JP7105783B2 - 組換え宿主におけるシトロネラール及びシトロネロールの生産 - Google Patents
組換え宿主におけるシトロネラール及びシトロネロールの生産 Download PDFInfo
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- JP7105783B2 JP7105783B2 JP2019540704A JP2019540704A JP7105783B2 JP 7105783 B2 JP7105783 B2 JP 7105783B2 JP 2019540704 A JP2019540704 A JP 2019540704A JP 2019540704 A JP2019540704 A JP 2019540704A JP 7105783 B2 JP7105783 B2 JP 7105783B2
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- polypeptide
- citronellal
- citronellol
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- C12N9/0004—Oxidoreductases (1.)
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- C12N15/09—Recombinant DNA-technology
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- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
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- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
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- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
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- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
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- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
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- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01021—Aldehyde reductase (1.1.1.21), i.e. aldose-reductase
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- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01183—Geraniol dehydrogenase (1.1.1.183)
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- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/99—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with other acceptors (1.2.99)
- C12Y102/99006—Carboxylate reductase (1.2.99.6)
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- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
- C12Y103/01031—2-Enoate reductase (1.3.1.31)
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- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
- C12Y205/01001—Dimethylallyltranstransferase (2.5.1.1)
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- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/07—Diphosphoric monoester hydrolases (3.1.7)
- C12Y301/07011—Geranyl diphosphate diphosphatase (3.1.7.11)
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- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662406906P | 2016-10-11 | 2016-10-11 | |
| US62/406,906 | 2016-10-11 | ||
| PCT/EP2017/075995 WO2018069418A2 (en) | 2016-10-11 | 2017-10-11 | Production of citronellal and citronellol in recombinant hosts |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019530478A JP2019530478A (ja) | 2019-10-24 |
| JP2019530478A5 JP2019530478A5 (https=) | 2020-11-19 |
| JP7105783B2 true JP7105783B2 (ja) | 2022-07-25 |
Family
ID=60702584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019540704A Active JP7105783B2 (ja) | 2016-10-11 | 2017-10-11 | 組換え宿主におけるシトロネラール及びシトロネロールの生産 |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US11299717B2 (https=) |
| JP (1) | JP7105783B2 (https=) |
| WO (1) | WO2018069418A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108732289B (zh) * | 2018-08-14 | 2020-10-09 | 东莞波顿香料有限公司 | 鉴别天然香茅醇和合成香茅醇的方法 |
| CN109810999B (zh) * | 2019-03-11 | 2023-03-24 | 湖北工业大学 | 一种利用微生物发酵生产橙花醇的方法 |
| CN110438145A (zh) * | 2019-07-15 | 2019-11-12 | 天津大学 | 合成香叶醇的谷氨酸棒状杆菌及构建方法及应用 |
| CN112680483B (zh) * | 2020-12-25 | 2022-09-16 | 中国林业科学研究院亚热带林业研究所 | 山鸡椒醇脱氢酶LcADH31在制备柠檬醛或以其为活性物质的产品中的应用 |
| CN113337450B (zh) * | 2021-04-25 | 2023-03-31 | 华东理工大学 | 一种大肠杆菌基因工程菌、构建方法以及全细胞催化生产(r)-香茅醛的方法 |
| CN113215131B (zh) * | 2021-06-04 | 2023-06-20 | 天津大学佐治亚理工深圳学院 | 磷酸水解酶及其应用 |
| CN113930457B (zh) * | 2021-09-28 | 2024-05-03 | 浙江工业大学 | 一种双酶偶联合成(s)-香茅醇的方法 |
| EP4460569A1 (en) * | 2022-01-07 | 2024-11-13 | Ginkgo Bioworks, Inc. | Skin commensal bacteria engineered to produce terpenes |
| CN114806911B (zh) * | 2022-04-02 | 2023-10-03 | 天津科技大学 | 一种利用解脂耶氏酵母线粒体途径定位合成α-红没药烯的方法 |
| CN115927487A (zh) * | 2022-12-29 | 2023-04-07 | 中国林业科学研究院亚热带林业研究所 | 山鸡椒醇脱氢酶基因簇LcADHs在制备柠檬醛或以其为活性物质的产品中的应用 |
| CN117126755B (zh) * | 2023-10-24 | 2024-03-12 | 深圳先进技术研究院 | 一种葡萄糖-乙醇共碳源发酵高产香叶醇的酿酒酵母工程菌及其构建方法和应用 |
| CN120700011A (zh) * | 2025-07-04 | 2025-09-26 | 浙江大学 | 合成单萜的基因工程菌及其构建方法与应用 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101186924A (zh) | 2007-11-30 | 2008-05-28 | 华东理工大学 | 用于催化柠檬醛生成香茅醛的基因工程菌及其构建方法 |
| US20100112671A1 (en) | 2001-12-06 | 2010-05-06 | Keasling Jay D | Host Cells for Production of Isoprenoid Compounds |
| WO2014027118A1 (en) | 2012-08-17 | 2014-02-20 | Evolva Sa | Increased production of terpenes and terpenoids |
| WO2016008883A1 (en) | 2014-07-14 | 2016-01-21 | Photanol B.V. | Biosynthesis of monoterpenes in cyanobacteria |
| WO2016108236A1 (en) | 2014-12-29 | 2016-07-07 | Futuragene Israel Ltd. | Nucleic acid constructs, plants comprising same and uses thereof in enhancing plant pest resistance and altering plant monoterpene profile |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060014264A1 (en) | 2004-07-13 | 2006-01-19 | Stowers Institute For Medical Research | Cre/lox system with lox sites having an extended spacer region |
| WO2009140394A1 (en) | 2008-05-13 | 2009-11-19 | Cargill, Incorporated | Separation of rebaudioside a from stevia glycosides using chromatography |
-
2017
- 2017-10-11 WO PCT/EP2017/075995 patent/WO2018069418A2/en not_active Ceased
- 2017-10-11 US US16/338,186 patent/US11299717B2/en active Active
- 2017-10-11 JP JP2019540704A patent/JP7105783B2/ja active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100112671A1 (en) | 2001-12-06 | 2010-05-06 | Keasling Jay D | Host Cells for Production of Isoprenoid Compounds |
| CN101186924A (zh) | 2007-11-30 | 2008-05-28 | 华东理工大学 | 用于催化柠檬醛生成香茅醛的基因工程菌及其构建方法 |
| WO2014027118A1 (en) | 2012-08-17 | 2014-02-20 | Evolva Sa | Increased production of terpenes and terpenoids |
| WO2016008883A1 (en) | 2014-07-14 | 2016-01-21 | Photanol B.V. | Biosynthesis of monoterpenes in cyanobacteria |
| WO2016108236A1 (en) | 2014-12-29 | 2016-07-07 | Futuragene Israel Ltd. | Nucleic acid constructs, plants comprising same and uses thereof in enhancing plant pest resistance and altering plant monoterpene profile |
Non-Patent Citations (3)
| Title |
|---|
| PARDO E. et al.,Microb Cell Fact,2015年,14:136 |
| STEYER D. et al.,Food Microbiology,2013年,33,p.228-234 |
| ZEBEC Z. et al.,Current Opinion in Chemical Biology,2016年06月14日,34,p.37-43 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019530478A (ja) | 2019-10-24 |
| WO2018069418A2 (en) | 2018-04-19 |
| WO2018069418A3 (en) | 2018-05-24 |
| US11299717B2 (en) | 2022-04-12 |
| US20190225945A1 (en) | 2019-07-25 |
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