JP7074750B2 - カルバモイルフェニルアラニノール化合物およびその使用 - Google Patents
カルバモイルフェニルアラニノール化合物およびその使用 Download PDFInfo
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- JP7074750B2 JP7074750B2 JP2019518480A JP2019518480A JP7074750B2 JP 7074750 B2 JP7074750 B2 JP 7074750B2 JP 2019518480 A JP2019518480 A JP 2019518480A JP 2019518480 A JP2019518480 A JP 2019518480A JP 7074750 B2 JP7074750 B2 JP 7074750B2
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/62—Compounds containing any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylcarbamates
- C07C271/66—Y being a hetero atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/58—Y being a hetero atom
- C07C275/60—Y being an oxygen atom, e.g. allophanic acids
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- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
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- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
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| PCT/US2017/055598 WO2018067971A1 (en) | 2016-10-06 | 2017-10-06 | Carbamoyl phenylalaninol compounds and uses therof |
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| US11986451B1 (en) | 2016-07-22 | 2024-05-21 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12478604B1 (en) | 2016-07-22 | 2025-11-25 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US12186296B1 (en) | 2016-07-22 | 2025-01-07 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
| US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
| RU2020108634A (ru) | 2017-07-31 | 2021-09-02 | Джаз Фармасьютикалз Айрлэнд Лимитед | Аналоги карбамоилфенилаланинола и способы их применения |
| AU2020231916B2 (en) | 2019-03-01 | 2025-08-28 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
| US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
| US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
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2017
- 2017-10-06 SG SG11201903076QA patent/SG11201903076QA/en unknown
- 2017-10-06 JP JP2019518480A patent/JP7074750B2/ja active Active
- 2017-10-06 CA CA3039045A patent/CA3039045A1/en not_active Abandoned
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- 2017-10-06 EP EP23199791.7A patent/EP4316592A3/en active Pending
- 2017-10-06 US US16/338,925 patent/US10710958B2/en active Active
- 2017-10-06 WO PCT/US2017/055598 patent/WO2018067971A1/en not_active Ceased
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| JP2008545795A (ja) | 2005-06-08 | 2008-12-18 | アブダラー アーナオウ | 睡眠覚醒障害の治療 |
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| US20190218175A1 (en) | 2019-07-18 |
| EP3523275A1 (en) | 2019-08-14 |
| EP4316592A3 (en) | 2024-05-01 |
| US10710958B2 (en) | 2020-07-14 |
| KR20190072561A (ko) | 2019-06-25 |
| US20200290955A1 (en) | 2020-09-17 |
| MY202185A (en) | 2024-04-15 |
| KR102616545B1 (ko) | 2023-12-26 |
| EP4316592A2 (en) | 2024-02-07 |
| US20250059136A1 (en) | 2025-02-20 |
| EP3523275B1 (en) | 2023-09-27 |
| WO2018067971A1 (en) | 2018-04-12 |
| US20220098145A1 (en) | 2022-03-31 |
| JP2020503246A (ja) | 2020-01-30 |
| US11149000B2 (en) | 2021-10-19 |
| US20240018098A1 (en) | 2024-01-18 |
| SG11201903076QA (en) | 2019-05-30 |
| CA3039045A1 (en) | 2018-04-12 |
| PH12019500751A1 (en) | 2019-08-05 |
| ES2964943T3 (es) | 2024-04-10 |
| US11780805B2 (en) | 2023-10-10 |
| CN110049966A (zh) | 2019-07-23 |
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