JP6990244B2 - ヒトｃｄ１２３を標的とするキメラ受容体リガンド及びその応用 - Google Patents

ヒトｃｄ１２３を標的とするキメラ受容体リガンド及びその応用 Download PDF

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JP6990244B2
JP6990244B2 JP2019531525A JP2019531525A JP6990244B2 JP 6990244 B2 JP6990244 B2 JP 6990244B2 JP 2019531525 A JP2019531525 A JP 2019531525A JP 2019531525 A JP2019531525 A JP 2019531525A JP 6990244 B2 JP6990244 B2 JP 6990244B2
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chimeric receptor
cells
receptor ligand
amino acid
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JP2019532668A5 (enExample
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チーチュアン、チュワン
シャオフー、ファン
レイ、ヤン
ピンヤン、ワン
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ナンキン レジェンド バイオテック カンパニー リミテッド
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JP2019531525A 2016-08-31 2017-08-31 ヒトｃｄ１２３を標的とするキメラ受容体リガンド及びその応用 Expired - Fee Related JP6990244B2 (ja)

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CN201610795955.XA CN107793481A (zh) 2016-08-31 2016-08-31 一种靶向人cd123的嵌合受体配体及其应用
CN201610795955.X 2016-08-31
PCT/CN2017/099941 WO2018041220A1 (zh) 2016-08-31 2017-08-31 一种靶向人cd123的嵌合受体配体及其应用

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CN110157678A (zh) * 2018-02-12 2019-08-23 深圳宾德生物技术有限公司 一种靶向性t淋巴细胞及其制备方法和应用
KR20210031898A (ko) * 2018-07-13 2021-03-23 난징 레전드 바이오테크 씨오., 엘티디. 전염병을 치료하기 위한 공동수용체 시스템
CN109970869A (zh) * 2019-04-12 2019-07-05 南京卡提医学科技有限公司 一种靶向人trail死亡受体的嵌合受体配体及其应用
CN110904048A (zh) * 2019-12-04 2020-03-24 合肥中科干细胞再生医学有限公司 一种car-cd123t2嵌合抗原受体t细胞及其应用
WO2023000036A1 (en) * 2021-07-22 2023-01-26 The Westmead Institute for Medical Research Chimeric antigen receptor useful in treating cancer
WO2023010126A2 (en) * 2021-07-29 2023-02-02 Vor Biopharma Inc. Chimeric antigen receptors for treatment of cancer
CN117126856A (zh) * 2022-05-20 2023-11-28 上海雅科生物科技有限公司 以bcma胞外结构域为标记的基因、多肽、重组表达载体、基因工程化细胞及其应用
CN115819622A (zh) * 2022-09-26 2023-03-21 湖南省人民医院(湖南师范大学附属第一医院) 针对b系白血病或淋巴瘤的双靶点car结构及药物组合物
CN116179495B (zh) * 2022-11-28 2025-06-06 上海恩凯细胞技术有限公司 转基因免疫细胞及其应用
CN117659196B (zh) * 2023-12-12 2024-08-23 成都优赛诺生物科技有限公司 一种靶向cd7的单域抗体、嵌合抗原受体及其应用
CN117964783A (zh) * 2024-02-05 2024-05-03 浙江康佰裕生物科技有限公司 一种靶向cll1的嵌合抗原受体及其应用

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JP2012501180A (ja) 2008-08-26 2012-01-19 シティ・オブ・ホープ Ｔ細胞の抗腫瘍エフェクター機能増進のための方法および組成物

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EP3207941B3 (en) * 2006-09-07 2020-08-19 Scott & White Memorial Hospital Methods and compositions based on diphtheria toxin-interleukin-3 conjugates
AU2013312838B2 (en) * 2012-09-04 2018-11-29 Cellectis Multi-chain chimeric antigen receptor and uses thereof
US9657105B2 (en) * 2013-03-15 2017-05-23 City Of Hope CD123-specific chimeric antigen receptor redirected T cells and methods of their use
TR201910814T4 (tr) * 2014-03-19 2019-08-21 Cellectis Kanser immünoterapisi için cd123 spesifik kimerik antijen reseptörleri.
EP3158064A1 (en) * 2014-06-17 2017-04-26 Cellectis Cd123 specific multi-chain chimeric antigen receptor
EP3712171A1 (en) * 2014-08-19 2020-09-23 Novartis AG Treatment of cancer using a cd123 chimeric antigen receptor

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
JP2012501180A (ja) 2008-08-26 2012-01-19 シティ・オブ・ホープ Ｔ細胞の抗腫瘍エフェクター機能増進のための方法および組成物

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Title
The Journal of Biological Chemistry，1995年，vol.270, no.40，p.23754-23760

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US20190225668A1 (en) 2019-07-25
CN107793481A (zh) 2018-03-13
WO2018041220A1 (zh) 2018-03-08
EP3508504A4 (en) 2020-04-22
US11401317B2 (en) 2022-08-02
EP3508504A1 (en) 2019-07-10
JP2019532668A (ja) 2019-11-14

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