JP6871168B2 - 方法 - Google Patents

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Publication number
JP6871168B2
JP6871168B2 JP2017546051A JP2017546051A JP6871168B2 JP 6871168 B2 JP6871168 B2 JP 6871168B2 JP 2017546051 A JP2017546051 A JP 2017546051A JP 2017546051 A JP2017546051 A JP 2017546051A JP 6871168 B2 JP6871168 B2 JP 6871168B2
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Japan
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protein
binder
library
binding
target
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JP2017546051A
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Japanese (ja)
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JP2017536846A (ja
JP2017536846A5 (OSRAM
Inventor
ジェニー,チャバ
Original Assignee
ジーンビレッジ コルラートルト フェレレーシェシェーギュー タールシャシャーグ
ジーンビレッジ コルラートルト フェレレーシェシェーギュー タールシャシャーグ
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/10Oligonucleotides as tagging agents for labelling antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2017546051A 2014-11-24 2015-11-24 方法 Active JP6871168B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1420852.4 2014-11-24
GBGB1420852.4A GB201420852D0 (en) 2014-11-24 2014-11-24 Method
PCT/GB2015/053573 WO2016083793A1 (en) 2014-11-24 2015-11-24 Method

Publications (3)

Publication Number Publication Date
JP2017536846A JP2017536846A (ja) 2017-12-14
JP2017536846A5 JP2017536846A5 (OSRAM) 2018-12-27
JP6871168B2 true JP6871168B2 (ja) 2021-05-12

Family

ID=52292436

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017546051A Active JP6871168B2 (ja) 2014-11-24 2015-11-24 方法

Country Status (10)

Country Link
US (3) US10605814B2 (OSRAM)
EP (1) EP3224360B1 (OSRAM)
JP (1) JP6871168B2 (OSRAM)
KR (1) KR102422494B1 (OSRAM)
CN (1) CN107430130B (OSRAM)
CA (1) CA2968488C (OSRAM)
ES (1) ES2763563T3 (OSRAM)
GB (1) GB201420852D0 (OSRAM)
SG (2) SG10202008300RA (OSRAM)
WO (1) WO2016083793A1 (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017214211A1 (en) * 2016-06-09 2017-12-14 Igc Bio, Inc. Methods for identifying a high affinity antibody
JP7714325B2 (ja) * 2017-01-31 2025-07-29 48アワー ディスカバリー インコーポレイテッド 相乗的分子相互作用を決定するための、サイレントに遺伝的にコード化されたナノスケールキャリア上の分子のディスプレイ
WO2019085958A1 (zh) * 2017-11-06 2019-05-09 清华大学 检测生物分子间相互作用及其调控因子的成套试剂与应用
JP7723599B2 (ja) 2018-07-23 2025-08-14 48アワー ディスカバリー インコーポレイテッド 遺伝的にコードされた二環式ペプチドライブラリー
CN114041055A (zh) 2019-06-25 2022-02-11 阿克托姆有限责任公司 用于以双组分体系测量分析物的方法和试剂盒及其用途
CN115066434A (zh) 2019-12-03 2022-09-16 阿拉玛生物科学公司 核酸连接的免疫-夹心测定(nulisa)
EP4330678A1 (en) * 2021-04-26 2024-03-06 Ecole Polytechnique Federale De Lausanne (Epfl) High complexity microcompartment-based interaction screening
EP4242656A1 (en) * 2022-03-10 2023-09-13 Actome GmbH Quantitative detection method and corresponding device
EP4547862A1 (en) 2022-06-29 2025-05-07 Actome GmbH Detection of biomolecules in single cells
GB202218453D0 (en) 2022-12-08 2023-01-25 Actome Gmbh Assay system

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
ES2156149T3 (es) 1992-12-04 2001-06-16 Medical Res Council Proteinas de union multivalente y multiespecificas, su fabricacion y su uso.
US7306904B2 (en) 2000-02-18 2007-12-11 Olink Ab Methods and kits for proximity probing
GB0422431D0 (en) * 2004-10-08 2004-11-10 Affitech As Method
EP2209893B1 (en) * 2007-10-12 2013-11-20 Pronota NV Use of aptamers in proteomics
GB0903316D0 (en) * 2009-02-26 2009-04-08 Affitech As Method
RU2562163C2 (ru) * 2009-05-20 2015-09-10 Новиммун С.А. Библиотеки синтетических полипептидов и способы получения вариантов полипептидов с естественным разнообразием
SG177395A1 (en) * 2009-07-07 2012-02-28 Agency Science Tech & Res Methods of identifying a pair of binding partners
CN103119165B (zh) * 2010-09-27 2017-04-12 威泊根私人有限公司 制备富集文库的方法
US9209965B2 (en) 2014-01-14 2015-12-08 Microsemi Semiconductor Ulc Network interface with clock recovery module on line card

Also Published As

Publication number Publication date
US11421347B2 (en) 2022-08-23
GB201420852D0 (en) 2015-01-07
US20230175171A1 (en) 2023-06-08
ES2763563T3 (es) 2020-05-29
JP2017536846A (ja) 2017-12-14
US20210003585A1 (en) 2021-01-07
EP3224360A1 (en) 2017-10-04
WO2016083793A1 (en) 2016-06-02
US10605814B2 (en) 2020-03-31
SG11201703689SA (en) 2017-06-29
KR102422494B1 (ko) 2022-07-19
CN107430130A (zh) 2017-12-01
CA2968488C (en) 2024-09-10
SG10202008300RA (en) 2020-10-29
CA2968488A1 (en) 2016-06-02
US20170269098A1 (en) 2017-09-21
CN107430130B (zh) 2020-07-24
EP3224360B1 (en) 2019-10-09
KR20170086627A (ko) 2017-07-26

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