JP7069145B2 - 軟質固定インプラントを備えた組織修復アセンブリおよびシステム - Google Patents
軟質固定インプラントを備えた組織修復アセンブリおよびシステム Download PDFInfo
- Publication number
- JP7069145B2 JP7069145B2 JP2019521418A JP2019521418A JP7069145B2 JP 7069145 B2 JP7069145 B2 JP 7069145B2 JP 2019521418 A JP2019521418 A JP 2019521418A JP 2019521418 A JP2019521418 A JP 2019521418A JP 7069145 B2 JP7069145 B2 JP 7069145B2
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- Japan
- Prior art keywords
- suture
- tissue repair
- anchor body
- implant
- eyelet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0406—Pledgets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0409—Instruments for applying suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0414—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having a suture-receiving opening, e.g. lateral opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0445—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors cannulated, e.g. with a longitudinal through-hole for passage of an instrument
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0448—Additional elements on or within the anchor
- A61B2017/045—Additional elements on or within the anchor snug fit within the anchor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0448—Additional elements on or within the anchor
- A61B2017/0453—Additional elements on or within the anchor threaded elements, e.g. set screws
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0458—Longitudinal through hole, e.g. suture blocked by a distal suture knot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0459—Multiple holes in the anchor through which the suture extends and locking the suture when tension is applied
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0469—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery
- A61B2017/0475—Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery using sutures having a slip knot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/04—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials
- A61B2017/0496—Surgical instruments, devices or methods for suturing wounds; Holders or packages for needles or suture materials for tensioning sutures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0817—Structure of the anchor
- A61F2002/0823—Modular anchors comprising a plurality of separate parts
- A61F2002/0835—Modular anchors comprising a plurality of separate parts with deformation of anchor parts, e.g. expansion of dowel by set screw
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0847—Mode of fixation of anchor to tendon or ligament
- A61F2002/0852—Fixation of a loop or U-turn, e.g. eyelets, anchor having multiple holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/08—Muscles; Tendons; Ligaments
- A61F2/0811—Fixation devices for tendons or ligaments
- A61F2002/0876—Position of anchor in respect to the bone
- A61F2002/0888—Anchor in or on a blind hole or on the bone surface without formation of a tunnel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Rehabilitation Therapy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662417058P | 2016-11-03 | 2016-11-03 | |
| US62/417,058 | 2016-11-03 | ||
| US201762456188P | 2017-02-08 | 2017-02-08 | |
| US62/456,188 | 2017-02-08 | ||
| PCT/US2017/059943 WO2018085663A1 (en) | 2016-11-03 | 2017-11-03 | Tissue repair assembly and system with soft anchoring implant |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019536518A JP2019536518A (ja) | 2019-12-19 |
| JP2019536518A5 JP2019536518A5 (enExample) | 2020-11-12 |
| JP7069145B2 true JP7069145B2 (ja) | 2022-05-17 |
Family
ID=60409394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019521418A Active JP7069145B2 (ja) | 2016-11-03 | 2017-11-03 | 軟質固定インプラントを備えた組織修復アセンブリおよびシステム |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US11452516B2 (enExample) |
| EP (1) | EP3534803B1 (enExample) |
| JP (1) | JP7069145B2 (enExample) |
| CN (1) | CN109890303B (enExample) |
| AU (1) | AU2017355492B2 (enExample) |
| WO (1) | WO2018085663A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10849734B2 (en) * | 2018-08-16 | 2020-12-01 | Arthrex, Inc. | Methods of tissue repairs |
| EP3738520B1 (en) * | 2019-05-16 | 2024-01-24 | Smith & Nephew, Inc. | Tissue repair assembly |
| CN113853170A (zh) * | 2019-06-14 | 2021-12-28 | 史密夫和内修有限公司 | 软锚固组织修复组件和系统 |
| CN110215247A (zh) * | 2019-06-25 | 2019-09-10 | 上海利格泰生物科技有限公司 | 圆鞘多缝线锚钉及植入装置 |
| CN110215246A (zh) * | 2019-06-25 | 2019-09-10 | 上海利格泰生物科技有限公司 | 扁鞘缝线锚钉及植入装置 |
| CN110215248A (zh) * | 2019-06-25 | 2019-09-10 | 上海利格泰生物科技有限公司 | 扁鞘多缝线锚钉及植入装置 |
| CN110215245A (zh) * | 2019-06-25 | 2019-09-10 | 上海利格泰生物科技有限公司 | 圆鞘缝线锚钉及植入装置 |
| EP4096530B1 (en) * | 2020-01-31 | 2025-10-22 | Paragon 28, Inc. | Knotless soft tissue implant systems |
| CN115460994A (zh) | 2020-05-27 | 2022-12-09 | 史密夫和内修有限公司 | 组织修复系统 |
| CN114469213B (zh) * | 2020-11-13 | 2025-02-14 | 纳通生物科技(北京)有限公司 | 一种新型全线锚钉及植入系统 |
| CN114469214B (zh) * | 2020-11-13 | 2025-03-14 | 纳通生物科技(北京)有限公司 | 一种软组织修复装置 |
| CN112515722B (zh) * | 2020-12-01 | 2024-05-24 | 花沐医疗科技(上海)有限公司 | 一种全缝线锚钉结构及其植入装置 |
| US12453545B2 (en) * | 2021-04-08 | 2025-10-28 | Integrity Orthopaedics, Inc. | Tensionable and lockable soft suture anchors and anchor arrays for anatomical attachment of soft tissue to bone |
| US11375991B1 (en) * | 2021-04-08 | 2022-07-05 | Integrity Orthopaedics, Inc. | Tensionable and lockable micro suture anchors and anchor arrays for anatomical attachment of soft tissue to bone |
| CN113208675B (zh) * | 2021-05-24 | 2022-05-10 | 杭州锐健马斯汀医疗器材有限公司 | 一种复合缝线锚植入装置 |
| AU2022382910B2 (en) | 2021-11-04 | 2025-02-20 | Smith & Nephew Asia Pacific Pte. Limited | Knotless soft anchor system |
| CN114366204B (zh) * | 2022-01-13 | 2022-12-30 | 北京天星博迈迪医疗器械有限公司 | 一种全缝线锚钉及植入设备 |
| CN114652379B (zh) * | 2022-03-16 | 2023-09-05 | 上海利格泰生物科技股份有限公司 | 固定器械及其制造方法和医用固定装置 |
| CN115089343B (zh) * | 2022-06-08 | 2023-11-07 | 上海利格泰生物科技股份有限公司 | 医用固定器械及其制造方法 |
| CN115089243A (zh) * | 2022-06-08 | 2022-09-23 | 上海利格泰生物科技有限公司 | 医用固定器械及其制造方法 |
| CN115192103A (zh) * | 2022-08-11 | 2022-10-18 | 杭州锐健马斯汀医疗器材有限公司 | 植入组件、缝合器及缝合方法 |
| CN115317051B (zh) * | 2022-08-31 | 2023-10-20 | 上海利格泰生物科技股份有限公司 | 一种用于修复软组织的锚钉及锚钉系统 |
| US20240341750A1 (en) * | 2023-04-17 | 2024-10-17 | Arthrex, Inc. | Methods of Tissue Repairs |
| WO2025175041A1 (en) * | 2024-02-13 | 2025-08-21 | Holmes Jr S Wendell | Knotless suture anchors |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2012520141A (ja) | 2009-03-11 | 2012-09-06 | ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 糸通し可能結び目軟組織欠損修復システム |
| US20120239085A1 (en) | 2010-09-16 | 2012-09-20 | Ryan Schlotterback | Suture implant component and suture implant mechanism including such a component |
| US20140277133A1 (en) | 2013-03-12 | 2014-09-18 | Arthrocare Corporation | Tissue repair assembly |
| US20150173739A1 (en) | 2013-12-20 | 2015-06-25 | Arthrocare Corporation | Knotless all suture tissue repair |
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| US10058319B2 (en) | 2009-07-17 | 2018-08-28 | Pivot Medical, Inc. | Method and apparatus for attaching tissue to bone, including the provision and use of a novel knotless suture anchor system, including a novel locking element |
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| US8828053B2 (en) | 2009-07-24 | 2014-09-09 | Depuy Mitek, Llc | Methods and devices for repairing and anchoring damaged tissue |
| US8790369B2 (en) * | 2009-07-24 | 2014-07-29 | Depuy Mitek, Llc | Apparatus and method for repairing tissue |
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| US8795334B2 (en) * | 2011-01-28 | 2014-08-05 | Smith & Nephew, Inc. | Tissue repair |
| US11116498B2 (en) | 2011-02-02 | 2021-09-14 | Syntorr Inc. | Variable denier yarn and suture |
| US10973622B2 (en) | 2011-04-25 | 2021-04-13 | Arthrex, Inc. | Internal brace for tissue repairs and reinforcements |
| WO2013003746A1 (en) | 2011-06-29 | 2013-01-03 | Pivot Medical, Inc. | Method and apparatus for re-attaching the labrum to the acetabulum, including the provision and use of a novel suture anchor system |
| US9421008B2 (en) | 2011-09-23 | 2016-08-23 | Arthrex, Inc. | Soft suture-based anchors |
| GB2509679B (en) * | 2011-11-14 | 2018-09-05 | Arthrocare Corp | Tissue repair assembly |
| US9345567B2 (en) | 2012-05-07 | 2016-05-24 | Medos International Sàrl | Systems, devices, and methods for securing tissue using snare assemblies and soft anchors |
| US8894684B2 (en) * | 2012-05-07 | 2014-11-25 | Medos International Sàrl | Systems, devices, and methods for securing tissue using a suture having one or more protrusions |
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2017
- 2017-11-03 AU AU2017355492A patent/AU2017355492B2/en active Active
- 2017-11-03 US US16/342,877 patent/US11452516B2/en active Active
- 2017-11-03 JP JP2019521418A patent/JP7069145B2/ja active Active
- 2017-11-03 EP EP17801191.2A patent/EP3534803B1/en active Active
- 2017-11-03 CN CN201780066550.5A patent/CN109890303B/zh active Active
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2012520141A (ja) | 2009-03-11 | 2012-09-06 | ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 糸通し可能結び目軟組織欠損修復システム |
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| US20150173739A1 (en) | 2013-12-20 | 2015-06-25 | Arthrocare Corporation | Knotless all suture tissue repair |
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| US11452516B2 (en) | 2022-09-27 |
| CN109890303B (zh) | 2022-09-09 |
| JP2019536518A (ja) | 2019-12-19 |
| US20190247039A1 (en) | 2019-08-15 |
| CN109890303A (zh) | 2019-06-14 |
| EP3534803B1 (en) | 2022-01-05 |
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| AU2017355492B2 (en) | 2022-12-15 |
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| US20240315689A1 (en) | 2024-09-26 |
| EP3534803A1 (en) | 2019-09-11 |
| US20220395267A1 (en) | 2022-12-15 |
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