JP6898240B2 - T細胞前駆細胞を生成するための方法 - Google Patents
T細胞前駆細胞を生成するための方法 Download PDFInfo
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- JP6898240B2 JP6898240B2 JP2017537016A JP2017537016A JP6898240B2 JP 6898240 B2 JP6898240 B2 JP 6898240B2 JP 2017537016 A JP2017537016 A JP 2017537016A JP 2017537016 A JP2017537016 A JP 2017537016A JP 6898240 B2 JP6898240 B2 JP 6898240B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/42—Notch; Delta; Jagged; Serrate
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1114—T cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1459539A FR3026744B1 (fr) | 2014-10-06 | 2014-10-06 | Methode de generation de progeniteurs de cellules t |
| FR1459539 | 2014-10-06 | ||
| PCT/EP2015/072889 WO2016055396A1 (fr) | 2014-10-06 | 2015-10-05 | Méthode de génération de progéniteurs de cellules t |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020209370A Division JP2021072779A (ja) | 2014-10-06 | 2020-12-17 | T細胞前駆細胞を生成するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017531448A JP2017531448A (ja) | 2017-10-26 |
| JP2017531448A5 JP2017531448A5 (enExample) | 2018-11-15 |
| JP6898240B2 true JP6898240B2 (ja) | 2021-07-07 |
Family
ID=52102849
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017537016A Active JP6898240B2 (ja) | 2014-10-06 | 2015-10-05 | T細胞前駆細胞を生成するための方法 |
| JP2020209370A Pending JP2021072779A (ja) | 2014-10-06 | 2020-12-17 | T細胞前駆細胞を生成するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020209370A Pending JP2021072779A (ja) | 2014-10-06 | 2020-12-17 | T細胞前駆細胞を生成するための方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12071635B2 (enExample) |
| EP (2) | EP3204492B1 (enExample) |
| JP (2) | JP6898240B2 (enExample) |
| CA (1) | CA2963756C (enExample) |
| DK (1) | DK3204492T3 (enExample) |
| ES (1) | ES2914082T3 (enExample) |
| FR (1) | FR3026744B1 (enExample) |
| HU (1) | HUE059468T2 (enExample) |
| PL (1) | PL3204492T3 (enExample) |
| PT (1) | PT3204492T (enExample) |
| WO (1) | WO2016055396A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3440198A4 (en) | 2016-04-08 | 2019-11-06 | The Governing Council of the Universtiy of Toronto | PROCESS FOR THE PRODUCTION OF PRE-TREATMENT T CELLS FROM TRUNK AND / OR PRECURSOR CELLS AND USE THEREOF |
| IL268641B2 (en) * | 2017-02-13 | 2024-10-01 | Assist Publique Hopitaux Paris Aphp | Method for generating t cells progenitors |
| CN112041431A (zh) * | 2018-02-14 | 2020-12-04 | 桑尼布鲁克研究所 | 产生t细胞谱系细胞的方法 |
| FR3079239A1 (fr) * | 2018-03-23 | 2019-09-27 | Centre National De La Recherche Scientifique | Nouvelle methode d’obtention de cellules t a partir de cellules souches pluripotentes, et leurs utilisations |
| EP3774867A1 (en) * | 2018-04-10 | 2021-02-17 | Stichting Sanquin Bloedvoorziening | Chimeric notch receptors |
| JP2023553313A (ja) | 2020-11-30 | 2023-12-21 | チョ ファーマ インコーポレイテッド | 細胞を富化するための抗体 |
| EP4426319A1 (en) | 2021-11-04 | 2024-09-11 | APHP (Assistance Publique - Hôpitaux de Paris) | Method for generating nk cells |
| WO2024175738A1 (en) | 2023-02-22 | 2024-08-29 | Smart Immune | Method for thymus regeneration |
| WO2025012449A1 (en) | 2023-07-12 | 2025-01-16 | Smart Immune | Biobank of cellular banks having specific homozygous hla haplotypes and uses thereof for treating patients |
| WO2025219552A1 (en) | 2024-04-17 | 2025-10-23 | Assitance Publique Hopitaux De Paris | Method for producing t cell progenitors from human pluripotent stem cells |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6093531A (en) | 1997-09-29 | 2000-07-25 | Neurospheres Holdings Ltd. | Generation of hematopoietic cells from multipotent neural stem cells |
| JP2001525176A (ja) | 1997-12-04 | 2001-12-11 | デューク・ユニバーシティー | Cd7+cd34−lin−造血細胞を単離し、使用する方法 |
| EA012520B1 (ru) * | 2003-08-22 | 2009-10-30 | Такара Био Инк. | Способ получения цитотоксических лимфоцитов |
| US10059923B2 (en) | 2008-01-30 | 2018-08-28 | Memorial Sloan Kettering Cancer Center | Methods for off-the-shelf tumor immunotherapy using allogeneic T-cell precursors |
| RU2535966C2 (ru) | 2008-09-12 | 2014-12-20 | Криопрашис Криобиоложия Лтда. | Клеточная терапия ишемической ткани |
| US8772028B2 (en) | 2008-11-07 | 2014-07-08 | Sunnybrook Health Sciences Centre | CD34+CD7+CD5+CD1a-human progenitor T-cells produced in vitro and methods of using |
| WO2011068962A1 (en) * | 2009-12-03 | 2011-06-09 | The University Of Utah Research Foundation | Methods for generating t lymphocytes from hematopoietic stem cells |
| US20130095079A1 (en) | 2010-04-09 | 2013-04-18 | Fred Hutchinson Cancer Research Center | Compositions and methods for providing hematopoietic function without hla matching |
| WO2013074916A1 (en) | 2011-11-18 | 2013-05-23 | Board Of Regents, The University Of Texas System | Car+ t cells genetically modified to eliminate expression of t- cell receptor and/or hla |
| US9834755B2 (en) | 2011-12-08 | 2017-12-05 | Fred Hutchinson Cancer Research Center | Compositions and methods for enhanced generation of hematopoietic stem/progenitor cells |
| WO2014110353A1 (en) * | 2013-01-11 | 2014-07-17 | The Trustees Of The University Of Pennsylvania | Notch ligand bound bicompatible substrates and their use in bone formation |
| EP3027755B1 (en) | 2013-08-02 | 2019-10-09 | The Regents of The University of California | Engineering antiviral t cell immunity through stem cells and chimeric antigen receptors |
| US20170128556A1 (en) | 2013-12-26 | 2017-05-11 | Thyas Co. Ltd. | Immunotherapy using t precursor cells derived from pluripotent stem cells having rearranged t cell receptor genes |
| KR20160145802A (ko) | 2014-04-23 | 2016-12-20 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 요법에 사용하기 위한 키메라 항원 수용체 (car) 및 이의 제조 방법 |
| US10131876B2 (en) | 2014-04-24 | 2018-11-20 | Miltenyi Biotec Gmbh | Method for automated generation of genetically modified T cells |
| WO2016039933A1 (en) * | 2014-09-11 | 2016-03-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Lentiviral vector for treating hemoglobin disorders |
-
2014
- 2014-10-06 FR FR1459539A patent/FR3026744B1/fr active Active
-
2015
- 2015-10-05 ES ES15771979T patent/ES2914082T3/es active Active
- 2015-10-05 EP EP15771979.0A patent/EP3204492B1/fr active Active
- 2015-10-05 WO PCT/EP2015/072889 patent/WO2016055396A1/fr not_active Ceased
- 2015-10-05 US US15/516,731 patent/US12071635B2/en active Active
- 2015-10-05 JP JP2017537016A patent/JP6898240B2/ja active Active
- 2015-10-05 PL PL15771979.0T patent/PL3204492T3/pl unknown
- 2015-10-05 PT PT157719790T patent/PT3204492T/pt unknown
- 2015-10-05 EP EP22152734.4A patent/EP4036224A1/fr not_active Withdrawn
- 2015-10-05 DK DK15771979.0T patent/DK3204492T3/da active
- 2015-10-05 HU HUE15771979A patent/HUE059468T2/hu unknown
- 2015-10-05 CA CA2963756A patent/CA2963756C/fr active Active
-
2020
- 2020-12-17 JP JP2020209370A patent/JP2021072779A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3204492A1 (fr) | 2017-08-16 |
| WO2016055396A1 (fr) | 2016-04-14 |
| ES2914082T8 (es) | 2022-06-16 |
| US20180208895A1 (en) | 2018-07-26 |
| PL3204492T3 (pl) | 2022-07-25 |
| EP4036224A1 (fr) | 2022-08-03 |
| HUE059468T2 (hu) | 2022-12-28 |
| FR3026744A1 (fr) | 2016-04-08 |
| EP3204492B1 (fr) | 2022-03-09 |
| CA2963756C (fr) | 2024-01-02 |
| JP2021072779A (ja) | 2021-05-13 |
| US12071635B2 (en) | 2024-08-27 |
| DK3204492T3 (da) | 2022-06-07 |
| PT3204492T (pt) | 2022-05-30 |
| ES2914082T3 (es) | 2022-06-07 |
| CA2963756A1 (fr) | 2016-04-14 |
| JP2017531448A (ja) | 2017-10-26 |
| FR3026744B1 (fr) | 2024-04-19 |
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