JP7092502B2 - ハイドロゲル薬物送達インプラント - Google Patents

ハイドロゲル薬物送達インプラント Download PDF

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Publication number
JP7092502B2
JP7092502B2 JP2017531184A JP2017531184A JP7092502B2 JP 7092502 B2 JP7092502 B2 JP 7092502B2 JP 2017531184 A JP2017531184 A JP 2017531184A JP 2017531184 A JP2017531184 A JP 2017531184A JP 7092502 B2 JP7092502 B2 JP 7092502B2
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hydrogel
particles
therapeutic agent
precursor
functional group
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JP2017537130A5 (https=
JP2017537130A (ja
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ピーター・ジャレット
ラミ・エル－ハイエク
アマルプリート・エス・ソーニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2017531184A 2014-12-10 2015-12-10 ハイドロゲル薬物送達インプラント Active JP7092502B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462089994P 2014-12-10 2014-12-10
US62/089,994 2014-12-10
PCT/US2015/064975 WO2016094646A1 (en) 2014-12-10 2015-12-10 Hydrogel drug delivery implants

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020201207A Division JP2021046429A (ja) 2014-12-10 2020-12-03 ハイドロゲル薬物送達インプラント

Publications (3)

Publication Number Publication Date
JP2017537130A JP2017537130A (ja) 2017-12-14
JP2017537130A5 JP2017537130A5 (https=) 2019-01-24
JP7092502B2 true JP7092502B2 (ja) 2022-06-28

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Family Applications (2)

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JP2017531184A Active JP7092502B2 (ja) 2014-12-10 2015-12-10 ハイドロゲル薬物送達インプラント
JP2020201207A Pending JP2021046429A (ja) 2014-12-10 2020-12-03 ハイドロゲル薬物送達インプラント

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JP2020201207A Pending JP2021046429A (ja) 2014-12-10 2020-12-03 ハイドロゲル薬物送達インプラント

Country Status (8)

Country Link
US (2) US20160166504A1 (https=)
EP (2) EP3229779B1 (https=)
JP (2) JP7092502B2 (https=)
KR (1) KR20170117384A (https=)
CN (2) CN120501693A (https=)
AU (1) AU2015360469B2 (https=)
CA (1) CA2969716C (https=)
WO (1) WO2016094646A1 (https=)

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US9855317B2 (en) 2015-04-27 2018-01-02 Reflex Medical, Inc. Systems and methods for sympathetic cardiopulmonary neuromodulation
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US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
CN108367079B (zh) 2015-11-12 2022-11-22 灰色视觉公司 用于治疗的聚集性微粒
KR20180086468A (ko) 2015-11-25 2018-07-31 인셉트, 엘엘씨 형상 변형 약물 전달 장치 및 방법
US11246879B2 (en) 2016-02-09 2022-02-15 Tulai Therapeutics, Inc. Methods, agents, and devices for local neuromodulation of autonomic nerves
WO2017165449A1 (en) * 2016-03-22 2017-09-28 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Thermoresponsive hydrogel containing polymer microparticles for noninvasive ocular biologic delivery
US11154547B2 (en) 2016-06-29 2021-10-26 Tulavi Therapeutics, Inc. Treatment of sepsis and related inflammatory conditions by local neuromodulation of the autonomic nervous system
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US20210315587A1 (en) 2018-07-02 2021-10-14 Tulavi Therapeutics, Inc. Methods and devices for in situ formed nerve cap with rapid release
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WO2020102810A1 (en) 2018-11-16 2020-05-22 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Thermoresponsive gel eye drop for ocular delivery of cysteamine
CN110772376A (zh) * 2019-11-20 2020-02-11 韩熠 一种用于婴幼儿及儿童的医用眼贴及其制备方法
JP7667747B2 (ja) * 2020-01-14 2025-04-23 持田製薬株式会社 アルギン酸塩を使用した対象の処置のための組合せ及び方法
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CN113230019A (zh) * 2021-04-16 2021-08-10 南京佑羲医药科技有限公司 一种用于眼球玻璃体内植入的长效缓释给药装置
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Also Published As

Publication number Publication date
WO2016094646A1 (en) 2016-06-16
US20160166504A1 (en) 2016-06-16
US20260060921A1 (en) 2026-03-05
CN120501693A (zh) 2025-08-19
CN107205922A (zh) 2017-09-26
AU2015360469A1 (en) 2017-06-22
KR20170117384A (ko) 2017-10-23
EP3229779B1 (en) 2021-02-03
EP3858329A1 (en) 2021-08-04
JP2021046429A (ja) 2021-03-25
AU2015360469B2 (en) 2021-03-25
EP3229779A1 (en) 2017-10-18
CA2969716C (en) 2023-12-19
CA2969716A1 (en) 2016-06-16
JP2017537130A (ja) 2017-12-14

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