JP6967308B1 - 胎児付属物由来組織細胞培養上清を含む脳神経障害治療剤 - Google Patents
胎児付属物由来組織細胞培養上清を含む脳神経障害治療剤 Download PDFInfo
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- JP6967308B1 JP6967308B1 JP2020149878A JP2020149878A JP6967308B1 JP 6967308 B1 JP6967308 B1 JP 6967308B1 JP 2020149878 A JP2020149878 A JP 2020149878A JP 2020149878 A JP2020149878 A JP 2020149878A JP 6967308 B1 JP6967308 B1 JP 6967308B1
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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- A—HUMAN NECESSITIES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- A61K35/48—Reproductive organs
- A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/21—Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2306—Interleukin-6 (IL-6)
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- Zoology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Reproductive Health (AREA)
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- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pregnancy & Childbirth (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Neurology (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
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Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2021/024837 WO2022004816A1 (ja) | 2020-06-30 | 2021-06-30 | 胎児付属物由来組織細胞培養上清を含む脳神経障害治療剤 |
| CN202180047221.2A CN115811981A (zh) | 2020-06-30 | 2021-06-30 | 包含胎儿附属物来源组织细胞培养上清的脑神经损伤治疗剂 |
| US18/003,425 US20230242870A1 (en) | 2020-06-30 | 2021-06-30 | Cranial nerve disorder therapeutic agent including culture supernatant of tissue cells derived from fetal appendage |
| JP2022534097A JPWO2022004816A1 (https=) | 2020-06-30 | 2021-06-30 | |
| EP21832276.6A EP4173629A4 (en) | 2020-06-30 | 2021-06-30 | THERAPEUTIC AGENT FOR CRANIAL NERVE DISEASE USING CULTURE SUPERNATANT OF TISSUE CELLS FROM THE FETAL APPENDIX |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020113456 | 2020-06-30 | ||
| JP2020113456 | 2020-06-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP6967308B1 true JP6967308B1 (ja) | 2021-11-17 |
| JP2022016722A JP2022016722A (ja) | 2022-01-24 |
Family
ID=78509585
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020149878A Active JP6967308B1 (ja) | 2020-06-30 | 2020-09-07 | 胎児付属物由来組織細胞培養上清を含む脳神経障害治療剤 |
| JP2022534097A Pending JPWO2022004816A1 (https=) | 2020-06-30 | 2021-06-30 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022534097A Pending JPWO2022004816A1 (https=) | 2020-06-30 | 2021-06-30 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20230242870A1 (https=) |
| EP (1) | EP4173629A4 (https=) |
| JP (2) | JP6967308B1 (https=) |
| CN (1) | CN115811981A (https=) |
| WO (1) | WO2022004816A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2022004816A1 (https=) * | 2020-06-30 | 2022-01-06 | ||
| CN117679649A (zh) * | 2022-09-09 | 2024-03-12 | 北京达尔文细胞生物科技有限公司 | 射频装置在治疗面瘫连带运动中的应用 |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025100424A1 (ja) * | 2023-11-10 | 2025-05-15 | 国立大学法人 東京大学 | 急性脳症治療剤及び急性脳症の治療方法 |
| WO2025182103A1 (ja) * | 2024-02-28 | 2025-09-04 | セルソース株式会社 | 脳梗塞の機能予後改善用組成物 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5190556A (en) | 1991-03-19 | 1993-03-02 | O.B. Tech, Inc. | Cord cutter sampler |
| US5372581A (en) | 1993-07-21 | 1994-12-13 | Minneapolis Children's Services Corporation | Method and apparatus for placental blood collection |
| WO2002098361A2 (en) * | 2001-06-01 | 2002-12-12 | Xcyte Therapies, Inc. | T cell induced tissue repair and regeneration |
| WO2005001080A2 (en) * | 2003-06-27 | 2005-01-06 | Ethicon, Incorporated | Postpartum-derived cells for use in treatment of disease of the heart and circulatory system |
| WO2006071778A2 (en) * | 2004-12-23 | 2006-07-06 | Ethicon Incorporated | Treatment of parkinson's disease and related disorders using postpartum derived cells |
| EP2139497B1 (en) * | 2007-04-13 | 2013-11-06 | Stemnion, INC. | Methods for treating nervous system injury and disease |
| JP6095893B2 (ja) * | 2008-12-19 | 2017-03-15 | デピュイ・シンセス・プロダクツ・インコーポレイテッド | 傷害後の神経組織の再生および修復 |
| SG174551A1 (en) * | 2009-03-26 | 2011-10-28 | Ethicon Inc | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
| MX2013006592A (es) * | 2010-12-17 | 2014-02-06 | Anthrogenesis Corp | Tratamiento de lesion de la medula espinal y lesion traumatica de cerebro empleando celulas adherentes obtenidas del amnios. |
| US20120276215A1 (en) * | 2011-04-26 | 2012-11-01 | Riordan Neil H | Therapeutic Conditioned Media |
| CN104321426A (zh) * | 2012-03-28 | 2015-01-28 | 石匠株式会社 | 永生化干细胞以及以其生成物为有效成分的药物组合物和药物制剂 |
| US10167448B2 (en) * | 2013-12-12 | 2019-01-01 | Samsung Life Public Welfare Foundation | Pharmaceutical composition for treating cerebrovascular diseases, containing stem cell-derived exosome as active ingredient |
| DK3145493T3 (da) * | 2014-05-18 | 2022-10-31 | Childrens Medical Center | Fremgangsmåder og sammensætninger vedrørende exosomer |
| EP3307286B1 (en) * | 2015-06-12 | 2023-01-11 | Hudson Institute of Medical Research | Allogeneic mammalian amniotic exosomes for treating a fibrotic disease |
| WO2017204231A1 (ja) * | 2016-05-24 | 2017-11-30 | 国立大学法人 東京大学 | 臍帯由来細胞を含む脳障害の治療剤 |
| KR20190109389A (ko) * | 2016-11-03 | 2019-09-25 | 엑소스템 바이오텍 리미티드 | 간엽 줄기 세포 집단, 이들의 산물 및 이들의 용도 |
| CA3064064A1 (en) * | 2017-05-16 | 2018-11-22 | Exostem Biotec Ltd. | Methods of inhibiting aging and treating aging-related disorders |
| CA3069805A1 (en) * | 2017-07-14 | 2019-01-17 | Orbsen Therapeutics Limited | Cd39 stromal stem cells methods of isolation and use |
| JP2020093988A (ja) * | 2018-12-11 | 2020-06-18 | 株式会社 バイオミメティクスシンパシーズ | 腸溶性カプセル |
| JP6967308B1 (ja) * | 2020-06-30 | 2021-11-17 | 国立大学法人高知大学 | 胎児付属物由来組織細胞培養上清を含む脳神経障害治療剤 |
-
2020
- 2020-09-07 JP JP2020149878A patent/JP6967308B1/ja active Active
-
2021
- 2021-06-30 CN CN202180047221.2A patent/CN115811981A/zh active Pending
- 2021-06-30 WO PCT/JP2021/024837 patent/WO2022004816A1/ja not_active Ceased
- 2021-06-30 EP EP21832276.6A patent/EP4173629A4/en not_active Withdrawn
- 2021-06-30 US US18/003,425 patent/US20230242870A1/en active Pending
- 2021-06-30 JP JP2022534097A patent/JPWO2022004816A1/ja active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2022004816A1 (https=) * | 2020-06-30 | 2022-01-06 | ||
| CN117679649A (zh) * | 2022-09-09 | 2024-03-12 | 北京达尔文细胞生物科技有限公司 | 射频装置在治疗面瘫连带运动中的应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2022016722A (ja) | 2022-01-24 |
| US20230242870A1 (en) | 2023-08-03 |
| EP4173629A4 (en) | 2024-08-21 |
| CN115811981A (zh) | 2023-03-17 |
| EP4173629A1 (en) | 2023-05-03 |
| JPWO2022004816A1 (https=) | 2022-01-06 |
| WO2022004816A1 (ja) | 2022-01-06 |
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