JP6859275B2 - 膀胱がんの治療方法 - Google Patents

膀胱がんの治療方法 Download PDF

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Publication number
JP6859275B2
JP6859275B2 JP2017568016A JP2017568016A JP6859275B2 JP 6859275 B2 JP6859275 B2 JP 6859275B2 JP 2017568016 A JP2017568016 A JP 2017568016A JP 2017568016 A JP2017568016 A JP 2017568016A JP 6859275 B2 JP6859275 B2 JP 6859275B2
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JP
Japan
Prior art keywords
mitomycin
liposome
prodrug
bladder cancer
liposomes
Prior art date
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Active
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JP2017568016A
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English (en)
Japanese (ja)
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JP2018508589A5 (enExample
JP2018508589A (ja
Inventor
アルベルト・ガビゾン
パトリシア・オハナ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patricia Ohana
Lipomedix Pharmaceuticals Ltd
Original Assignee
Patricia Ohana
Lipomedix Pharmaceuticals Ltd
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Publication of JP2018508589A5 publication Critical patent/JP2018508589A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2017568016A 2015-03-17 2016-03-17 膀胱がんの治療方法 Active JP6859275B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562134328P 2015-03-17 2015-03-17
US62/134,328 2015-03-17
PCT/US2016/022909 WO2016149516A1 (en) 2015-03-17 2016-03-17 Methods for the treatment of bladder cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020188037A Division JP2021035973A (ja) 2015-03-17 2020-11-11 膀胱がんの治療方法

Publications (3)

Publication Number Publication Date
JP2018508589A JP2018508589A (ja) 2018-03-29
JP2018508589A5 JP2018508589A5 (enExample) 2019-04-25
JP6859275B2 true JP6859275B2 (ja) 2021-04-14

Family

ID=56919480

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017568016A Active JP6859275B2 (ja) 2015-03-17 2016-03-17 膀胱がんの治療方法
JP2020188037A Withdrawn JP2021035973A (ja) 2015-03-17 2020-11-11 膀胱がんの治療方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020188037A Withdrawn JP2021035973A (ja) 2015-03-17 2020-11-11 膀胱がんの治療方法

Country Status (6)

Country Link
US (1) US20180071253A1 (enExample)
EP (1) EP3270898B1 (enExample)
JP (2) JP6859275B2 (enExample)
AU (1) AU2016233143B2 (enExample)
CA (1) CA2985330A1 (enExample)
WO (1) WO2016149516A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3126211A1 (en) * 2019-01-11 2020-07-16 Lipomedix Pharmaceuticals Ltd. Liposome composition comprising liposomal prodrug of mitomycin c and method of manufacture

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5395619A (en) 1993-03-03 1995-03-07 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes
US5817856A (en) 1995-12-11 1998-10-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Radiation-protective phospholipid and method
WO1998007409A1 (en) 1996-08-23 1998-02-26 Sequus Pharmaceuticals, Inc. Liposomes containing a cisplatin compound
EP0932390A1 (en) 1996-10-11 1999-08-04 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method
EP1880736A1 (en) 1999-04-23 2008-01-23 Alza Corporation Releasable linkage and composition containing same
US7303760B2 (en) * 1999-04-23 2007-12-04 Alza Corporation Method for treating multi-drug resistant tumors
EP1504010B1 (en) * 2002-05-15 2009-03-25 Endocyte, Inc. Vitamin-mitomycin conjugates
WO2015191576A1 (en) * 2014-06-09 2015-12-17 Lipomedix Pharmaceuticals Ltd. Combination therapy comprising a liposomal prodrug of mitomycin c and radiotherapy

Also Published As

Publication number Publication date
AU2016233143A1 (en) 2017-10-19
EP3270898A4 (en) 2018-10-31
JP2021035973A (ja) 2021-03-04
AU2016233143B2 (en) 2021-03-25
WO2016149516A1 (en) 2016-09-22
US20180071253A1 (en) 2018-03-15
JP2018508589A (ja) 2018-03-29
CA2985330A1 (en) 2016-09-22
EP3270898A1 (en) 2018-01-24
EP3270898B1 (en) 2021-05-05

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