JP6858713B2 - 細胞をマイクロキャリアから分離するための方法及び装置 - Google Patents

細胞をマイクロキャリアから分離するための方法及び装置 Download PDF

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Publication number
JP6858713B2
JP6858713B2 JP2017561851A JP2017561851A JP6858713B2 JP 6858713 B2 JP6858713 B2 JP 6858713B2 JP 2017561851 A JP2017561851 A JP 2017561851A JP 2017561851 A JP2017561851 A JP 2017561851A JP 6858713 B2 JP6858713 B2 JP 6858713B2
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chamber
microcarriers
cells
filtration element
drug
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Japanese (ja)
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JP2018519809A (ja
JP2018519809A5 (de
Inventor
ノーマンド・ダヴィドゾン
ポール・シモンズ
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メゾブラスト・インターナショナル・エスアーエールエル
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Priority claimed from AU2015901998A external-priority patent/AU2015901998A0/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D33/00—Filters with filtering elements which move during the filtering operation
    • B01D33/01—Filters with filtering elements which move during the filtering operation with translationally moving filtering elements, e.g. pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D33/00—Filters with filtering elements which move during the filtering operation
    • B01D33/01—Filters with filtering elements which move during the filtering operation with translationally moving filtering elements, e.g. pistons
    • B01D33/0108—Filters with filtering elements which move during the filtering operation with translationally moving filtering elements, e.g. pistons with bag, cage, hose, tube, sleeve or the like filtering elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
    • B01D35/02—Filters adapted for location in special places, e.g. pipe-lines, pumps, stop-cocks
    • B01D35/027—Filters adapted for location in special places, e.g. pipe-lines, pumps, stop-cocks rigidly mounted in or on tanks or reservoirs
    • B01D35/0276—Filtering elements with a vertical rotation or symmetry axis mounted on tanks or reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D39/00—Filtering material for liquid or gaseous fluids
    • B01D39/10—Filter screens essentially made of metal
    • B01D39/12—Filter screens essentially made of metal of wire gauze; of knitted wire; of expanded metal
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Textile Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2017561851A 2015-05-29 2016-05-27 細胞をマイクロキャリアから分離するための方法及び装置 Active JP6858713B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2015901998 2015-05-29
AU2015901998A AU2015901998A0 (en) 2015-05-29 Methods and apparatus for separating cells from microcarriers
PCT/EP2016/062016 WO2016193150A1 (en) 2015-05-29 2016-05-27 Methods and apparatus for separating cells from microcarriers

Publications (3)

Publication Number Publication Date
JP2018519809A JP2018519809A (ja) 2018-07-26
JP2018519809A5 JP2018519809A5 (de) 2019-06-27
JP6858713B2 true JP6858713B2 (ja) 2021-04-14

Family

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Application Number Title Priority Date Filing Date
JP2017561851A Active JP6858713B2 (ja) 2015-05-29 2016-05-27 細胞をマイクロキャリアから分離するための方法及び装置

Country Status (7)

Country Link
US (1) US11242506B2 (de)
EP (1) EP3303549B1 (de)
JP (1) JP6858713B2 (de)
CN (1) CN107849507B (de)
ES (1) ES2762977T3 (de)
HK (1) HK1249763A1 (de)
WO (1) WO2016193150A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102538795B1 (ko) * 2016-11-11 2023-05-31 오리바이오테크 엘티디 세포 배양 장치 시스템 및 그의 사용 방법
CN111433344B (zh) 2017-11-30 2024-04-26 康宁股份有限公司 无菌干燥转移的方法和装置
JP7384207B2 (ja) * 2019-09-09 2023-11-21 株式会社村田製作所 濃縮装置及び濃縮方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4062773A (en) * 1974-09-30 1977-12-13 Baxter Travenol Laboratories, Inc. High surface to volume structure and method of generating same
DE3739649A1 (de) 1987-11-23 1989-06-22 Immuno Ag Verfahren zum abloesen von zellkulturen von mikrotraegern
JP3289984B2 (ja) * 1993-03-19 2002-06-10 株式会社日立製作所 生体の細胞の培養装置及び培養方法
JPH06296274A (ja) 1993-04-09 1994-10-21 Matsushita Electric Ind Co Ltd 画像符号化装置
DE69835813T2 (de) 1997-01-31 2007-09-13 Schering Corp. Verfahren zur kultivierung von zellen und zur vermehrung von viren
US7033823B2 (en) 2002-01-31 2006-04-25 Cesco Bioengineering, Inc. Cell-cultivating device
CN1260343C (zh) * 2002-01-31 2006-06-21 赛宇细胞科技股份有限公司 细胞培养装置
CN1300297C (zh) 2002-09-20 2007-02-14 华东理工大学 一种用于动物细胞扩大接种的消化反应器
US20070224676A1 (en) * 2006-03-21 2007-09-27 Becton, Dickinson And Company Expandable culture roller bottle
US7807052B2 (en) * 2008-09-18 2010-10-05 Milne John D Apparatus for buoyancy driven filtration
JP2010252635A (ja) 2009-04-21 2010-11-11 Olympus Corp 細胞処理装置
CN101775364A (zh) 2010-03-05 2010-07-14 广州齐志生物工程设备有限公司 一种动物细胞的分离方法及分离装置
CN102337200A (zh) 2010-07-20 2012-02-01 北京心意圆成生物科技有限公司 一种高效微载体细胞-培养基分离装置
CN201933090U (zh) 2010-11-22 2011-08-17 朱学仁 细胞微载体灌注培养截留装置
US9376655B2 (en) 2011-09-29 2016-06-28 Life Technologies Corporation Filter systems for separating microcarriers from cell culture solutions
CN202415566U (zh) 2012-01-10 2012-09-05 王秋艳 微胶囊及微载体过滤装置
US9333447B2 (en) * 2012-10-19 2016-05-10 Warsaw Orthopedic, Inc. Filtration device
CN203947105U (zh) * 2014-06-20 2014-11-19 上海日泰医药设备工程有限公司 一种细胞消化设备

Also Published As

Publication number Publication date
ES2762977T3 (es) 2020-05-26
EP3303549B1 (de) 2019-10-02
EP3303549A1 (de) 2018-04-11
US20180142201A1 (en) 2018-05-24
US11242506B2 (en) 2022-02-08
CN107849507B (zh) 2022-06-28
CN107849507A (zh) 2018-03-27
JP2018519809A (ja) 2018-07-26
HK1249763A1 (zh) 2018-11-09
WO2016193150A1 (en) 2016-12-08

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