JP7109160B2 - 神経外傷性障害において第ｘｉｉ因子インヒビターを使用する療法 - Google Patents

神経外傷性障害において第ｘｉｉ因子インヒビターを使用する療法 Download PDF

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JP7109160B2
JP7109160B2 JP2016573808A JP2016573808A JP7109160B2 JP 7109160 B2 JP7109160 B2 JP 7109160B2 JP 2016573808 A JP2016573808 A JP 2016573808A JP 2016573808 A JP2016573808 A JP 2016573808A JP 7109160 B2 JP7109160 B2 JP 7109160B2
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クリストフ・クラインシュニッツ
マルク・ノルテ
アンナ－レーナ・ジレン
クリスティアーネ・アルベルト－ヴァイセンベルガー
ザーラ・ホップ－クレーマー
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ツェー・エス・エル・ベーリング・ゲー・エム・ベー・ハー
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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JP2016573808A 2014-06-18 2015-06-18 神経外傷性障害において第ｘｉｉ因子インヒビターを使用する療法 Active JP7109160B2 (ja)

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EP14172910.3 2014-06-18
EP14172910 2014-06-18
PCT/EP2015/063760 WO2015193457A1 (en) 2014-06-18 2015-06-18 Therapy using a factor xii inhibitor in a neurotraumatic disorder

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JP2017524675A JP2017524675A (ja) 2017-08-31
JP2017524675A5 JP2017524675A5 (enExample) 2018-07-19
JP7109160B2 true JP7109160B2 (ja) 2022-07-29

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US (2) US20170114119A1 (enExample)
EP (1) EP3157548B1 (enExample)
JP (1) JP7109160B2 (enExample)
KR (1) KR102513050B1 (enExample)
CN (1) CN106456778A (enExample)
AU (1) AU2015276089B2 (enExample)
BR (1) BR112016029624A2 (enExample)
CA (1) CA2950988C (enExample)
DK (1) DK3157548T3 (enExample)
ES (1) ES2886859T3 (enExample)
PL (1) PL3157548T3 (enExample)
WO (1) WO2015193457A1 (enExample)

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CN106456778A (zh) 2014-06-18 2017-02-22 德国杰特贝林生物制品有限公司 在神经创伤性病患中使用因子xii抑制剂进行治疗
CN108883104A (zh) * 2016-03-30 2018-11-23 森泰克希斯公司 用于在治疗成熟脑损伤中使用的mGluR5的负性变构调节剂
CA3019851A1 (en) * 2016-04-06 2017-10-12 Csl Limited Method of treating atherosclerosis
CN111479587B (zh) 2017-12-15 2024-01-09 杰特有限公司 FXIIa抑制剂在治疗肾纤维化和/或慢性肾脏疾病中的应用
US12134657B2 (en) * 2018-11-28 2024-11-05 Oregon Health & Science University Therapeutic factor XII antibody
EP4333901A4 (en) * 2021-05-03 2025-07-09 Harvard College FC FUSION PROTEIN-BASED THERAPEUTIC AGENT FOR THE TREATMENT OF PANCREATITIS

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ＣＡＮＣＥＲ ＲＥＳＥＡＲＣＨ， １９８１， Ｖｏｌ．４１， ｐｐ．２１０３－２１０８，検索日：２０２２年１月２８日、＜ｈｔｔｐｓ：／／ｃａｎｃｅｒｒｅｓ．ａａｃｒｊｏｕｒｎａｌｓ．ｏｒｇ／ｃｏｎｔｅｎｔ／ｃａｎｒｅｓ／４１／６／２１０３．ｆｕｌｌ．ｐｄｆ＞
Ｃｉｒｃｕｌａｔｉｏｎ，２０１０年，Ｖｏｌ．１２１，Ｎｏ．１３，ｐ１５１０－１５１７
ＭＳＤ マニュアル プロフェッショナル版 外傷性脳損傷（ＴＢＩ）、最終査読／改訂年月 ２０１７年 １１月、検索日：２０２１年６月１７日、＜ＵＲＬ： ｈｔｔｐｓ：／／ｗｗｗ．ｍｓｄｍａｎｕａｌｓ．ｃｏｍ／ｊａ－ｊｐ／％Ｅ３％８３％９７％Ｅ３％８３％ＡＤ％Ｅ３％８３％９５％Ｅ３％８２％Ａ７％Ｅ３％８３％８３％Ｅ３％８２％Ｂ７％Ｅ３％８３％Ａ７％Ｅ３％８３％８Ａ％Ｅ３％８３％ＡＢ／２２－％Ｅ５％Ａ４％９６％Ｅ５％８２％Ｂ７％Ｅ３％８１％Ａ８％Ｅ４％Ｂ８％ＡＤ％Ｅ６％ＡＦ％９２／％Ｅ５％Ａ４％９６％Ｅ５％８２％Ｂ７％Ｅ６％８０％Ａ７％Ｅ８％８４％Ｂ３％Ｅ６％９０％８Ｄ％Ｅ５％８２％Ｂ７－％ＥＦ％ＢＣ％８８ｔｂｉ％ＥＦ％ＢＣ％８９／％Ｅ５％Ａ４％９６％Ｅ５％８２％Ｂ７％Ｅ６％８０％Ａ７％Ｅ８％８４％Ｂ３％Ｅ６％９０％８Ｄ％Ｅ５％８２％Ｂ７％ＥＦ％ＢＣ％８８ｔｂｉ％ＥＦ％ＢＣ％８９＞
ＮＣＢＩ Ｃ１Ｓ ｃｏｍｐｌｅｍｅｎｔ Ｃ１ｓ［Ｈｏｍｏ ｓａｐｉｅｎｓ（ｈｕｍａｎ）］、検索日：２０２２年１月２８日、＜ｈｔｔｐｓ：／／ｗｗｗ．ｎｃｂｉ．ｎｌｍ．ｎｉｈ．ｇｏｖ／ｇｅｎｅ／７１６＞
Ｐｒｏｇｒｅｓｓ ｉｎ Ｎｅｕｒｏｂｉｏｌｏｇｙ，２０１３年，Ｖｏｌ．１０１－１０２，ｐ６５－８２
血栓止血誌 ２０１４， Ｖｏｌ．２５， Ｎｏ．１， ｐｐ．２３－３２、検索日：２０２２年１月２８日、＜ｈｔｔｐｓ：／／ｗｗｗ．ｊｓｔａｇｅ．ｊｓｔ．ｇｏ．ｊｐ／ａｒｔｉｃｌｅ／ｊｊｓｔｈ／２５／１／２５＿２３／＿ｐｄｆ／－ｃｈａｒ／ｊａ＞
血栓止血誌， ２０１４， Ｖｏｌ．２５， Ｎｏ．３， ｐｐ．４１１－４２２，検索日：２０２１年６月１７日、＜ＵＲＬ： ｈｔｔｐｓ：／／ｗｗｗ．ｊｓｔｈ．ｏｒｇ／ｐｕｂｌｉｃａｔｉｏｎｓ／ｐｄｆ／ｊｓｔａｇｅ／％Ｅ７％９９％ＢＡ％Ｅ７％８Ｆ％ＢＥ％Ｅ６％Ａ９％９Ｆ％Ｅ６％Ａ７％８Ｂ２５－３．ｐｄｆ＞

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ES2886859T3 (es) 2021-12-21
PL3157548T3 (pl) 2022-01-17
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US12065481B2 (en) 2024-08-20
KR20170016503A (ko) 2017-02-13
CN106456778A (zh) 2017-02-22
KR102513050B1 (ko) 2023-03-29
JP2017524675A (ja) 2017-08-31
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US20170114119A1 (en) 2017-04-27
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