JP6916524B2 - 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 - Google Patents
機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 Download PDFInfo
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- JP6916524B2 JP6916524B2 JP2017552146A JP2017552146A JP6916524B2 JP 6916524 B2 JP6916524 B2 JP 6916524B2 JP 2017552146 A JP2017552146 A JP 2017552146A JP 2017552146 A JP2017552146 A JP 2017552146A JP 6916524 B2 JP6916524 B2 JP 6916524B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/101—Plasmid DNA for bacteria
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021030187A JP7156726B2 (ja) | 2015-04-06 | 2021-02-26 | 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562143560P | 2015-04-06 | 2015-04-06 | |
| US62/143,560 | 2015-04-06 | ||
| PCT/US2016/026161 WO2016164422A2 (en) | 2015-04-06 | 2016-04-06 | Biosynthetic amyloid-based materials displaying functional protein sequences |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021030187A Division JP7156726B2 (ja) | 2015-04-06 | 2021-02-26 | 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018517398A JP2018517398A (ja) | 2018-07-05 |
| JP2018517398A5 JP2018517398A5 (enExample) | 2019-05-16 |
| JP6916524B2 true JP6916524B2 (ja) | 2021-08-11 |
Family
ID=57072695
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017552146A Active JP6916524B2 (ja) | 2015-04-06 | 2016-04-06 | 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 |
| JP2021030187A Active JP7156726B2 (ja) | 2015-04-06 | 2021-02-26 | 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021030187A Active JP7156726B2 (ja) | 2015-04-06 | 2021-02-26 | 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20180258435A1 (enExample) |
| EP (1) | EP3280397A4 (enExample) |
| JP (2) | JP6916524B2 (enExample) |
| WO (1) | WO2016164422A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9815871B2 (en) | 2013-04-23 | 2017-11-14 | President And Fellows Of Harvard College | Genetic reprogramming of bacterial biofilms |
| JP6916524B2 (ja) | 2015-04-06 | 2021-08-11 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 |
| US11098133B2 (en) | 2016-05-19 | 2021-08-24 | President And Fellows Of Harvard College | Methods of making gels and films using curli nanofibers |
| FR3099648B1 (fr) * | 2019-07-30 | 2023-01-13 | Centre Nat Rech Scient | Membrane échangeuse d’ions |
| CN110585482B (zh) * | 2019-08-02 | 2022-03-01 | 大连理工大学 | 一种具有抗菌性能的杂萘联苯聚芳醚腈及其表面改性方法 |
| CN112608876B (zh) * | 2020-12-30 | 2024-02-09 | 江苏大学 | 一种生物素化Curli蛋白的活细胞标记方法及其应用 |
| GB202216905D0 (en) * | 2022-11-11 | 2022-12-28 | Oxford Nanopore Tech Plc | Novel pore monomers and pores |
| KR102855274B1 (ko) * | 2022-12-06 | 2025-09-08 | 충남대학교산학협력단 | strep-tag 결합물질에 대한 결합능을 가지는 융합단백질을 암호화하는 유전자 구조물 및 이를 함유하는 발현벡터, 재조합 균주 및 항암 조성물 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5762620A (en) | 1992-04-02 | 1998-06-09 | Ndm Acquisition Corp. | Wound dressing containing a partially dehydrated hydrogel |
| US6864365B1 (en) * | 1999-04-05 | 2005-03-08 | Innovation And Development Corporation, University Of Victoria | Bacterial fimbrial system for presentation of heterologous peptide sequences |
| DE60229867D1 (de) * | 2001-07-02 | 2008-12-24 | Merrion Res Iii Ltd | Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen |
| AU2003217415B2 (en) | 2002-02-14 | 2009-01-08 | William J Rutter | Chimeric molecules for cleavage in a treated host |
| PL1626799T3 (pl) | 2003-04-30 | 2010-09-30 | Univ Drexel | Mieszaniny polimerów żelujące w podwyższonej temperaturze, do stosowania w materiałach biokompatybilnych |
| EP1858546A4 (en) | 2005-03-04 | 2009-03-04 | Biorexis Pharmaceutical Corp | MODIFIED TRANSFERRINFUSION PROTEINS |
| EP3124614B1 (en) | 2007-01-12 | 2022-06-08 | Intrexon Actobiotics NV | Lactococcus promoters and uses thereof |
| JP2009073766A (ja) * | 2007-09-21 | 2009-04-09 | Otsuka Pharmaceut Co Ltd | 医薬 |
| WO2010111516A2 (en) | 2009-03-25 | 2010-09-30 | Whitehead Institute For Biomedical Research | Compositions and methods for inhibiting biofilms |
| US20110033389A1 (en) | 2009-04-29 | 2011-02-10 | Zhifeng Chen | Modified antibodies for passive immunotherapy |
| US20110108199A1 (en) | 2009-11-10 | 2011-05-12 | Tyco Healthcare Group Lp | Hemostatic Tapes and Dispensers Therefor |
| EP2536754A1 (en) * | 2010-02-16 | 2012-12-26 | Novo Nordisk A/S | Factor viii fusion protein |
| CA2830052C (en) | 2010-03-31 | 2018-10-09 | Wayne State University | Injectable dendrimer hydrogel nanoparticles |
| KR20110111594A (ko) | 2010-04-05 | 2011-10-12 | 서울대학교산학협력단 | 알파-시뉴클레인 유래 곱슬 아밀로이드 섬유의 제조방법, 이를 이용한 하이드로젤의 제조 방법 및 그 이용 방법 |
| US8741417B2 (en) | 2010-04-16 | 2014-06-03 | Korea University Research And Business Foundation | Films having switchable reflectivity |
| EP2624874A4 (en) | 2010-10-08 | 2014-04-02 | Univ Texas | Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications |
| BR112013008957A2 (pt) * | 2010-10-15 | 2019-09-24 | Univ Cornell | composições e métodos para tratamento de doenças endócrinas, gastrointestinais ou autoimunes |
| KR20120060442A (ko) | 2010-12-02 | 2012-06-12 | 가톨릭대학교 산학협력단 | 위암 진단용 마커로서 tff2의 용도 |
| US9140698B2 (en) * | 2011-04-06 | 2015-09-22 | The Board Of Regents Of The University Of Texas System | Modulating bacterial MAM polypeptides in pathogenic disease |
| US9580480B2 (en) * | 2011-05-31 | 2017-02-28 | Massachusetts Institute Of Technology | Cell-directed synthesis of multifunctional nanopatterns and nanomaterials |
| CN104271588B (zh) | 2011-07-08 | 2017-10-10 | 安米林药品有限责任公司 | 具有增强的作用持续时间和降低的免疫原性的工程改造的多肽 |
| EP2739312B1 (en) | 2011-08-03 | 2017-10-04 | Children's Medical Center Corporation | A broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza hemagglutinin |
| WO2013188529A1 (en) | 2012-06-15 | 2013-12-19 | Temple University Of The Commonwealth System Of Higher Education | Use of isolated bacterial amyloids for treatment of inflammatory disorders or diseases of the epithelium |
| AU2013293092A1 (en) * | 2012-07-23 | 2015-02-26 | Zymeworks Inc. | Immunoglobulin constructs comprising selective pairing of the light and heavy chains |
| WO2014078489A1 (en) | 2012-11-16 | 2014-05-22 | President And Fellows Of Harvard College | Methods and compositions relating to amyloidogenic polypeptides |
| HRP20191865T1 (hr) * | 2013-01-14 | 2020-01-10 | Xencor, Inc. | Novi heterodimerni proteini |
| JP2014156428A (ja) * | 2013-02-15 | 2014-08-28 | Univ Of Tokyo | 抗体結合タンパク質 |
| WO2014139468A1 (en) * | 2013-03-15 | 2014-09-18 | Admark Healthcare, Llc | Fusion protein molecules and method of use |
| US9815871B2 (en) | 2013-04-23 | 2017-11-14 | President And Fellows Of Harvard College | Genetic reprogramming of bacterial biofilms |
| WO2015080671A1 (en) | 2013-11-30 | 2015-06-04 | Agency For Science, Technology And Research | Self-assembling peptides, peptidomimetics and peptidic conjugates as building blocks for biofabrication and printing |
| WO2015097289A1 (en) | 2013-12-24 | 2015-07-02 | Vib Vzw | Secretion and functional display of chimeric polypeptides |
| US20150342893A1 (en) | 2014-05-29 | 2015-12-03 | Sigmoid Pharma Limited | Celecoxib formulations useful for treating colorectal cancer |
| JP6916524B2 (ja) | 2015-04-06 | 2021-08-11 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 機能的タンパク質配列をディスプレイする生合成アミロイドに基づく材料 |
| US11098133B2 (en) | 2016-05-19 | 2021-08-24 | President And Fellows Of Harvard College | Methods of making gels and films using curli nanofibers |
-
2016
- 2016-04-06 JP JP2017552146A patent/JP6916524B2/ja active Active
- 2016-04-06 WO PCT/US2016/026161 patent/WO2016164422A2/en not_active Ceased
- 2016-04-06 EP EP16777174.0A patent/EP3280397A4/en active Pending
- 2016-04-06 US US15/564,619 patent/US20180258435A1/en not_active Abandoned
-
2020
- 2020-02-10 US US16/785,874 patent/US11286491B2/en active Active
-
2021
- 2021-02-26 JP JP2021030187A patent/JP7156726B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20180258435A1 (en) | 2018-09-13 |
| US20200248190A1 (en) | 2020-08-06 |
| EP3280397A2 (en) | 2018-02-14 |
| WO2016164422A2 (en) | 2016-10-13 |
| EP3280397A4 (en) | 2018-08-22 |
| US11286491B2 (en) | 2022-03-29 |
| JP2021097687A (ja) | 2021-07-01 |
| WO2016164422A3 (en) | 2017-02-09 |
| JP2018517398A (ja) | 2018-07-05 |
| JP7156726B2 (ja) | 2022-10-19 |
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