JP6859275B2 - 膀胱がんの治療方法 - Google Patents

膀胱がんの治療方法 Download PDF

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Publication number
JP6859275B2
JP6859275B2 JP2017568016A JP2017568016A JP6859275B2 JP 6859275 B2 JP6859275 B2 JP 6859275B2 JP 2017568016 A JP2017568016 A JP 2017568016A JP 2017568016 A JP2017568016 A JP 2017568016A JP 6859275 B2 JP6859275 B2 JP 6859275B2
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JP
Japan
Prior art keywords
mitomycin
liposome
prodrug
bladder cancer
liposomes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2017568016A
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English (en)
Japanese (ja)
Other versions
JP2018508589A (ja
JP2018508589A5 (enExample
Inventor
アルベルト・ガビゾン
パトリシア・オハナ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Patricia Ohana
Lipomedix Pharmaceuticals Ltd
Original Assignee
Patricia Ohana
Lipomedix Pharmaceuticals Ltd
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Publication date
Application filed by Patricia Ohana, Lipomedix Pharmaceuticals Ltd filed Critical Patricia Ohana
Publication of JP2018508589A publication Critical patent/JP2018508589A/ja
Publication of JP2018508589A5 publication Critical patent/JP2018508589A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2017568016A 2015-03-17 2016-03-17 膀胱がんの治療方法 Expired - Fee Related JP6859275B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562134328P 2015-03-17 2015-03-17
US62/134,328 2015-03-17
PCT/US2016/022909 WO2016149516A1 (en) 2015-03-17 2016-03-17 Methods for the treatment of bladder cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020188037A Division JP2021035973A (ja) 2015-03-17 2020-11-11 膀胱がんの治療方法

Publications (3)

Publication Number Publication Date
JP2018508589A JP2018508589A (ja) 2018-03-29
JP2018508589A5 JP2018508589A5 (enExample) 2019-04-25
JP6859275B2 true JP6859275B2 (ja) 2021-04-14

Family

ID=56919480

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017568016A Expired - Fee Related JP6859275B2 (ja) 2015-03-17 2016-03-17 膀胱がんの治療方法
JP2020188037A Withdrawn JP2021035973A (ja) 2015-03-17 2020-11-11 膀胱がんの治療方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020188037A Withdrawn JP2021035973A (ja) 2015-03-17 2020-11-11 膀胱がんの治療方法

Country Status (5)

Country Link
US (1) US20180071253A1 (enExample)
EP (1) EP3270898B1 (enExample)
JP (2) JP6859275B2 (enExample)
AU (1) AU2016233143B2 (enExample)
WO (1) WO2016149516A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12171746B2 (en) 2019-01-11 2024-12-24 Lipomedix Pharmaceuticals Ltd. Liposome composition comprising liposomal prodrug of mitomycin c and method of manufacture

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5395619A (en) 1993-03-03 1995-03-07 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes
US5817856A (en) 1995-12-11 1998-10-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Radiation-protective phospholipid and method
DE69725747T2 (de) 1996-08-23 2004-07-29 Sequus Pharmaceuticals, Inc., Menlo Park Liposome enthaltend cisplatin
AU4907897A (en) 1996-10-11 1998-05-11 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method
US7303760B2 (en) * 1999-04-23 2007-12-04 Alza Corporation Method for treating multi-drug resistant tumors
KR100642955B1 (ko) 1999-04-23 2006-11-10 알자 코포레이션 방출성 결합 및 그를 함유하는 조성물
CA2484640C (en) * 2002-05-15 2012-01-17 Endocyte, Inc. Vitamin-mitomycin conjugates
WO2015191576A1 (en) * 2014-06-09 2015-12-17 Lipomedix Pharmaceuticals Ltd. Combination therapy comprising a liposomal prodrug of mitomycin c and radiotherapy

Also Published As

Publication number Publication date
AU2016233143A1 (en) 2017-10-19
JP2021035973A (ja) 2021-03-04
AU2016233143B2 (en) 2021-03-25
EP3270898A4 (en) 2018-10-31
EP3270898B1 (en) 2021-05-05
JP2018508589A (ja) 2018-03-29
WO2016149516A1 (en) 2016-09-22
CA2985330A1 (en) 2016-09-22
EP3270898A1 (en) 2018-01-24
US20180071253A1 (en) 2018-03-15

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