JP7057748B2 - 遺伝子改変された抗第三者中枢性メモリーｔ細胞および免疫療法におけるその使用 - Google Patents

遺伝子改変された抗第三者中枢性メモリーｔ細胞および免疫療法におけるその使用 Download PDF

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JP7057748B2
JP7057748B2 JP2018501339A JP2018501339A JP7057748B2 JP 7057748 B2 JP7057748 B2 JP 7057748B2 JP 2018501339 A JP2018501339 A JP 2018501339A JP 2018501339 A JP2018501339 A JP 2018501339A JP 7057748 B2 JP7057748 B2 JP 7057748B2
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antigen
tcm
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イェアー ライズナー，
ノガ オア－ゲヴァ，
エラン オフィア，
ヤキ アイデルシュタイン，
ブドヴスキー， ロテム ギドロン
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Yeda Research and Development Co Ltd
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JP2018501339A 2015-07-16 2016-07-14 遺伝子改変された抗第三者中枢性メモリーｔ細胞および免疫療法におけるその使用 Active JP7057748B2 (ja)

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Application Number Priority Date Filing Date Title
US201562193229P 2015-07-16 2015-07-16
US201562193207P 2015-07-16 2015-07-16
US62/193,229 2015-07-16
US62/193,207 2015-07-16
PCT/IL2016/050775 WO2017009853A1 (en) 2015-07-16 2016-07-14 Genetically modified anti-third party central memory t cells and use of same in immunotherapy

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JP2018524987A JP2018524987A (ja) 2018-09-06
JP2018524987A5 JP2018524987A5 (https=) 2019-08-29
JP7057748B2 true JP7057748B2 (ja) 2022-04-20

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US (4) US10933124B2 (https=)
EP (2) EP3322424B1 (https=)
JP (1) JP7057748B2 (https=)
CN (3) CN108135938A (https=)
AU (1) AU2016291825B2 (https=)
CA (1) CA2991690A1 (https=)
DK (1) DK3322425T3 (https=)
ES (2) ES2946785T3 (https=)
IL (1) IL256916B2 (https=)
PL (2) PL3322425T3 (https=)
WO (2) WO2017009853A1 (https=)

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US9738872B2 (en) 2008-10-30 2017-08-22 Yeda Research And Development Co. Ltd. Anti third party central memory T cells, methods of producing same and use of same in transplantation and disease treatment
WO2013035099A1 (en) 2011-09-08 2013-03-14 Yeda Research And Development Co. Ltd. Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment
CA2942245C (en) * 2014-03-12 2021-11-02 Yeda Research And Development Co. Ltd. Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns
EP3322424B1 (en) 2015-07-16 2023-10-11 Yeda Research and Development Co., Ltd. Use of anti third party central memory t cells
IL263924B2 (en) 2016-06-27 2025-03-01 Yeda Res & Dev Voto cells produced from memory T cells
ES3064681T3 (en) 2017-01-18 2026-04-28 Yeda Res And Development Co Ltd Genetically modified veto cells and use of same in immunotherapy
US10751368B2 (en) 2017-01-18 2020-08-25 Yeda Research And Development Co. Ltd. Methods of transplantation and disease treatment
CN107573419A (zh) * 2017-01-24 2018-01-12 深圳市体内生物医药科技有限公司 一种增强t细胞抗肿瘤活性的核酸分子
CN107254489B (zh) * 2017-06-19 2021-06-18 河南省华隆生物技术有限公司 一种检测嵌合抗原受体或基因修饰的t细胞受体表达的方法和应用
SG11202007171PA (en) * 2018-02-02 2020-08-28 Univ Pennsylvania Modified monocytes/macrophages/dendritic cells expressing chimeric antigen receptors and uses in diseases and disorders associated with protein aggregates
US20210213066A1 (en) * 2018-05-18 2021-07-15 Children's National Medical Center Improved cell therapy compositions for hematopoietic stem cell transplant patients
US20210301255A1 (en) * 2018-09-10 2021-09-30 Atara Biotherapeutics, Inc. Methods for expanding antigen-specific car-t cells, compositions and uses related thereto
CN109536444B (zh) * 2018-12-11 2022-06-28 吉林省拓华生物科技有限公司 一种适用于恶性实体瘤肿瘤浸润t淋巴细胞的分离诱导方法
WO2020219812A1 (en) * 2019-04-26 2020-10-29 Allogene Therapeutics, Inc. Methods of manufacturing allogeneic car t cells
CN110358734B (zh) * 2019-06-13 2020-08-25 首都医科大学宣武医院 以Tcm为主要效应成分的CAR-T制备方法及其应用
CN114466925A (zh) * 2019-08-06 2022-05-10 耶达研究及发展有限公司 单倍体相合的干细胞移植中的抗病毒中央型记忆cd8+反抑细胞
CN110628717B (zh) * 2019-10-28 2020-10-30 上海科医联创生物科技有限公司 一种浸润性t细胞的培养方法
JP2023500277A (ja) * 2019-11-05 2023-01-05 イェダ リサーチ アンド デベロップメント カンパニー リミテッド Ｔ細胞媒介性自己免疫疾患の治療におけるベト細胞の使用
MX2022005418A (es) * 2019-11-05 2022-08-15 Yeda Res & Dev Uso de celulas de veto para el tratamiento de la enfermedad de celulas falciformes.
KR20230034198A (ko) * 2020-02-28 2023-03-09 케이에스큐 세러퓨틱스 인코포레이티드 종양 침윤 림프구의 활성화 및 확장 방법
EP4161536A4 (en) 2020-06-04 2024-08-14 Carisma Therapeutics Inc. Novel constructs for chimeric antigen receptors
IL300470A (en) * 2020-08-11 2023-04-01 Yeda res & development co ltd Veto type CAR-T cells
US20240001142A1 (en) * 2020-10-07 2024-01-04 Board Of Regents, The University Of Texas System Induction by low dose radiation of cancer cell targets for cell-based or small molecule therapy

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