
Original Assignee
Skintech Life Science Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Skintech Life Science Ltd filed Critical Skintech Life Science Ltd
Publication of AU2018209393A1 publication Critical patent/AU2018209393A1/en
Application granted granted Critical
Publication of AU2018209393B2 publication Critical patent/AU2018209393B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2018209393A 2017-01-20 2018-01-19 Combination therapy for treatment of skin diseases Ceased AU2018209393B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762448808P 2017-01-20 2017-01-20
US62/448,808 2017-01-20
PCT/IB2018/000109 WO2018134683A1 (en) 2017-01-20 2018-01-19 Combination therapy for treatment of skin diseases

Publications (2)

Publication Number Publication Date
AU2018209393A1 AU2018209393A1 (en) 2019-08-08
AU2018209393B2 true AU2018209393B2 (en) 2024-02-15

Family

ID=61731720

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018209393A Ceased AU2018209393B2 (en) 2017-01-20 2018-01-19 Combination therapy for treatment of skin diseases

Country Status (8)

Country Link
US (2) US11241467B2 (enExample)
EP (1) EP3570889A1 (enExample)
JP (2) JP7123058B2 (enExample)
CN (2) CN110446505A (enExample)
AU (1) AU2018209393B2 (enExample)
BR (1) BR112019014942A2 (enExample)
CA (1) CA3050208A1 (enExample)
WO (1) WO2018134683A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11331303B2 (en) * 2016-09-15 2022-05-17 Skintech Life Science Limited Sublingual or buccal administration of dim for treatment of skin diseases
US11241467B2 (en) 2017-01-20 2022-02-08 Skintech Life Science Limited Composition for treating acne
WO2025097063A1 (en) * 2023-11-01 2025-05-08 Skintech Life Science Limited Topical dim compositions and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030166583A1 (en) * 2002-02-22 2003-09-04 Oliver Yoa-Pu Hu Dermal cytochrome P450 1A inhibitors and enhancers
WO2012130698A1 (en) * 2011-03-25 2012-10-04 Iiaa Limited Composition comprising a diindolylmethane and a retinoid to treat a skin condition
WO2014177123A1 (de) * 2013-04-30 2014-11-06 Melnik Bodo C Akne-medikament und verfahren zu seiner herstellung
US20160101083A1 (en) * 2006-10-27 2016-04-14 Bioresponse, L.L.C. Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665367A (en) * 1996-09-27 1997-09-09 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin care compositions containing naringenin and/or quercetin and a retinoid
US6599913B1 (en) * 2001-06-29 2003-07-29 Schering Corporation Treating allergic and inflammatory conditions
US6767563B2 (en) * 2001-10-30 2004-07-27 Michael D. Farley Immune functions
FR2908604B1 (fr) * 2006-11-16 2013-06-28 Physcience Complement alimentaire pour la prevention ou la lutte contre la chute des cheveux, l'acne, l'hirsutisme et la secretion sudorale apocrine excessive.
RU2419426C1 (ru) * 2010-04-26 2011-05-27 Всеволод Иванович Киселев Лекарственное средство на основе дииндолилметана (dim) с повышенной биодоступностью и его использование в лечении гиперпластических и воспалительных заболеваний человека
WO2012140118A1 (en) * 2011-04-12 2012-10-18 Nestec S.A. Nutritional compositions including branched chain fatty acids for wound healing
BR112015025684A2 (pt) * 2013-04-08 2017-07-18 Indivior Uk Ltd método para proporcionar um ou mais opióide(s) a um indivíduo, forma de dosagem, método para tratar ou prevenir dor e método para tratar ou prevenir dependência ou vício
GB2528482A (en) * 2014-07-23 2016-01-27 Skintech Life Science Ltd Pharmaceutical agent
US11331303B2 (en) * 2016-09-15 2022-05-17 Skintech Life Science Limited Sublingual or buccal administration of dim for treatment of skin diseases
US11241467B2 (en) 2017-01-20 2022-02-08 Skintech Life Science Limited Composition for treating acne

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030166583A1 (en) * 2002-02-22 2003-09-04 Oliver Yoa-Pu Hu Dermal cytochrome P450 1A inhibitors and enhancers
US20160101083A1 (en) * 2006-10-27 2016-04-14 Bioresponse, L.L.C. Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles
WO2012130698A1 (en) * 2011-03-25 2012-10-04 Iiaa Limited Composition comprising a diindolylmethane and a retinoid to treat a skin condition
WO2014177123A1 (de) * 2013-04-30 2014-11-06 Melnik Bodo C Akne-medikament und verfahren zu seiner herstellung

Also Published As

Publication number Publication date
US11241467B2 (en) 2022-02-08
CN110446505A (zh) 2019-11-12
EP3570889A1 (en) 2019-11-27
RU2019124938A3 (enExample) 2021-05-27
CN116036290A (zh) 2023-05-02
US20220193167A1 (en) 2022-06-23
AU2018209393A1 (en) 2019-08-08
JP2020506169A (ja) 2020-02-27
RU2019124938A (ru) 2021-02-20
US20200138884A1 (en) 2020-05-07
CA3050208A1 (en) 2018-07-26
JP2022169626A (ja) 2022-11-09
WO2018134683A1 (en) 2018-07-26
JP7123058B2 (ja) 2022-08-22
BR112019014942A2 (pt) 2020-04-14
JP7481402B2 (ja) 2024-05-10

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired