JP7094941B2 - Ｆｃｒｎ抗体及びその使用方法 - Google Patents

Ｆｃｒｎ抗体及びその使用方法 Download PDF

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JP7094941B2
JP7094941B2 JP2019504902A JP2019504902A JP7094941B2 JP 7094941 B2 JP7094941 B2 JP 7094941B2 JP 2019504902 A JP2019504902 A JP 2019504902A JP 2019504902 A JP2019504902 A JP 2019504902A JP 7094941 B2 JP7094941 B2 JP 7094941B2
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sequence
cdr
antibody
amino acid
seq
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JP2019526540A5 (enExample
JP2019526540A (ja
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レオナ イー． リング
スチャリタ ロイ
ナサニエル ワッシュバーン
マリリン ケーリー
デビット ジェイ． キング
ジェイムズ ザ サード ミーダー
アンソニー マニング
ジャン ヒルソン
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モメンタ ファーマシューティカルズ インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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JP2019504902A 2016-07-29 2017-07-31 Ｆｃｒｎ抗体及びその使用方法 Active JP7094941B2 (ja)

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JP2022100315A JP7442575B2 (ja) 2016-07-29 2022-06-22 Ｆｃｒｎ抗体及びその使用方法
JP2024023875A JP2024059765A (ja) 2016-07-29 2024-02-20 Ｆｃｒｎ抗体及びその使用方法

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US201662368803P 2016-07-29 2016-07-29
US201662368770P 2016-07-29 2016-07-29
US62/368,803 2016-07-29
US62/368,770 2016-07-29
PCT/US2017/044765 WO2018023136A1 (en) 2016-07-29 2017-07-31 Fcrn antibodies and methods of use thereof

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EP (2) EP3491025B1 (enExample)
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KR (3) KR20240151878A (enExample)
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AU (1) AU2017301915B2 (enExample)
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021506786A (ja) * 2017-12-13 2021-02-22 モメンタ ファーマシューティカルズ インコーポレイテッド ＦｃＲｎ抗体およびその使用方法
JP2021061854A (ja) * 2015-01-30 2021-04-22 モメンタ ファーマシューティカルズ インコーポレイテッド ＦｃＲｎ抗体およびその使用方法
JP2022126783A (ja) * 2016-07-29 2022-08-30 モメンタ ファーマシューティカルズ インコーポレイテッド Ｆｃｒｎ抗体及びその使用方法

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US11673955B2 (en) 2017-05-11 2023-06-13 National University Of Singapore Targeted prevention of maternal to foetal vertical transmission of infection
CA3081144A1 (en) 2017-12-08 2019-06-13 Argenx Bvba Use of fcrn antagonists for treatment of generalized myasthenia gravis
CN112153983B (zh) * 2018-05-23 2024-09-13 杰克逊实验室 抗ngly-1抗体及使用方法
MX2020013195A (es) 2018-06-08 2021-02-26 Argenx Bvba Composiciones y metodos para el tratamiento de la trombocitopenia inmunitaria.
WO2020023310A1 (en) * 2018-07-20 2020-01-30 Williams Eva Compositions of fcrn antibodies and methods of use thereof
AU2019307959B2 (en) * 2018-07-20 2025-09-25 Momenta Pharmaceuticals, Inc. FcRn antibody compositions
EP3969125A4 (en) * 2019-05-17 2023-01-11 Alexion Pharmaceuticals, Inc. USE OF ANTI-FCRN ANTIBODIES IN THE TREATMENT OF PEMPHIGHUS AND PEMPHIGOID DISEASES
AU2020319897A1 (en) * 2019-08-01 2022-02-24 Momenta Pharmaceuticals, Inc. FcRn antibodies and methods of use thereof
AU2020387399A1 (en) * 2019-11-19 2022-05-19 Immunovant Sciences Gmbh Methods of treating warm autoimmune hemolytic anemia using anti-FcRn antibodies
TW202140552A (zh) 2020-01-08 2021-11-01 比利時商阿根思公司 用於治療天皰瘡病症的方法
WO2023030501A1 (zh) * 2021-09-03 2023-03-09 舒泰神（北京）生物制药股份有限公司 特异性识别FcRn的抗体及其应用
CN113912730B (zh) * 2021-12-14 2022-03-04 北京科诺信诚科技有限公司 缓释的抗FcRn抗体或抗原结合片段及其应用
CA3258002A1 (en) 2022-06-15 2023-12-21 argenx BV FCRN BINDING MOLECULES AND METHODS OF USE
AR131560A1 (es) * 2023-01-06 2025-04-09 argenx BV Métodos para tratar pots mediante el uso de antagonistas de fcrn

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JP2011523351A (ja) 2008-04-25 2011-08-11 ダイアックス、コープ ＦｃＲｎに対する抗体及びその使用
JP2014523737A (ja) 2011-06-02 2014-09-18 ダイアックス コーポレーション Ｆｃレセプター結合タンパク質
JP6853178B2 (ja) 2015-01-30 2021-03-31 モメンタ ファーマシューティカルズ インコーポレイテッド ＦｃＲｎ抗体およびその使用方法

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