KR102513050B1 - 신경외상성 장애에서의 인자 xii 억제제를 이용한 치료요법 - Google Patents
신경외상성 장애에서의 인자 xii 억제제를 이용한 치료요법 Download PDFInfo
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- KR102513050B1 KR102513050B1 KR1020177001620A KR20177001620A KR102513050B1 KR 102513050 B1 KR102513050 B1 KR 102513050B1 KR 1020177001620 A KR1020177001620 A KR 1020177001620A KR 20177001620 A KR20177001620 A KR 20177001620A KR 102513050 B1 KR102513050 B1 KR 102513050B1
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| JP2019515892A (ja) * | 2016-03-30 | 2019-06-13 | シンタクシス・エービー | 成熟脳損傷の治療における使用のためのmGluR5のネガティブアロステリックモジュレーター |
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| US12134657B2 (en) * | 2018-11-28 | 2024-11-05 | Oregon Health & Science University | Therapeutic factor XII antibody |
| US20240228585A1 (en) * | 2021-05-03 | 2024-07-11 | President And Fellows Of Harvard College | Fc-fusion protein therapeutic for the treatment of pancreatitis |
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| DE3572982D1 (en) | 1984-03-06 | 1989-10-19 | Takeda Chemical Industries Ltd | Chemically modified lymphokine and production thereof |
| US4963657A (en) | 1988-06-09 | 1990-10-16 | Temple University Of The Commonwealth System Of Higher Education | Monoclonal antibodies to the light chain region of human factor XII and methods of preparing and using the same |
| CA2006596C (en) | 1988-12-22 | 2000-09-05 | Rika Ishikawa | Chemically-modified g-csf |
| GB8901859D0 (en) | 1989-01-27 | 1989-03-15 | Shield Diagnostics Limited | Diagnostic test |
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| US5252714A (en) | 1990-11-28 | 1993-10-12 | The University Of Alabama In Huntsville | Preparation and use of polyethylene glycol propionaldehyde |
| ATE240740T1 (de) | 1991-03-15 | 2003-06-15 | Amgen Inc | Pegylation von polypeptiden |
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| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
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| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
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| CA2678001C (en) | 2007-02-12 | 2017-07-11 | Stefan Schulte | Therapeutic application of kazal-type serine protease inhibitors |
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| US20120156230A1 (en) | 2010-12-17 | 2012-06-21 | Abbot Stewart | Treatment of spinal cord injury and traumatic brain injury using placental stem cells |
| EP2497489A1 (en) | 2011-03-09 | 2012-09-12 | CSL Behring GmbH | Factor XII inhibitors for the treatment of silent brain ischemia and ischemia of other organs |
| PL2683397T3 (pl) | 2011-03-09 | 2018-01-31 | Csl Behring Gmbh | Inhibitory czynnika XII do podawania w zabiegach medycznych obejmujących kontakt z powierzchniami sztucznymi |
| EP2548892A1 (en) | 2011-07-22 | 2013-01-23 | CSL Behring GmbH | Inhibitory anti-Factor XII/XIIa monoclonal Antibodies and their uses |
| IL230564B2 (en) | 2011-07-22 | 2023-09-01 | Csl Ltd | Anticoagulant monoclonal antibodies anti–factor xii/fxiia, a method for their preparation, a pharmaceutical compound containing them and medical uses. |
| EP2758076B1 (en) | 2011-09-24 | 2018-12-12 | CSL Behring GmbH | Combination therapy using immunoglobulin and c1-inhibitor |
| EP2623110A1 (en) | 2012-01-31 | 2013-08-07 | CSL Behring GmbH | Factor XII inhibitors for the treatment of neurological inflammatory disorders |
| US10286047B2 (en) | 2013-03-08 | 2019-05-14 | Csl Behring Gmbh | Treatment and prevention of remote ischemia-reperfusion injury |
| KR20160026905A (ko) | 2013-06-28 | 2016-03-09 | 체에스엘 베링 게엠베하 | 인자 xii 억제제 및 c1-억제제를 이용한 병용 치료요법 |
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| DK3157548T3 (da) | 2014-06-18 | 2021-09-06 | Csl Behring Gmbh | Terapi anvendelse af en faktor xii-inhibitor i en neurotraumatisk sygdom |
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- 2015-06-18 JP JP2016573808A patent/JP7109160B2/ja active Active
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2019
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Non-Patent Citations (2)
| Title |
|---|
| Hagedorn 등, Circulation. 2010, 121, 1510~1517* |
| Progress in Neurobiology. 101~102 (2013) 65~82* |
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| CA2950988C (en) | 2024-02-06 |
| JP7109160B2 (ja) | 2022-07-29 |
| AU2015276089B2 (en) | 2021-03-18 |
| PL3157548T3 (pl) | 2022-01-17 |
| AU2015276089A1 (en) | 2017-02-02 |
| ES2886859T3 (es) | 2021-12-21 |
| EP3157548A1 (en) | 2017-04-26 |
| CA2950988A1 (en) | 2015-12-23 |
| BR112016029624A2 (pt) | 2017-10-24 |
| EP3157548B1 (en) | 2021-08-04 |
| US20200131248A1 (en) | 2020-04-30 |
| JP2017524675A (ja) | 2017-08-31 |
| US20170114119A1 (en) | 2017-04-27 |
| US12065481B2 (en) | 2024-08-20 |
| DK3157548T3 (da) | 2021-09-06 |
| WO2015193457A1 (en) | 2015-12-23 |
| KR20170016503A (ko) | 2017-02-13 |
| CN106456778A (zh) | 2017-02-22 |
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