JP6866988B2 - 誘導された樹状細胞およびその使用 - Google Patents

誘導された樹状細胞およびその使用 Download PDF

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JP6866988B2
JP6866988B2 JP2015556448A JP2015556448A JP6866988B2 JP 6866988 B2 JP6866988 B2 JP 6866988B2 JP 2015556448 A JP2015556448 A JP 2015556448A JP 2015556448 A JP2015556448 A JP 2015556448A JP 6866988 B2 JP6866988 B2 JP 6866988B2
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レナータ・シュトリペケ
グスタボ・サルゲロ−ロペス
アヌサラ・ダエンタナサンマク
アーノルト・ガンザー
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Medizinische Hochschule Hannover
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/19—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
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    • A61K40/24—Antigen-presenting cells [APC]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/418—Antigens related to induction of tolerance to non-self
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0337—Animal models for infectious diseases
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  • Urology & Nephrology (AREA)
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JP2015556448A 2013-02-07 2014-01-24 誘導された樹状細胞およびその使用 Expired - Fee Related JP6866988B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EPPCT/EP2013/052485 2013-02-07
PCT/EP2013/052485 WO2014121840A1 (en) 2013-02-07 2013-02-07 Induced dendritic cells and uses thereof
PCT/EP2014/051422 WO2014122035A2 (en) 2013-02-07 2014-01-24 Induced dendritic cells and uses thereof

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JP2016513953A JP2016513953A (ja) 2016-05-19
JP2016513953A5 JP2016513953A5 (enExample) 2017-03-02
JP6866988B2 true JP6866988B2 (ja) 2021-04-28

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JP2015556448A Expired - Fee Related JP6866988B2 (ja) 2013-02-07 2014-01-24 誘導された樹状細胞およびその使用

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US (2) US10272111B2 (enExample)
JP (1) JP6866988B2 (enExample)
CN (1) CN105025924A (enExample)
CA (1) CA2899786C (enExample)
WO (2) WO2014121840A1 (enExample)

Families Citing this family (15)

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Publication number Priority date Publication date Assignee Title
CN105039256A (zh) * 2015-07-13 2015-11-11 中政道和（北京）生物科技有限公司 一种支气管镜下获取肿瘤组织进行树突细胞培养扩增方法
US11834675B2 (en) 2015-12-30 2023-12-05 Celgene Corporation T lymphocyte production methods and t lymphocytes produced thereby
KR102646596B1 (ko) * 2016-12-21 2024-03-13 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 입양 세포 요법에서 t 세포 활성화를 매개하는 ccr2+ 조혈 줄기 세포
US20200208108A1 (en) * 2017-05-10 2020-07-02 Aarhus Universitet Interferon primed plasmacytoid dendritic cells
EP3672617A4 (en) * 2017-08-22 2021-06-23 The Regents of the University of California LENTIVIRAL VECTORS EXPRESSING FOXP3 IN HEMATOPOIETIC STEM CELLS TO TREAT IMMUNITY DEFICIENCIES AND AUTOIMMUNE DISEASES
BR112021000620A2 (pt) 2018-07-15 2021-04-20 Enochian BioPharma, Inc. métodos e composições com uso de células dendríticas recombinantes para terapia contra câncer
CA3161488A1 (en) * 2019-12-11 2021-06-17 Daniel Getts Therapeutic cell compositions and methods for manufacture and uses thereof
US10980836B1 (en) * 2019-12-11 2021-04-20 Myeloid Therapeutics, Inc. Therapeutic cell compositions and methods of manufacturing and use thereof
CN116194221A (zh) * 2020-05-28 2023-05-30 生物磁学解决方案有限责任公司 用单一抗体阴性选择幼稚t细胞和b细胞的组合物和方法
CN111647563A (zh) * 2020-08-06 2020-09-11 北京翊博普惠生物科技发展有限公司 靶向Survivin全抗原的DC细胞、CTL细胞及其制备方法和应用
US20240002798A1 (en) * 2020-11-17 2024-01-04 Research & Business Foundation Sungkyunkwan University Method for preparing immunogenicity-enhanced cd103+ fcgr3+ dendritic cell by treatment with interleukin-33 and pharmaceutical composition comprising same dendritic cell for cancer immunotherapy
BR112023018832A2 (pt) 2021-03-17 2023-12-26 Myeloid Therapeutics Inc Composições de proteínas de fusão quiméricas modificadas e métodos de uso das mesmas
EP4337268A4 (en) 2021-05-11 2025-06-04 Myeloid Therapeutics, Inc. Methods and compositions for genomic integration
CN113881631B (zh) * 2021-10-11 2022-08-02 北京翊博普惠生物科技发展有限公司 一种扁桃体来源的Tγδ细胞及其制备方法和应用
CN117625531A (zh) * 2022-08-30 2024-03-01 浙江吉量科技有限公司 树突细胞祖细胞的制备方法及其培养基

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102725400A (zh) * 2009-06-29 2012-10-10 麻省理工学院 制造人源化的非人类哺乳动物的方法
DE102012207453B4 (de) 2012-05-04 2017-10-19 Technische Universität Dresden Humanisierte Mäuse ohne Konditionierung

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WO2014122035A2 (en) 2014-08-14
WO2014122035A3 (en) 2014-10-23
CA2899786C (en) 2023-03-07
CA2899786A1 (en) 2014-08-14
US10272111B2 (en) 2019-04-30
US20160038541A1 (en) 2016-02-11
WO2014122035A9 (en) 2014-12-11
CN105025924A (zh) 2015-11-04
JP2016513953A (ja) 2016-05-19
US20190247430A1 (en) 2019-08-15
US11413307B2 (en) 2022-08-16
WO2014121840A1 (en) 2014-08-14

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