JP6944682B2 - ベンゾイミダゾール系化合物の製造方法 - Google Patents

ベンゾイミダゾール系化合物の製造方法 Download PDF

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Publication number
JP6944682B2
JP6944682B2 JP2020509138A JP2020509138A JP6944682B2 JP 6944682 B2 JP6944682 B2 JP 6944682B2 JP 2020509138 A JP2020509138 A JP 2020509138A JP 2020509138 A JP2020509138 A JP 2020509138A JP 6944682 B2 JP6944682 B2 JP 6944682B2
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formula
compound
iii
group
reaction
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JP2020509138A
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Japanese (ja)
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JP2020518661A (ja
JP2020518661A5 (enExample
Inventor
シュエジン リゥ
シュエジン リゥ
イン ハン
イン ハン
リァン ヤン
リァン ヤン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shandong Jitian Aroma Chemical CoLtd
Shandong Lunan Research Institute Of Coal Chemical Engineering And Technology
Zaozhuang University
Original Assignee
Shandong Jitian Aroma Chemical CoLtd
Shandong Lunan Research Institute Of Coal Chemical Engineering And Technology
Zaozhuang University
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP2020509138A 2017-07-19 2017-09-28 ベンゾイミダゾール系化合物の製造方法 Expired - Fee Related JP6944682B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201710589775.0A CN107445899A (zh) 2017-07-19 2017-07-19 一种苯并咪唑类化合物及其制备方法
CN201710589775.0 2017-07-19
PCT/CN2017/103942 WO2019015112A1 (zh) 2017-07-19 2017-09-28 一种苯并咪唑类化合物及其制备方法

Publications (3)

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JP2020518661A JP2020518661A (ja) 2020-06-25
JP2020518661A5 JP2020518661A5 (enExample) 2021-03-18
JP6944682B2 true JP6944682B2 (ja) 2021-10-06

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JP2020509138A Expired - Fee Related JP6944682B2 (ja) 2017-07-19 2017-09-28 ベンゾイミダゾール系化合物の製造方法

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US (1) US10787420B2 (enExample)
JP (1) JP6944682B2 (enExample)
CN (1) CN107445899A (enExample)
WO (1) WO2019015112A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110759903B (zh) * 2018-07-26 2022-10-28 南开大学 一种噻苯唑的合成新方法
CN108863820B (zh) * 2018-07-30 2021-07-06 枣庄学院 一种取代邻苯二胺的合成方法
CN108640876A (zh) * 2018-08-02 2018-10-12 华侨大学 一种多取代苯并咪唑衍生物及其制备方法
CN109020895B (zh) * 2018-08-07 2020-04-24 枣庄学院 一种金属催化的1-苄胺基取代苯并咪唑的合成方法
CN110256359A (zh) * 2019-06-20 2019-09-20 武汉工程大学 2-氨基苯并咪唑衍生物及其合成和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1576077A (en) * 1977-04-13 1980-10-01 Roussel Lab Ltd 4,5-dihydro-4-oxophyrrolo(1,2-)-quinoxaline-2-carboxylic acids and derivatives
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
JP2006522812A (ja) * 2003-04-11 2006-10-05 スミスクライン ビーチャム コーポレーション 複素環ｍｃｈｒ１アンタゴニスト
WO2008134354A1 (en) * 2007-04-27 2008-11-06 Array Biopharma, Inc. TNF-α PRODUCTION INHIBITOR
CN102985405B (zh) * 2010-07-02 2016-07-06 Aska制药株式会社 杂环化合物及p27Kip1分解抑制剂
WO2015171951A1 (en) * 2014-05-07 2015-11-12 The Regents Of The University Of Colorado, A Body Corporate 2-(4-aryl-1h-imidazol-1-yl)aniline compounds
MA40957A (fr) * 2014-10-09 2017-09-19 Biomarin Pharm Inc Inhibiteurs de biosynthèse d'héparane sulfate pour traiter des maladies
CN106946862B (zh) * 2017-03-31 2019-09-03 枣庄学院 1-烷烃-6-甲基-5-硝基-1h-苯并[d]咪唑类化合物及其制备方法
CN106866545B (zh) * 2017-03-31 2019-07-09 枣庄学院 1-环烷烃-5-硝基-1h-苯并[d]咪唑类化合物及其制备方法

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Publication number Publication date
JP2020518661A (ja) 2020-06-25
US10787420B2 (en) 2020-09-29
US20200002291A1 (en) 2020-01-02
CN107445899A (zh) 2017-12-08
WO2019015112A1 (zh) 2019-01-24

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