JP6963719B2 - 抗インフルエンザ薬の調製におけるカンナビジオールの用途 - Google Patents

抗インフルエンザ薬の調製におけるカンナビジオールの用途 Download PDF

Info

Publication number
JP6963719B2
JP6963719B2 JP2020530715A JP2020530715A JP6963719B2 JP 6963719 B2 JP6963719 B2 JP 6963719B2 JP 2020530715 A JP2020530715 A JP 2020530715A JP 2020530715 A JP2020530715 A JP 2020530715A JP 6963719 B2 JP6963719 B2 JP 6963719B2
Authority
JP
Japan
Prior art keywords
influenza
virus
cannabidiol
group
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2020530715A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020530499A5 (enExample
JP2020530499A (ja
Inventor
張可
譚▲しん▼
李向東
于朝暉
Original Assignee
漢義生物科技(北京)有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 漢義生物科技(北京)有限公司 filed Critical 漢義生物科技(北京)有限公司
Publication of JP2020530499A publication Critical patent/JP2020530499A/ja
Publication of JP2020530499A5 publication Critical patent/JP2020530499A5/ja
Application granted granted Critical
Publication of JP6963719B2 publication Critical patent/JP6963719B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/658Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/70Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Physiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
JP2020530715A 2017-08-31 2017-08-31 抗インフルエンザ薬の調製におけるカンナビジオールの用途 Expired - Fee Related JP6963719B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2017/099956 WO2019041239A1 (zh) 2017-08-31 2017-08-31 大麻二酚在制备抗流感的药物中的用途

Publications (3)

Publication Number Publication Date
JP2020530499A JP2020530499A (ja) 2020-10-22
JP2020530499A5 JP2020530499A5 (enExample) 2020-12-03
JP6963719B2 true JP6963719B2 (ja) 2021-11-10

Family

ID=65524611

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020530715A Expired - Fee Related JP6963719B2 (ja) 2017-08-31 2017-08-31 抗インフルエンザ薬の調製におけるカンナビジオールの用途

Country Status (6)

Country Link
US (1) US11452707B2 (enExample)
EP (1) EP3677258B1 (enExample)
JP (1) JP6963719B2 (enExample)
AU (1) AU2017429312B2 (enExample)
CA (1) CA3073576C (enExample)
WO (1) WO2019041239A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113116867B (zh) * 2019-12-31 2022-08-23 汉义生物科技(北京)有限公司 一种预防和/或治疗流感的组合物
CN111249266B (zh) * 2020-03-06 2022-08-09 中国人民解放军海军军医大学 帕拉米韦在制备治疗感染性疾病引起炎症风暴的药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011005411A (es) * 2008-11-25 2011-06-16 Alder Biopharmaceuticals Inc Anticuerpos de il-6 y uso de los mismos.
FR2953410B1 (fr) * 2009-12-09 2012-02-24 Univ Claude Bernard Lyon Compositions antivirales pharmaceutiques ou veterinaires
US20130203715A1 (en) * 2010-07-20 2013-08-08 Pulmatrix, Inc. Use of trp channel agonists to treat infections
US9308213B2 (en) * 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
GB201018289D0 (en) * 2010-10-29 2010-12-15 Biocopea Ltd Treatment of respiratory disorders
RU2635188C2 (ru) * 2011-02-04 2017-11-09 ИнФёрст Хэлткэр Лимитед Композиции и способы для лечения хронического воспаления и воспалительных заболеваний
WO2016092539A1 (en) * 2014-12-07 2016-06-16 One World Cannabis Ltd Use of cannabis to treat migraine
US20160317468A1 (en) * 2015-04-28 2016-11-03 Raman Sankar Uses of cannabidiol for treatment of infantile spasms
US20180116998A1 (en) * 2015-05-13 2018-05-03 One World Cannabis Ltd Use of cannabis to treat fibromyalgia, methods and compositions thereof
JP7454332B2 (ja) * 2016-06-15 2024-03-22 オーハイ エナジェティクス ピービーシー 酸化ストレスを低減するための方法および組成物

Also Published As

Publication number Publication date
EP3677258A1 (en) 2020-07-08
US11452707B2 (en) 2022-09-27
AU2017429312A1 (en) 2020-04-16
CA3073576C (en) 2023-01-24
AU2017429312B2 (en) 2022-03-24
EP3677258A4 (en) 2020-09-09
US20200360336A1 (en) 2020-11-19
EP3677258B1 (en) 2022-02-09
JP2020530499A (ja) 2020-10-22
CA3073576A1 (en) 2019-03-07
WO2019041239A1 (zh) 2019-03-07

Similar Documents

Publication Publication Date Title
Belser et al. Influenza A virus transmission: contributing factors and clinical implications
Lee et al. Antiviral activity of ginseng extract against respiratory syncytial virus infection
KR101317318B1 (ko) 신종인플루엔자, 조류인플루엔자, 일반 및 독감감기, sars 바이러스 억제 효능을 갖는 오배자 추출물 또는 이로부터 분리된 화합물을 유효성분으로 함유하는 약학 조성물
CN103687599A (zh) 氯喹或氯丙嗪或其衍生物或它们的混合物在制备用于治疗和/或预防肺感染和损伤的药物中的用途
CN111467363A (zh) 索非布韦在制备预防和治疗冠状病毒的药物中的应用
CN111420024A (zh) 杆菌酞a在制备预防和治疗冠状病毒的药物中的应用
CN111407754A (zh) 卡谷氨酸在制备预防和治疗冠状病毒的药物中的应用
CN109419786B (zh) 大麻二酚在制备抗流感的药物中的用途
JP2026076345A (ja) 抗ウイルス処置としてのアゼラスチン
Singh et al. Pongamia pinnata L. seed-derived karanjin as prominent antiviral agent against Newcastle disease virus
JP2020530499A (ja) 抗インフルエンザ薬の調製におけるカンナビジオールの用途
CN111467355A (zh) 膦甲酸钠在制备预防和治疗冠状病毒的药物中的应用
KR101731607B1 (ko) 음양곽 추출물을 유효성분으로 함유하는 항 바이러스용 조성물
CN112694463B (zh) 一种异戊烯基色原酮类化合物在制备抗冠状病毒药物中的用途
CN117510409B (zh) 广谱抗病毒中药单体蝙蝠葛苏林碱、及其药物组合物和应用
CN108420815B (zh) 聚酮在抑制流感病毒中的应用
KR20230123906A (ko) 선학초(Agrimonia pilosa) 추출물과 오배자(Galla rhois)추출물의 혼합물을 유효성분으로 포함하는 인플루엔자 바이러스 감염증 예방, 치료 또는 개선용 조성물
CN112245424B (zh) 一种没药烷倍半萜结构类似物在制备抗冠状病毒药物中的用途
CN102112427B (zh) 新型二芳基庚酮类化合物及其使用
CN110721312A (zh) 用于治疗小儿呼吸道感染的药物组合物及其相关制剂
CN102112461B (zh) 新型二芳基庚酮系化合物及其应用
KR20230039782A (ko) 선학초(Agrimonia pilosa) 추출물과 오배자(Galla rhois) 추출물의 혼합물을 유효성분으로 포함하는 인플루엔자 바이러스 감염증 예방, 치료 또는 개선용 조성물
WO2020216349A1 (zh) 一种肠道病毒抑制剂
CN114732821A (zh) 西多福韦的前药在制备防治非洲猪瘟药物中的应用
CN117838698A (zh) 奥拉替尼在制备治疗流感病毒感染的药物中的应用

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200214

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20200214

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20210202

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20210426

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20210909

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20210925

R150 Certificate of patent or registration of utility model

Ref document number: 6963719

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

LAPS Cancellation because of no payment of annual fees