JP6995752B2 - 細胞拡大培養方法及び治療用組成物 - Google Patents

細胞拡大培養方法及び治療用組成物 Download PDF

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JP6995752B2
JP6995752B2 JP2018530940A JP2018530940A JP6995752B2 JP 6995752 B2 JP6995752 B2 JP 6995752B2 JP 2018530940 A JP2018530940 A JP 2018530940A JP 2018530940 A JP2018530940 A JP 2018530940A JP 6995752 B2 JP6995752 B2 JP 6995752B2
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バラルカ・バネルジー
シャーロット・モーガン
グラハム・ヴィージー
ニコール・ハナー・パッカー
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レジニアス リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells

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  • Dermatology (AREA)
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  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2018530940A 2015-09-08 2016-09-08 細胞拡大培養方法及び治療用組成物 Expired - Fee Related JP6995752B2 (ja)

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JP2021203331A JP2022027928A (ja) 2015-09-08 2021-12-15 細胞拡大培養方法及び治療用組成物

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AU2015903658A AU2015903658A0 (en) 2015-09-08 Cell expansion methods and therapeutic compositions
AU2015903658 2015-09-08
PCT/AU2016/000316 WO2017041133A1 (en) 2015-09-08 2016-09-08 Cell expansion methods and therapeutic compositions

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JP2018526447A5 JP2018526447A5 (enExample) 2019-10-24
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JP2021203331A Pending JP2022027928A (ja) 2015-09-08 2021-12-15 細胞拡大培養方法及び治療用組成物
JP2022172508A Pending JP2022186992A (ja) 2015-09-08 2022-10-27 細胞拡大培養方法及び治療用組成物

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JP2022172508A Pending JP2022186992A (ja) 2015-09-08 2022-10-27 細胞拡大培養方法及び治療用組成物

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EP (1) EP3347449A4 (enExample)
JP (3) JP6995752B2 (enExample)
KR (1) KR20180043834A (enExample)
CN (1) CN108348555B (enExample)
AU (1) AU2016321448B2 (enExample)
CA (1) CA3035931A1 (enExample)
HK (1) HK1252778A1 (enExample)
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Publication number Priority date Publication date Assignee Title
AU2016342387B2 (en) * 2015-10-23 2021-12-09 Rigshospitalet Stem cell therapy based on adipose-derived stem cells
WO2018213795A1 (en) * 2017-05-18 2018-11-22 The Board Of Trustees Of The Leland Stanford Junior University Targeted in situ therapeutic delivery of secreted factors from stem cells for treatment of damaged tissue
CA3103043A1 (en) 2018-06-15 2019-12-19 Luis Marinas Pardo Pharmaceutical composition for dermatology and uses thereof
CN109022360A (zh) * 2018-07-03 2018-12-18 湖南未名三胞转化医学科技有限公司 自体脂肪干细胞共培养促进外周血造血干细胞增殖方法
CN110106142B (zh) * 2019-05-30 2020-05-12 深圳阿尔法生物科技有限公司 一种制备“百亿”级脂肪源再生细胞的生产工艺
CN111073857A (zh) * 2019-12-30 2020-04-28 深圳爱生再生医学科技有限公司 一种治疗关节炎的干细胞生物制品及其制备方法与应用
KR102193175B1 (ko) * 2020-04-07 2020-12-18 주식회사 엑소스템텍 통증조절인자를 함유한 줄기세포유래 엑소좀 및 그 용도
CO2020012570A1 (es) 2020-10-08 2022-04-08 Inst Distrital De Ciencia Biotecnologia E Innovacion En Salud Idcbis Método de estimulación de células mesenquimales para inducir expresión de factores inmunomoduladores
US20230365937A1 (en) * 2020-10-26 2023-11-16 Hadasit Medical Research Services And Development Ltd. Mesenchymal stem cells and their culture
BR102022016233A2 (pt) * 2022-08-16 2024-02-27 Omics Biotecnologia Animal Ltda Concentrado de proteínas e peptídeos derivados de células estromais mesenquimais, método de obtenção e uso de concentrado

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005085421A2 (en) 2004-03-02 2005-09-15 The University Of Manchester Treatment of spinal conditions
US20140219972A1 (en) 2013-02-05 2014-08-07 The Board Of Trustees Of The Leland Stanford Junior University Tissue engineering using progenitor cells to catalyze tissue formation by primary cells

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Publication number Priority date Publication date Assignee Title
WO2008034803A1 (en) * 2006-09-18 2008-03-27 Medizinische Universität Graz Plasma-free platelet lysate for use as a supplement in cell cultures and for the preparation of cell therapeutics
PL2611906T3 (pl) * 2010-08-31 2024-05-27 Gallant Pet, Inc. Ogólnoustrojowe terapie allogenicznymi komórkami macierzystymi do leczenia chorób u kotów i psów
SG10201606745XA (en) 2011-09-23 2016-10-28 Cell Ideas Pty Ltd Therapeutics using adipose cells and cell secretions
EP3405204B1 (en) * 2016-08-26 2025-06-25 Restem Llc Composition and methods of using umbilical cord lining stem cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005085421A2 (en) 2004-03-02 2005-09-15 The University Of Manchester Treatment of spinal conditions
US20140219972A1 (en) 2013-02-05 2014-08-07 The Board Of Trustees Of The Leland Stanford Junior University Tissue engineering using progenitor cells to catalyze tissue formation by primary cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VOGEL, Julia P. et al，Platelet-rich plasma improves expansion of human mesenchymal stemcells and retains differentiation capacity and in.vivo bone formation in calcium phosphate ceramics，Platelets，Vol. 17, No. 7，2006年，p. 462-469

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JP2022027928A (ja) 2022-02-14
HK1252778A1 (zh) 2019-05-31
TWI760313B (zh) 2022-04-11
KR20180043834A (ko) 2018-04-30
AU2016321448B2 (en) 2023-02-02
WO2017041133A1 (en) 2017-03-16
EP3347449A1 (en) 2018-07-18
US20210260129A1 (en) 2021-08-26
JP2022186992A (ja) 2022-12-15
AU2016321448A1 (en) 2018-03-15
CN108348555B (zh) 2022-07-08
CN108348555A (zh) 2018-07-31
US20180236003A1 (en) 2018-08-23
EP3347449A4 (en) 2019-03-20
CA3035931A1 (en) 2017-03-16
TW201720922A (zh) 2017-06-16
JP2018526447A (ja) 2018-09-13

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