JP2018508589A5 - - Google Patents
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- Publication number
- JP2018508589A5 JP2018508589A5 JP2017568016A JP2017568016A JP2018508589A5 JP 2018508589 A5 JP2018508589 A5 JP 2018508589A5 JP 2017568016 A JP2017568016 A JP 2017568016A JP 2017568016 A JP2017568016 A JP 2017568016A JP 2018508589 A5 JP2018508589 A5 JP 2018508589A5
- Authority
- JP
- Japan
- Prior art keywords
- bladder cancer
- individual
- composition according
- liposome composition
- mitomycin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical compound C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 8
- 206010005003 Bladder cancer Diseases 0.000 claims 7
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 7
- 239000002502 liposome Substances 0.000 claims 7
- 201000005112 urinary bladder cancer Diseases 0.000 claims 7
- 229960004857 mitomycin Drugs 0.000 claims 4
- 229940002612 prodrug Drugs 0.000 claims 3
- 239000000651 prodrug Substances 0.000 claims 3
- 239000003638 chemical reducing agent Substances 0.000 claims 1
- 229940014144 folate Drugs 0.000 claims 1
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims 1
- 235000019152 folic acid Nutrition 0.000 claims 1
- 239000011724 folic acid Substances 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 230000000717 retained effect Effects 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562134328P | 2015-03-17 | 2015-03-17 | |
| US62/134,328 | 2015-03-17 | ||
| PCT/US2016/022909 WO2016149516A1 (en) | 2015-03-17 | 2016-03-17 | Methods for the treatment of bladder cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020188037A Division JP2021035973A (ja) | 2015-03-17 | 2020-11-11 | 膀胱がんの治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018508589A JP2018508589A (ja) | 2018-03-29 |
| JP2018508589A5 true JP2018508589A5 (enExample) | 2019-04-25 |
| JP6859275B2 JP6859275B2 (ja) | 2021-04-14 |
Family
ID=56919480
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017568016A Active JP6859275B2 (ja) | 2015-03-17 | 2016-03-17 | 膀胱がんの治療方法 |
| JP2020188037A Withdrawn JP2021035973A (ja) | 2015-03-17 | 2020-11-11 | 膀胱がんの治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020188037A Withdrawn JP2021035973A (ja) | 2015-03-17 | 2020-11-11 | 膀胱がんの治療方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20180071253A1 (enExample) |
| EP (1) | EP3270898B1 (enExample) |
| JP (2) | JP6859275B2 (enExample) |
| AU (1) | AU2016233143B2 (enExample) |
| CA (1) | CA2985330A1 (enExample) |
| WO (1) | WO2016149516A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3126211A1 (en) * | 2019-01-11 | 2020-07-16 | Lipomedix Pharmaceuticals Ltd. | Liposome composition comprising liposomal prodrug of mitomycin c and method of manufacture |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5395619A (en) | 1993-03-03 | 1995-03-07 | Liposome Technology, Inc. | Lipid-polymer conjugates and liposomes |
| US5817856A (en) | 1995-12-11 | 1998-10-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Radiation-protective phospholipid and method |
| WO1998007409A1 (en) | 1996-08-23 | 1998-02-26 | Sequus Pharmaceuticals, Inc. | Liposomes containing a cisplatin compound |
| EP0932390A1 (en) | 1996-10-11 | 1999-08-04 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method |
| EP1880736A1 (en) | 1999-04-23 | 2008-01-23 | Alza Corporation | Releasable linkage and composition containing same |
| US7303760B2 (en) * | 1999-04-23 | 2007-12-04 | Alza Corporation | Method for treating multi-drug resistant tumors |
| EP1504010B1 (en) * | 2002-05-15 | 2009-03-25 | Endocyte, Inc. | Vitamin-mitomycin conjugates |
| WO2015191576A1 (en) * | 2014-06-09 | 2015-12-17 | Lipomedix Pharmaceuticals Ltd. | Combination therapy comprising a liposomal prodrug of mitomycin c and radiotherapy |
-
2016
- 2016-03-17 JP JP2017568016A patent/JP6859275B2/ja active Active
- 2016-03-17 CA CA2985330A patent/CA2985330A1/en active Pending
- 2016-03-17 AU AU2016233143A patent/AU2016233143B2/en not_active Ceased
- 2016-03-17 WO PCT/US2016/022909 patent/WO2016149516A1/en not_active Ceased
- 2016-03-17 US US15/559,395 patent/US20180071253A1/en not_active Abandoned
- 2016-03-17 EP EP16765759.2A patent/EP3270898B1/en active Active
-
2020
- 2020-11-11 JP JP2020188037A patent/JP2021035973A/ja not_active Withdrawn
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